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European Technology Platform for Global Animal Health (ETPGAH)

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Title: European Technology Platform for Global Animal Health (ETPGAH)


1
European Technology Platform for Global Animal
Health (ETPGAH)
  • Danish Mirror Group
  • Ideas to be transformed into research projects
  • Copenhagen
  • 8 September 2009
  • Jim Scudamore

2
Ideas to be transformed into research projects
  • Outline of the Presentation.
  • Introduction
  • The Action Plan
  • Danish Proposals
  • Funding of Proposals
  • Conclusions

3
ETP Global Animal HealthThe Vision
  • To facilitate and accelerate the development and
    distribution of the most effective tools for
    controlling animal diseases of major importance
    to Europe and the rest of the world, thereby
    improving human and animal health, food safety
    and quality, animal welfare, and market access,
    contributing to achieving the Millennium
    Development Goals.

Published August 2005
4
ETP Global Animal HealthThe Strategic Research
Agenda
  • The SRA is the mechanism to deliver the vision.
  • SRA has 2 overarching objectives-
  • to deliver new and improved tools for the control
    of major diseases and
  • to deliver the 61 recommendations within the 6
    themes of the SRA which in turn will facilitate
    the development and delivery of new tools

Published May 2006
5
ETP Global Animal HealthAction plan
  • 61 Recommendations
  • Proposals concerning what needs to be done
  • Action Plan is much more specific
  • Designed to be converted into research or
    information gathering initiatives

Published July 2007
6
ETP Global Animal HealthAction plan
  • The Action Plan is intended to be a flexible
    working document, subject to regular review and
    up dating by the ETPGAH to ensure that the SRA is
    on target and that the recommendations are being
    delivered.

Published July 2007
7
ETP Global Animal HealthThe Process
DISCONTOOL 2008
Stakeholders, led by industry, come together
to agree on a common vision for the technology
Stakeholders, define a Strategic Research
Agenda setting the necessary mid- to longterm
objectives
Stakeholders, implement the Strategic
Research Agenda with the mobilisation of
significant human and financial resources
EMIDA 2008
ICONZ 2009
Vision paper EU TP Global Animal
Health Launch Dec 2004 Final version August
2005
Strategic Research Agenda Published May 2006
Action Plan Published July 2007
Examples from FP7
8
Ideas to be transformed into research projects
  • Outline of the Presentation.
  • Introduction
  • The ETPGAH Action Plan
  • Danish Proposals
  • Funding of Proposals
  • Conclusions

9
ETP Global Animal HealthAction plan
  • Chapter 2 details the actions to implement the
    61 recommendations of the SRA using a standard
    format for consistency

10
ETP Global Animal HealthAction plan
Contents of the plan Chapter 2 Themes
Recommendations within themes Detailed Proposals
4 Enabling factors 17
5 Regulatory Societal Issues 8
1 Prioritise animal diseases and infections 8
3 Fundamental Science 5
6 Global Perspective 5
2 Gap Analysis 8
Action plan
Finalised and submitted to the EU Commission in
July 2007
11
ETP Global Animal HealthAction plan
  • Chapter 3 Deals with the research requirements
    for the priority diseases specifically dealing
    with prioritisation and gap analysis

12
ETP Global Animal HealthAction plan
  • Annex 1 Tasks for the European Centre for
    Epidemiology and Infectious animal disease
  • Annex 2 Categories of Disease
  • Annex 3 Prioritisation Model
  • Annex 4 Bluetongue Disease Information
  • Annex 5 Bluetongue Gap Analysis

13
ETP Global Animal HealthAction Plan
  • How will the action plan be used.
  • Template
  • Guidance
  • Liaison
  • Lobbying
  • Funding

14
ETP Global Animal HealthAction Plan
  • The Action plan serves to provide an input for-
  •  
  • Future EC Framework Programmes which will involve
    close cooperation with EC, Member States and
    European Parliament representatives.
  • Future national research programmes where it will
    provide better opportunities to align and
    coordinate national programmes
  • Public/private research partnerships exploring
    ways to develop an integrated approach to
    developing new tools to control animal diseases.
  • Industry which has an important role working in
    partnership to develop new products, which can be
    delivered in the field.

15
Ideas to be transformed into research projects
  • Outline of the Presentation.
  • Introduction
  • The Action Plan
  • Danish Proposals
  • Funding of Proposals
  • Conclusions

16
ETP Global Animal HealthDanish Proposals and the
Action Plan
  • Proposals
  • A European Academic Network for Vaccine Research
  • Coordination of Veterinary Epidemiological
    Research on Infectious Diseases in Europe
  • Endemic diseases
  • Questions
  • What is new?
  • How do these proposals fit into the action plan?
  • What are the priority diseases?
  • What is an endemic disease?
  • What benefits would they bring?
  • What is the best way forward?

