Contact activation intrinsic pathway PowerPoint PPT Presentation

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Title: Contact activation intrinsic pathway


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Contact activation (intrinsic) pathway
Tissue factor (extrinsic) pathway
Damaged surface
Trauma
Tissue factor
XII XIIa
VIII
VIIa VII
XI Xia
Tissue factor
Trauma
IX IXa
VIIIa
Antithrombin
X
X
Xa
Common pathway
Prothrombin (II)
Thrombin (IIa)
Va
Activated Protein C
Fibrinogen (I)
Fibrin (Ia)
V
Protein S
XIIIa XIII
Protein C
Cross-linked fibrin clot
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