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... research institutions in predictive pharmaco-toxicology. ... Core competences in predictive pharmaco-toxicology. Expertise. Liver pathology and biology ... – PowerPoint PPT presentation

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Title: Mission%20statement

Mission statement
  • Austrian biomedical research institutions intend
    to assume leadership within the IMI. This will be
    achieved by a double-pronged strategy
  • Positioning and developing of core competences of
    Austrian research institutions in predictive
  • Proposal to EC of a framework and roadmap of the
    ECDS as an integrated network by identifying
    appropriate partners with complementary expertise
    and by defining their interfaces.
  • This strategy will enable Austrian researchers to
    make a valuable contribution to the enhancement
    of European competitiveness in drug development
    and to benefit from increased networking and
    acquisition of funding.

Potential additional benefits
  • Hosting the headquarter of the ECDS
  • Increased public awareness at national and
    European levels
  • Improved training possibilities and better
    qualified personnel
  • Fostering existing and future PPPs and
    academia-industry partnerships in Austria

Core competences in predictive pharmaco-toxicology
  • Expertise
  • Liver pathology and biology
  • Toxicology
  • Technology
  • Drug proteomics (off-target effects)
  • Tissomics (biomarkers)
  • Metabolomics (biomarkers)
  • In silico models
  • Assets
  • Biobank (biomarkers)

Next steps
  • Internal
  • Summary of discussion (Zatloukal)
  • National
  • Funding for consortium formation (BMBWK, FFG,
    ABI, RFT) (Herlitschka)
  • Mouse models (Müller)
  • Metabolomics (Biocrates)
  • International
  • EMEA (Eichler)
  • Pharmacovigilance (Eichler)
  • In silico (e.g. Astex Superti-Furga, Tripos
    Hecht, IMGuS Zatloukal, Gramatica
  • CYPs (Wolf Schulte-Hermann)
  • EU
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