Epidemiology of ABPA | Jindal Chest Clinic

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Epidemiology of ABPA
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ABPA prevalence

• Prevalence of ABPA quoted as 1-2 in asthma and
  2-15 in cystic fibrosis in most reviews
• Two unpublished questionnaire-based surveys and
  one published study
• Ireland study - catchment area of 0.5 million -
  14 patients with ABPM in 1390 referrals - period
  prevalence of 1 Donnelly et al. Ir J Med Sci
  1991 160 288290

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ABPA prevalence

• Two questionnaire based studies
• Orange County, California - 2.4 million people -
  143 cases of ABPA
• AAAAI survey - survey among members of the
  academy - 703 ABPA Novey et al. Immunol Allergy
  Clin North Am 1998 18 641653
• Both of the above surveys in the US - total ABPA
  in 1991 to be around 11,000 (total population -
  260 million) - 1 of the estimated 12 million
  asthma patients in the US

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Our experience

• 755 patients screened (Aspergillus skin test)
• Aspergillin hypersensitivity 291 (38.5)
  patients
• ABPA - 155 patients (20.6)
• Serologic ABPA 37 (23.9) patients
• ABPA with CB 118 (76.1) patients

Agarwal et al. Chest 2006 130 442-448 Agarwal
et al. Chest 2007 132 1183-1190
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Prevalence of ABPA in asthma
Agarwal et al. Int J Tuberc Lung Dis 2009 13
936944
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Aspergillus hypersensitivity in asthma
Agarwal et al. Int J Tuberc Lung Dis 2009 13
936944
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ABPA in asthma
Agarwal et al. Int J Tuberc Lung Dis 2009 13
936944
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ABPA in aspergillus hypersensitivity
Agarwal et al. Int J Tuberc Lung Dis 2009 13
936944
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