17
A European Academic Network for Vaccine Research.
  • Objectives
  • To promote the development of vaccines for
    endemic diseases including MUMS
  • Deliverables
  • To support all aspects of design, development and
    testing of vaccines and strengthen collaboration
    (AP3.1)
  • To train young researchers. (AP 4.5)
  • To advise and propose strategies for future
    research of more generic and fundamental nature
    in all aspects of vaccine development.(AP4.3)
  • To provide information, advice and decision
    support to European authorities.
  • To identify the main problems related to vaccine
    research from the perspective of all stakeholders
  • To identify global centres of excellence
  • To identify subjects and areas of importance in
    relation to innate immunity, T-cell immunity, DNA
    vaccines, Bio-informatics, antigen delivery
    systems.(AP3.3). Genomic and proteomic approach

18
Coordination of Veterinary Epidemiological
Research on Infectious Diseases in Europe (1)
  • Objectives
  • To ensure the coordination of research and
    education activities in the area of veterinary
    epidemiology of infectious diseases.
  • Deliverables
  • To create a cost effective body to coordinate
    animal health research at a European level.
  • To act as a coordination body for epidemiology in
    the EU
  • To train young researchers. (AP 4.5)
  • To initiate timely projects related to veterinary
    epidemiological research into infectious
    diseases.
  • To provide objective, transparent, and
    comparable information concerning the occurrence,
    dissemination and control of animal diseases.
  • To provide easy access to new animal health
    research concerning risk based and targeted
    surveillance
  • To develop risk based principles to optimise the
    use of resources
  • To contribute through horizon scanning to an
    updated picture of the threats as regards animal
    diseases.
  • To contribute to the Community Animal Health plan

19
Coordination of Veterinary Epidemiological
Research on Infectious Diseases in Europe (2)
  • Deliverables
  • To initiate multinational harmonised data
    collection, epidemiological studies and reporting
    of trans border diseases outbreaks
  • To develop and use modelling for animal diseases
    and surveillance to promote scenarios for the
    control including cost benefit of potential
    control measures.
  • To initiate research in sampling and survey
    methodologies including risk based principles in
    disease monitoring or surveillance in order to
    secure a more focused use of resources
  • To identify challenges including animal heath
    questions related to climate change to ensure
    European preparedness.

20
ETP Global Animal HealthAction Plan
  • 3.2. Establish a European Centre for Epidemiology
    and Infectious Animal Diseases.
  • SRA Recommendations. 21
  • Objective In Europe, epidemiological research is
    carried out in national institutions and is
    mainly organised and funded by the EU Member
    States. A central institution with coordinating
    responsibilities for fundamental and applied
    research in the field of infectious diseases and
    epidemiology is required. In view of the recent
    enlargement of the EU there is a requirement for
    an efficient infrastructure or centralised
    institution for fundamental and applied research
    into epidemiology and infectious diseases.
  • Deliverables
  • A scoping study of the options available for
    improving applied research into epidemiology and
    infectious diseases and the development of an
    appropriate infrastructure with responsibility
    for training epidemiologists to create a critical
    mass for the future
  • A report into the pros and cons of a virtual
    versus a physical centre
  • The implementation of the most appropriate option
    either the establishment of a specific or a
    virtual European Central Institution for
    Epidemiology and Animal Infectious Diseases.
    Alternatively a fully funded community reference
    laboratory could be established. The centre to
    act as a repository for a range of databases on
    disease information.
  • Availability of a budget for the centre whether
    virtual or physical

21
ETP Global Animal HealthAction Plan
  • Tasks for European Centre for Epidemiology and
    Infectious Animal Disease
  • Development of knowledge along the entire animal
    health chain, e.g.- research in the area of
    interaction between epidemiology and infection
    biology focussed on the development of
    integrated control strategies- integration of
    innovation by research groups with development of
    vaccines and diagnostics by the pharmaceutical
    industry - policy support of governmental
    bodies in the fields of prevention and control.
  • Development of risk assessment models
  • Data mining techniques to be developed and
    implemented
  • Reference Centre for education and training,
    particularly in the field of epidemiology.
  • Integration of research with research centres for
    human infectious diseases.
  • Management of a common European database for
    surveillance and early warning.
  • Initiation of joint research programmes and
    exchange of expertise with centres in developing
    countries, in particular the source countries for
    (re)emerging infectious diseases (i.e. twinning)

