Robin Clark, Director

1
Welcome
Bioinformatics for Cancer Research

• Robin Clark, Director
• NCRI Informatics Coordination Unit

2
Cancer
3
(No Transcript)
4
Cancer
DNA
Environment
Diagnostics
Functional genomics
Imaging
Proteins
Therapeutics
Pathways
Psychosocial interventions
Cells
Clinical trials
Tissues
Population studies
Organs
Model systems
Whole person
5
NCRI Informatics principles

• Coordination and collaboration
• Promote interoperability
• UK and internationally
• Provide some underlying infrastructure
• Software open and free at the point of use
• Advertise and promote standards
• But not write them!
• Change culture
• to one of data sharing being the norm

6
NCRI Informatics Coordination Unit Working with
and for the community

• Categorising and cataloguing standards
• Maintaining and promoting the matrix
• Hosting workshops (Examples)
• Data Sharing
• Genetic variation
• Presentations at external events
• For example caBIG Annual Meeting, LRF, Wellcome
  Data to Discovery meeting, UCL public lecture
  series, etc
• Sample Conferences and Publications (2007)
• Joint UK/US Informatics Conference
• Cancer Informatics, Nature Biotechnology, Human
  Mutation
• Demonstrator Projects
• Community engagement
• Helping to identify new funds for the community
• Coordinating Informatics Platform development
• Fully subscribed for early adopters to NCRI
  Informatics Platform

7
What is The Platform?
8
Status of the Platform Implementation Plan

• Approved by NCRI Informatics Management Board
• Late 2006
• Activities commenced January 2007
• Phase I on schedule for release end 2008
• Is already a collaborative effort extending
  outside NCRI
• Goal is to be interoperable with US caBIG
• Focus will be on resource discovery
• Prototype available now to help elicit feedback
  from user groups
• Phase II planned for end Q1, 2010
• Progress formally assessed at NCRI Informatics
  Management Board Gate Reviews
• Most recent in June 2007

9
Summary

• The NCRI Informatics Initiative is helping
• To work with the UK and international community
  to build re-usable infrastructure
• To change culture to make the infra-structure
  usable
• To make impact of individual projects even more
  effective
• We think it is in everyones best interest
• But our approach is open and voluntary

10
(No Transcript)