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Lithium A Doctor, a Drug, and a Breakthrough
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Lithium A Doctor, a Drug, and a Breakthrough
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Description
From insulin comas and lobotomy to incarceration
and exile, Walter Brown chronicles the troubling
history of the diagnosis and (often ineffective)
treatment of bipolar disorder through the
centuries, before the publication of a
groundbreaking research paper in 1949.
Cade's quotLitium Salts in the Treatment of
Psychotic Excitementquotdescribed, for the first
time, lithium's astonishing efficacy at both
treating and preventing the recurrence of
manic- depressive episodes, and would eventually
transform the lives of patients,
pharmaceutical researchers, and practicing
physicians worldwide. And yet, as Brown shows, it
would be decades before lithium would overcome
widespread stigmatization as a dangerous substance
, and the resistance from the pharmaceutical
industry, which had little incentive to promote a
naturally occurring drug that could not be
patented.Brown also provides a vivid portrait of
the story's unlikely hero, John Cade, a devoted
naturalist who, unlike many modern medical
researchers, did not benefit from prestigious
research training or big funding sources. In this
revelatory biography of a drug and the man who
fought for its discovery, Brown crafts a
captivating picture of modern medical history -
revealing just how close we came to passing over
this extraordinary cure.