Bipolar Depression: OFC MADRS Item Analyses

1
Bipolar DepressionOFC MADRS Item Analyses
Source

Apparent sadness
Review

Reported sadness

Inner tension


Reduced sleep


Olanzapine fluoxetine
Reduced appetite

Olanzapine
Reviewer Memo
Placebo
Concentration difficulties

Lassitude

Inability to feel

Pessimistic thoughts
Suicidal thoughts
-3.0
-2.5
-2.0
-1.5
-1.0
-0.5
0.0
P lt .05 Olanzapine vs placebo P lt .05 OFC
vs placebo P lt .05 OFC vs Olanzapine Tohen MF
Jr, et al. Arch Gen Psychiatry.
2003601079-1088. Erratum in Arch Gen
Psychiatry. 20046176.
Mean Change From Baseline MADRS Items (LSM)
Slide Modified
Memo