22
ETP Global Animal HealthDanish Proposals and the
Action Plan
  • Endemic diseases.
  • Objective
  • To develop a broader scientific approach to
    welfare threatening diseases
  • Deliverables
  • Multidisciplinary approach to causes and best
    intervention strategies
  • Explore links between immunity development,
    pathogenesis and epidemiology to areas such as
    business and animal health economics, animal
    ethics and sociology
  • Explore from the welfare perspective as opposed
    to production perspective
  • Define welfare spanning farmer and consumer

23
ETP Global Animal HealthDanish Proposals and the
Action Plan
  • Diseases in the Action plan.
  • In the Action plan the process was developed
    further with the result that 47 priority diseases
    in 3 groups were listed.
  • Group 1 Epizootic diseases and diseases for
    surveillance
  • Group 2  Zoonoses and food-borne diseases
  • Group 3 Major food-producing animal disease
    complexes

24
FP7 projects contributing to research
Group 1 Epizootic diseases and diseases for surveillance Vaccine Diagnostic Pharmaceutical Control Strategy Capacity building
African Horse Sickness  FP7  FP7    FP7  FP7 FP7
African Swine Fever   ASFRISK     ASFRISK  ASFRISK ASFRISK
Avian Influenza  FP6 FP6    FP6  FP6  FP6
Bluetongue  FP6/7   FP6/7     FP6/7   FP6/7 FP6/7
Contagious Bovine Pleuro Pneumonia          
Classical Swine Fever  CSFV GoDIVA   CSFV GoDIVA     CSFV GoDIVA   CSFV GoDIVA CSFV GoDIVA
Foot Mouth Disease  Discovac  Discovac      Discovac   Discovac  Discovac
Peste des Petits Ruminants          
Rift Valley Fever    ARBOZOONET     ARBOZOONET    ARBOZOONET
Ruminant Pox Virus infection          
Swine Vesicular Disease          
West-Nile Virus    ARBOZOONET     ARBOZOONET    ARBOZOONET
25
Group 2  Zoonoses and food-borne diseases Vaccine Diagnostic Pharmaceutical Control Strategy Capacity building
Anthrax
Nipah virus infection
Bovine Tuberculosis ICONZ TB_STEP ICONZ TB_STEP ICONZ TB_STEP ICONZ TB_STEP
Brucellosis ICONZ ICONZ ICONZ ICONZ
Chlamydia
Cryptosporidium
Cysticercosis ICONZ ICONZ ICONZ ICONZ
Echinococcosis ICONZ ICONZ ICONZ ICONZ
Food-borne bacterial Salmonella E. Coli Campylobacter FP7 FP7 FP7
Food-borne viral (Hepatitis E Virus
Leishmaniasis ICONZ ICONZ ICONZ ICONZ
Leptospirosis
Q Fever
Rabies ICONZ ICONZ ICONZ ICONZ
Trypanosomiasis ICONZ ICONZ ICONZ ICONZ ICONZ
Transmissible Spongiform Encephalopathies
26
FP6 and FP7 projects contributing to research
Group 3 Major food-producing animal disease complexes Vaccine Diagnostic Pharmaceutical Control Strategy Capacity building
Parasitic gastro-intestinal diseases Liver Fluke Coccidiosis Nematodes FP7/10 FP7/10 FP7/10 FP7/10 FP/10 FP7/10
Paratuberculosis (Johnes)
Mastitis  Staph.aureus mastitis Environmental/Streptococcal mastitis Small ruminant mastitis
Respiratory Swine PRRS CG3 HN PCV II SIV A. pleuropneumonia Mycoplasma FP7/09 FP7/09 FP7 2009 FP7/09 FP7/09 FP7/09
Respiratory Bovine BVDV BRSV BHV-I (IBR) Mycoplasma
27
ETP Global Animal HealthAction Plan
Theme 3 Fundamental Science Theme 3 Fundamental Science Theme 3 Fundamental Science Theme 3 Fundamental Science Theme 3 Fundamental Science
No Item Status Project title Comment
3.1 Support and Strengthen Fundamental Sciences in the EU Partial ongoing various A number of FP7 projects target research to areas of fundamental science A European Academic Network for Vaccine Research
3.2 Establish a European Centre for Epidemiology and Infectious Animal Diseases. To commence No action taken Coordination of Veterinary Epidemiological Research on Infectious Diseases in Europe
3.3 i ii iii iv v Specific Requirements for Fundamental Research Host pathogen interaction Fundamental immunology Epidemiology Genomics Bio-informatics. (i) ongoing (ii) To be commenced MACROSYS Macrophage systems biology applied to disease control A European Academic Network for Vaccine Research
28
Ideas to be transformed into research projects
  • Outline of the Presentation.
  • Introduction
  • The Action Plan
  • Danish Proposals
  • Funding of Proposals
  • Conclusions

