Title: Latest Drug-Related Developments in Global Dry Eye Disease Market
1Latest Drug-Related Developments in Global Dry
Eye Disease Market As per a study on the
incidence and prevalence of dry eye disease in
the United States, the dry eye disease (DED)
prevalence was 5.28 overall, with 2.96 male
beneficiaries and 7.78 female beneficiaries.
According to another study on the economic burden
of dry eye disease in the United States, DED
incurred 55.4 billion in costs annually. Our
predictions project that the global eye disease
market growth is estimated to progress at a CAGR
of 5.11 during 23-32 and garner 8884.34 million
by 2032. As a result, drugs designed with
specific DED indications are ushering in a new
era in dry eye disease management.
- This blog focuses on some of the recent strategic
developments related to dry eye disease drugs. - OptiLight by Lumenis
- On 29th April 2021, Lumenis Ltd announced the
grant of FDA approval for its newest intense
pulsed light (IPL) device. - Subsequently, Lumenis launched OptiLight, a
bright solution for dry eyes. - Intense pulsed light (IPL) therapy is a new
treatment for rosacea and evaporative dry eye.
Meibomian gland dysfunction (MGD) increases the
severity of dry eye disease (DED) and can
clinically impact the patients quality of life.
Intense pulsed therapy (IPL) can benefit dry eye
by enhancing the dysfunction of the meibomian
glands.
2- OptiLight is patented with Lumenis OPT
technology and is designed for a controlled,
precise, and consistent light-based treatment of
dry eye disease. - Dr. Steven J. Dell, the lead investigator in the
Lumenis clinical trial for the FDA and medical
director of Dell Laser Consultants, said, We
deal with dry eye every day, but unless we
address the underlying inflammation, its
difficult to meaningfully impact the disease.
OptiLight helps us to address the inflammation,
as shown in Lumenis IPL clinical trials, and
improves signs of dry eye disease due to MGD,
positioning it as a valuable tool in our dry eye
toolkit. (Source) - Kala announces to sell INVELTYS and EYSUVIS
- On 23rd May 2022, Kala Pharmaceuticals announced
its entry into a definitive agreement to sell its
intellectual property assets and commercial
portfolio to Alcon Inc. This entails INVELTYS, a
corticosteroid for treating post-operative pain
and inflammation following ocular surgery.
Alongside EYSUVIS, the first and only United
States Food and Drug Administration
(FDA)-approved medicine for the short- term
treatment of symptoms and signs of dry eye
disease. Kala will receive an advance payment of
60 million and be eligible for commercial-based
sales milestone payments. - Mark Iwicki, Chief Executive Officer and
Chairman, Kala, said, The sale of EYSUVIS and
INVELTYS is an important step as we execute on
our strategic plan and pursue our mission of
delivering innovative therapies that can address
significant unmet needs in ophthalmology.
(Source) - New Drug Application (NDA) for Reproxalap by
Aldeyra Therapeutics - On 7th February 2023, Aldeyra Therapeutics
announced the US Food and Drug Administrations
(FDA) approval for the New Drug Application (NDA)
for topical ocular Reporxalap. The company
develops innovative therapies designed to treat
immune-mediated diseases. The NDA is supplemented
by previously announced efficacy and safety
results from well-controlled and adequate
clinical trials. These encompass data for ocular
redness, Schirmer test 10 mm responder analysis,
Schirmer test, ocular redness, and ocular dryness
symptom score. - Reporxalap is a first-in-class investigational
new drug candidate for treating the symptoms and
signs of dry eye disease. In dry eye disease
patients, RASP (reactive aldehyde species) may
facilitate changes in tear lipid composition,
ocular redness, diminished tear production, and
ocular inflammation. - Accordingly, Reproxalap presents a differentiated
and novel approach for treating the symptoms of
dry eye disease. - As stated by Todd C. Brady, MD, Ph.D., President
and Chief Executive Officer
treatment of dry eye disease. (Source)
3- New Drug Application (NDA) for CyclASol by
Novaliq - On 24th October 2022, Novaliq announced the US
FDA approval of the New Drug Application (NDA)
for CyclASol. It is a novel anti-inflammatory
product for treating signs and symptoms of dry
eye disease. It is preservative-free due to the
novel carrier and contains no oils or
surfactants. It offers additional clinical
benefits like reduced visual disturbances and
enhanced tolerability. - According to Christian Roesky, Ph.D., CEO,
Novaliq, This is an exciting time for
ophthalmologists and optometrists and their
patients as we are one step closer to address
important needs and to better treat a serious
ocular surface condition affecting millions of
Americans. If approved, CyclASol would be a
highly potent but comfortable anti-inflammatory
therapy for patients with dry eye disease.
(Source) - Ongoing Research Development in Global Dry
Disease Market - As per several research investigations, dry eye
is a lifestyle disease, and most of the
population is vulnerable. Accordingly, there have
been ongoing research and developments related to
dry eye treatment and solutions. For instance,
European Dry Eye Network was established in
Europe under Horizon 2020. It is a platform for
the training and career development of 10
early-stage researchers (ESRs) in vision
sciences. Such platforms are predicted to enhance
research efforts for dry eye disease treatment,
subsequently influencing the global dry eye
disease - market growth.
- FAQs
- Which country has lucrative prospects in the
global dry eye disease market? - A China has lucrative prospects in the global
dry eye disease market. - What are the risk factors of dry eye disease?
- A As per global experts, the non-modifiable risk
factors of dry eye disease are age, connective
tissue diseases, Meibomian Gland Dysfunction,
Sjogren's syndrome, etc.