The Centre for Process Innovation

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The Centre for Process Innovation Wilton, Redcar
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The Strategy for Success
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Features of the CPI vision

• A National Resource
• World-class, internationally recognised
• Regional and UK Plc agenda
• Scope - base, speciality, fine, pharmaceuticals,
  downstream
• Collaborative applied research and development
• Market/Industry led
• Incremental build of skills, knowledge,
  facilities and capability
• Multi-company or one-on-one
• Manufacturers
• Catalyst producers
• Technology developers/suppliers
• Universities regional, national and international

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So ..

• Were here to reduce the barriers to innovation
  by
• sharing risk, providing facilities, resources,
  and knowledge
• Were a company limited by guarantee
• we cant make and distribute a profit
• We do not provide money
• Were not a government grant agency
• Were about actionwere here to do things
• With confidentiality assured
• We want a (small) share of the action
• To cover costs and make us self-sustaining
• We recruit the Best Talent available
• Work as a Team

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Strong Industry Involvement
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How CPI works
Industry/Market Demand
Demand
Advanced Processing Manufacturing
Thrusts
Functional Materials
Platforms
Supercritical Fluids
Electronic Polymers
Company n
Company
Collaborators
Programmes
Science Base
Universities
Technology Advisory Committee oversees agenda
and advises on relevance and quality
Academic links will be stimulated by
part-sponsorship of chairs/post-docs/joint
programmes
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Fuel Cell Applications Facility

• Objective create a fuel cells cluster in the
  Tees Valley
• Static applications
• Supply security and fuel efficiency main drivers
• Demonstrator projects
• Significant Involvement
• DuPont, Huntsman, Johnson Matthey, BOC, Air
  Products, Terra Nitrogen, Norsk Hydro, Black
  Decker
• Intelligent Energy, Fuel Cells UK, DTI, Carbon
  Trust, Canadian Research Council, US Department
  of Energy
• Progress is substantial
• 3 demonstrators in place, 2 more planned
• Targeting 2.8bn European funding

enabling a supply chain
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Polymer Electronics

• Collaboration with DuPont Teijin Films
• Initial project on the Functional Materials
  Platform
• Objective is to develop luminescent polyester
  films for displays
• Disruptive Technology
• Development facility at CPI
• Progress
• xm project
• DTF/CPI contract executed
• Potential consortium members
• Xaar, Avecia, ICI, DuPont Teijin, Du Pont
  Displays, Kodak, Plastic Logic, Cambridge
  Displays, Philips, University of Durham
• UK Plastic Electronics Manufacturing Facility
  potential

Building a new industry
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Functional Materials Platform

• Focused on developing new products
• Significant number of opportunities
• Challenge is not to get distracted!
• Many companies interest in molecular level
  effects but common agenda needs to be defined
• Advanced Functional Materials Centre Proposal
• xM application to DTI
• xM matched by Industry
• Links with University of Durham, White Rose
  Nano-factory and others

Exploiting material properties
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Business Development

• Offers leading edge support and Technology
  Transfer to industry
• Facilitating improvement by sharing Best Practice
• Pilot plant equipment brokerage
• Specialist consultancy services
• Direct support to 40 SMEs
• Relationships with Universities
• Possible sponsorship of chairs
• Newcastle for Chemical Engineering
• Durham for Chemistry
• Encouraging collaborations between Universities
• Interdisciplinary Research Centre in Polymer
  Science
• Support to spin-outs and start-ups

leveraging knowledge
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Bio-Processing

• Centre of Excellence in Bio-catalysis,
  Bio-transformations and Bio-catalytic
  Manufacturing CoEBio3
• Focused on high value fine chemicals and
  pharmaceutical intermediates
• Pro-Bio, EPSRC and DTI supported initiative
• led by Prof Roberts from University of Manchester
• 20m project over 5 years
• Core academic research at Manchester plus York
  Heriot-Watt
• 2.5m capital pre-manufacturing scale up facility
  at CPI
• 20 companies interested including
• AstraZeneca, GSK, Johnson Matthey, Angel Biotech,
  BASF
• 15 already signed up as of 01/12/04

developing new ways to make things
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Supercritical Fluids Processing

• A new processing route
• Enables highly selective chemistry
• Of interest to control particulate formulation
• Novel process fluid e.g. water
• Can be used to make a wide range of molecules
• Developing collaborative project with several
  companies, Nottingham University, Newcastle
  University and others
• Pre-competitive generic development creating
  IPR for the partners
• Initial programme focusing on water
• xm project
• Future one-to-one programmes with other
  collaborators catalysis, hydrogenation

developing new ways to make things
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Batch to Continuous Processing

• Significant opportunity
• Cost pressures as margins squeezed
• Process Analytical Technology (PAT) Initiative
  brings whole pharmaceutical industry into play
• 4 consortia running or being established
• 5 companies working together with a university
  based technology for novel reaction systems
• Several companies coming together with CPI to
  look at heat-exchange reaction systems
• Bioreactor consortium is under development
• A consortium is under development to look
  continuous precipitation and crystallisation
  options

developing new ways to make things
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Advanced Processing Platform

• Focused on manufacturing routes
• More with less increase capital intensity and
  variable cost efficiency
• Increasing speed of development of new processes
• Only making the molecules you want reducing
  by-products
• Green processing
• Vision is to systematically create a
  multi-purpose demonstration capability
• 8020 concept non-optimised, proof of concept
• Multiple feedstock and types
• Reaction system options coupled with separation
  purification

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Business Intensification by Advanced Processing
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Business Intensification by Advanced Processing
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Business Intensification by Advanced Processing
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Speeding the adoption of new technologies

• Develop and demonstrate putative processes
• Produce trial quantities of product
• Demonstrate whole process
• Assess and mitigate commercial case and risk

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Thank You