Title: VFD standard skabelon
 1 Campylobacter Risk Assessment in Poultry
Helle Sommer, Bjarke Christensen, Hanne 
Rosenquist, Niels Nielsen and Birgit Nørrung 
 2Probability of Exposure
P r e v a l e n s
Pfarmh.
SLAUGHTERHOUSE
RETAIL
CONSUMER
RISK
Ca.bleeding
C o n c e n t r a t i o n
Probability of Infection 
 3 Slaughter house modules
-  Data examinations  distributions 
 -  Process model building  explicit equations 
 -  Explicit equations/ simulations 
 -  Cross contamination 
 -  What-if-simulations
 
  4Data examinations
-  Data for 3 different purposes 
 -  - prevalence distribution -gt slaughterhouse 
program  -  - concentration distribution 
 -  - model building, before and after a process
 
-  From mean values to a distribution
 
-  Lognormal/ normal gt illustrations
 
-  Same or different distributions gt variance 
analysis 
  5From mean values to a distribution
17 log mean values from different flocks and from 
2 different studies 
 6From mean values to a distribution
17 distributions -gt one common distribution 
 7Log-normal or normal distribution ?
True data structure  simulated data 
(sim.) Assumed distribution (dist.) Published 
data  means of 4 samples,6 means from one 
study sim. lognormal(6.9,2.3) dist. normal or 
lognormal 
 8(No Transcript) 
 9(No Transcript) 
 10(No Transcript) 
 11Real data set 
 12New Danish data 
 13Building mathematical models
Slaughterhouse process  
 14Why new mathematical process models ? 
 15Explicit mathematical process model 
 16Explicit mathematical process model
In normal scale µy  µx / ?µ 100  10000/100 In 
log scale µlogy  µlogx  ?µ 2  4 - 2 
 17Explicit mathematical process model
In normal scale µy  µx / ?µ 100  10000/100 In 
log scale µy  µx  ?µ 2  4 - 2 sy2  ß2  sx2 
Transformation line y  ?  ßx 
 18Explicit mathematical process model
Overall model µy  µx - ?µ sy2  ß2 sx2 Local 
model Y  ?  ßx
Calculation of ? ?  (1-ß) µx- ?µ  
 19Explicit mathematical process model
In normal scale µy / µx  158 In log scale µy  
µx - 2.2  
 20Explicit mathematical process model
In normal scale y  x  z z ? N (µ, s) 
 21Summing up 
-  Data  knowledge/logical assumptions of the 
process -gt multiplicativ or additive process  
-  Explicit equations for modelling slaughterhouse 
processes  Monte Carlo simulations, modelling 
each chicken with a given status of infection, 
concentration level, order in slaughtering, etc.  
-  New data of concentration (input distribution) 
-gt different or same distribution ? (mean and 
shape) 
  22Advantage with explicit equations 
-  Faster than simulations/Bootstrap/Jackknifing 
 
-  Accounts for homogenization within flocks 
 
-  More information along the slaughter line does 
not give rise to more uncertainty on the output 
distribution.