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Research and Education

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Young Life Research Clinic: Institute of Natural Medicine ... James A. Duke Ph.D database:ars-grin.gov/duke/ NAPRALERT database: http://stneasy.cas.org ... – PowerPoint PPT presentation

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Title: Research and Education


1
Research and Education
CANCeR
  • Contact Peter F. Minke Ph.D.

Young Living Essential Oils 3125 West Executive
Parkway Lehi, Utah 84043
2
Resources
  • Young Life Research Clinic Institute of Natural
    Medicine
  • Food and Drug Administration www.fda.gov
    (multiple sites)
  • National Cancer Institute (NCI)
    http//cis.nci.nih.gov
  • Office of Dietary Supplements (ODS)
    http//dietary-supplements.info.nih.gov/
  • James A. Duke Ph.D databasears-grin.gov/duke/
  • NAPRALERT database http//stneasy.cas.org

3
Traditional Information
  • Hartwell, J.L. (1969-1979)
  • Plants Used Against Cancer. A Survey
  • Lloydia 30-34
  • A classic treatise on the reports of
    historical use of plants against cancer

4
Cancer Research (Ponce School of Medicine)
  • Academic collaboration with Young Living
    Essential Oils
  • Investigation of the anti-cancer activity of
    essential oil of frankincense
  • Investigation of the effects of various essential
    oils on cellular DNA repair

5
In Vitro Effects of Frankincense on Cancer Cells
  • In vitro growth inhibition assay cancer cells
    (breast cancer cell line MCF-7) growing in
    culture conditions are introduced to various
    concentrations of frankincense essential oil for
    24 hrs. and growth inhibition is measured by
    evaluating cell proliferation.
  • The results (repeatable) are biphasic showing
    either an inhibition or stimulation of cell
    proliferation depending on the concentration of
    frankincense oil in the growth media.
  • Maximal growth inhibition occurs at 50 mg/ml
    (65 average reduction in cell number) and 200
    mg/ml (40 average reduction in cell number) of
    frankincense oil in culture media.
  • Growth stimulation (less than 10 average
    increase in cell number) occurs at 100 mg/ml.
  • Flow cytometry studies to evaluate the cause of
    cell number reduction (by necrosis or by
    apoptosis) are inconclusive.
  • Next steps for Young Living Essential Oils
    Clinical studies in which frankincense oil is
    administered in repeated small doses to achieve a
    low sustained physiological concentration in the
    target tissue are in the planning stages.

6
Essential Oils and DNA Repair
  • The ability of cells to repair damage to DNA
    caused by toxins, radiation, or other stressors
    is vital to the health of the individual.
  • DNA repair in cultured lymphocytes has been shown
    to decrease with the age of the donor and is
    dramatically reduced in people with cancer.
  • Efforts have begun to screen essential oils for
    effects on DNA repair in cultured lymphocytes.
    This work has the potential to link essential
    oils with health and longevity at a molecular and
    cellular level.

7
Current Research
  • Bioassay Analyses to Determine Anti-Cancer
    Activity of Essential Oils. Nicole A. Stevens,
    Masters Thesis, Brigham Young University.
    August 2002
  • Essential oils and support for research provided
    by Young Living Essential Oils
  • Anti-cancer activity (cancer cell toxicity) was
    evaluated for 74 essential oils using four cancer
    cell lines (breast, cervical, prostate, skin) and
    a control cell line

8
Key Findings-N.A.Stevens
  • 26 of the 44 active oils (59) are
    cancer-specific and should be considered for
    further study
  • These essential oils that have been used
    medicinally for centuries may prove to be a very
    valuable resource in our search for new cancer
    drugs

9
Current Research (Sabinsa)
  • Young Living scientists engaged in professional
    collaborations with Sabinsa Corporation
    scientists (see Sabinsa poster on Selenium)
  • FDA recognition of selenium for prevention and
    treatment of cancer (limited health claim)
  • Selenium is an ingredient in ImmuPro

10
Disclaimer
  • This poster was presented and written for the
    sole purpose of providing educational and
    research information on cancer. It is not
    designed, in whole or in part, as advice for
    self-diagnosis or self-treatment and should not
    be construed as such. Young Living does not
    promote or endorse the treatment of cancer with
    Young Living products.

11
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