29
ETP Global Animal HealthAction plan Funding
  • Sources of funding for the proposals
  • EC Programs (e.g. FP7, COST, DGs)
  • Close consultation with EC, MSs, EP
    representatives
  • National research programs- EMIDA
  • Providing opportunities to better align and
    coordinate national programs. (EMIDA ERA-Net),
    SCAR
  • Public/private research partnerships
  • Exploring areas of strategic importance in which
    ambitious initiatives can be taken
  • Charities and private non-profit foundations .
  • All these funding bodies have their own
    agendas/priorities that are set independently of
    each other)

30
EC Funding Framework 7 Programme 2007 to 2013

Cooperation Collaborative research 32.342b
(1.944)
Ideas Frontier Research 7.460b
People Human Potential 4.728b
Capacities Research Capacity 4.243b
  • Cooperation is 64 of budget of FP 7 budget of
    50.524 billion
  • Food, Agriculture Biotech - 1.944b

31
Cooperation Collaborative research
Joint Technology Initiatives
Collaborative research (Collaborative projects
Networks of Excellence Coordination/support
actions)
Coordination of non-Community research
programmes (ERA-NET ERA-NET Article 169)
International Cooperation
Small collaborative projects (small or
medium-scale focused research actions) are
projects with a requested Commission contribution
up to 3 million Large collaborative projects
(large-scale integrating projects) and Networks
of Excellence between 3 million and 6
million Coordination and Support Actions (CSA)
up to 1 million
32
Cooperation Collaborative research
Calls made Call FP7-KBBE-2007-1 Publication
Date 22/12/2006 Deadline 02/5/07 ERA Net,
discontools, BTb, ASF, RVF, WNF, CCF FP7-
KBBE-2007-2A Publication Date 15/6/2007,
Deadlines 11/9/07 stage 2 19/2/08 - Stage 2
(only for proposals retained at stage 1
Wildlife, ICONZ, zoonoses FP7- KBBE-2008-2B
Publication Date 30/11/ 2007 Deadline 26/2/
2008. FMD, CSF FP7- KBBE-2009-3 Publication
Date 03/9/2008 Deadline 15/1/ 2009 PRRS,
Orboviruses, Tick borne diseases,
campylobacter FP7-KBBE-2010-4 Publication Date
30/7/2009 Deadline 14/1/2010 Swine influenza,
Parasites,welfare
33
FP7 KBBE-2010-4
Activity 2.1 Sustainable production and management of biological resources from land, forest and aquatic environments Activity 2.1 Sustainable production and management of biological resources from land, forest and aquatic environments Activity 2.1 Sustainable production and management of biological resources from land, forest and aquatic environments
Area Topics called Funding Schemes
2.1.3 KBBE.2010.1.3-01 Development of vaccines and improvement of detection systems to control helminth parasite infections of livestock and reservoirs SICA (Latin America and/or Asia and/or African Mediterranean Partner Countries and/or African ACP) Collaborative Project (large- scale integrating project) for Specific Cooperation Actions Dedicated to International Cooperation Max. EC contribution/proposal EUR 9 000 000
2.1.3 KBBE.2010.1.3-02 Promoting coordination and cooperation at international level of research programmes in the area of animal health, in particular infectious diseases including zoonoses - Mandatory ICPC (Latin America and Asia) Coordination and Support Action (coordinating action) Max. EC contribution/proposal EUR 1 000 000
2.1.3 KBBE.2010.1.3-03 Development and integration of animal based welfare indicators in livestock species Collaborative Project (large scale integrating project) Max. EC contribution/proposal EUR 4 500 000
2.1.3 KBBE.2010.1.3-04 Improving integration in farm animal welfare research in an enlarged Europe Coordination and Support Action (coordinating action) Max. EC contribution/proposal EUR 1 000 000
KBBE.2010.1.3-05 Swine influenza surveillance network Coordination and support action (coordinating action) Max. EC contribution per proposal EUR 1 000 000 Maximum one proposal can be selected.
KBBE.2010.1.3-06 Pathogenesis and transmission of influenza in pigs (CP-IP) Collaborative project (large scale integrating project32) Max. EC contribution per proposal EUR 5 000 000 Maximum one proposal can be selected
34
EC Funding Framework 7 Programme 2007 to 2013

Cooperation Collaborative research 32.342b
(1.944)
Ideas Frontier Research 7.460b
People Human Potential 4.728b
Capacities Research Capacity 4.243b
  • Cooperation is 64 of budget of FP 7 budget of
    50.524 billion
  • Food, Agriculture Biotech - 1.944b

35
Capacities Research Capacity
36
EC Funding COST Programme
  • COST together with EUREKA and the EU framework
    programmes is one of the three pillars of joint
    European research initiatives. These three
    complementary structures have differing areas of
    research.

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EC Funding Framework 7 Programme 2007 to 2013
  • The ERA-NET scheme was introduced under FP6 to
    support the networking of research funding
    organisations (programme owners and managers e.g.
    government ministries and research councils) to
    develop and strengthen the coordination of
    national research programmes.
  • KBBE-2007-1-3-02 Coordination of European
    research in the area of animal health, including
    emerging threats, infectious diseases and
    surveillance. ERA-Net (SRA 13,35,37,47) (1m) 3
    years 1/4/08

43
Member State Funding
  • EMIDA ERA-NET
  • Coordination of European research in the area of
    animal health, including emerging threats,
    infectious diseases and surveillance
  • 26 partners in 19 countries and four associated
    partners
  • Combined research budget in the region of 270
    million Euros

44
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Aims of EMIDA
  • The overall aim of the Animal Health ERA-NET is
    to build on and accelerate the work of the SCAR
    CWG in developing a durable focused network of
    national research funders in Member and
    Associated States of the EU for the purpose of
    sharing information, coordinating activities and
    working towards a common research agenda and
    mutual research funding activities in the field
    of animal health.

46
Scope of EMIDA
  • The scope of the project will include emerging
    and major infectious diseases of production
    animals, including fish and bees and including
    those conditions which pose a threat to human
    health but excluding food safety issues relating
    to livestock products and diseases of wildlife,
    except where they act as a reservoir of infection
    for humans and animals.

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48
Transnational Calls from EMIDA
  • Vectorborne diseases - Development of
    underpinning knowledge and tools for early
    warning, detection monitoring and novel control
    strategies
  • Zoonoses and antimicrobial resistance, excluding
    microbial safety of products - Development of
    underpinning knowledge and tools for early
    warning, detection monitoring and novel control
    strategies
  • Major infectious diseases affecting production
    Development of underpinning knowledge and tools
    for early warning, detection monitoring and
    novel control strategies, including genetics of
    resistance
  • Aquaculture - Development of underpinning
    knowledge and tools for early warning, detection
    monitoring and novel control strategies,
    particularly vaccine-based approaches

49
Transnational Calls from EMIDA
  • Pre-announcement flyer www.EMIDA-ERA.NET
  • Formal Announcement 21 July
  • Call opens 7 September
  • Pre-proposal Submission deadline
  • 16 November
  • Invitation for full proposals 23 December
  • Deadline for full proposals 1 March
  • Funding decisions June 2010

50
Ideas to be transformed into research projects
  • Outline of the Presentation.
  • Introduction
  • The Action Plan
  • Danish Proposals
  • Funding of Proposals
  • Conclusions

51
ConclusionsDanish Proposals and the Action Plan
  • Proposals
  • A European Academic Network for Vaccine Research
  • Coordination of Veterinary Epidemiological
    Research on Infectious Diseases in Europe
  • Endemic diseases
  • Action plan
  • Components in the action plan, 3.1,,3.3,4.1
  • Recommended in the action plan, 3.2
  • Apart from MUMS not in the action plan

52
ConclusionsDanish Proposals and the Action Plan
  • Proposals
  • A European Academic Network for Vaccine Research
  • Coordination of Veterinary Epidemiological
    Research on Infectious Diseases in Europe
  • Endemic diseases
  • Funding
  • COST
  • FP7 Collaboration
  • COST
  • EMIDA

53
Conclusions.
  • To be successful any proposals must-
  • Reinforce leadership at international level,
    increase international cooperation
  • Early involvement of industry, SMEs
  • Contribute to the
  • EU Animal Health Strategy
  • Development policy and MDGs
  • Action Plan ETPGAH

54
Mirror groups
55
  • THANK YOU

56
COST National Coordinators (CNC)
  • Mr Gorm Bramsnæs
  • Country representative for Denmark
  • Ministry of Science, Technology and
    InnovationBredgade 40 DK-1260 Copenhagen K
    Denmark Tel. 45 3544 6343Fax 45 3544
    6201gbr_at_fi.dk
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