Single-use Bioreactors Market valued at ~$3.39 billion in 2021 and is expected to grow at a CAGR of 20% by 2026

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Single-use Bioreactors Market By Top Players
ABEC, Cellexus, Celltainer Biotech BV, Distek Inc.
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Single-use bioreactors are bioreactors that
utilize a disposable bag in place of a glass or
stainless steel culture vessel. For cell harvest,
media and buffer preparation, filtration,
purification, and viral inactivation,
pharmaceutical companies use it widely. The
Global Single-use Bioreactors Market valued at
3.39 billion (2021) is set to witness a healthy
growth rate of 20 in the next 5 years. The
introduction of large-scale single-use
bioreactors, rising demand from pharma companies,
CROs, and CDMOs, the expanding biologics market,
rising biopharmaceutical RD, and the advantages
of single-use bioreactors are some of the
technological advancements that are propelling
the global single-use bioreactors market. Due to
their Ability to Enhance Flexibility, Reduce
Investment Limit Operational Costs, Single-use
Bioreactors Have Become Established in Modern
Biopharmaceutical Processes One of the main
advantages of single-use bioreactors is their
increased flexibility. There is a growing trend
towards multi-drug facilities, which warrants the
production of different drugs using the same
facility with minimum time cost and top-notch
quality. Line clearance and cleaning validation
in such circumstances are key manufacturing
challenges to guarantee there is no carryover
from previous batches. Downtime limits the number
of batches produced in a given period.
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• Single-use bioreactors significantly lessen the
  amount of time required to get the bioreactor
  prepared for the subsequent batch. A line
  changeover with a stainless-steel bioreactor can
  take 6 to 10 hours and three weeks for a full
  product changeover while by using single-use
  bioreactors it is likely to take 2 hours for line
  changeover. If the manufacturing line is composed
  of all single-use components such as bags,
  filters, and connectors, the total time for
  product changeover can be 48 hours. Single-use
  bioreactors may cut downtime from two to three
  weeks to just 48 hours, which can have a big
  influence on a company's output.
• Some of the other key advantages of using
  single-use bioreactors are
• Elimination of validation issues as no cleaning
  process is required
• Lowers the risk of cross-contamination
• Reduces operating costs and capital investments
  (including space, labor requirements, and
  utilities)
• Single-use bags are scalable and can be adjusted
  to different volumes
• Simple installation
• Potential Time Savings for Highly Trained
  Personnel Another Key Benefit of Single-use
  Bioreactors
• Normally, drug development research, process
  development, and scale-up activities are
  performed by highly qualified and trained
  personnel. These individuals are involved in all
  phases of a study from early-stage research
  through to benchtop manufacturing. Before each
  trial batch is taken, stainless steel or glass
  benchtop bioreactors' individual components must
  be cleaned, put together, tested for leaks,
  sterilised, and cooled. However, the use of
  single-use bioreactors almost eliminates these
  steps, which allows scientists more time to focus
  on their developmental studies.

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Market _at_ https//meditechinsights.com/single-use-b
ioreactors-market/ Technological Advancements
Customer-Centric Approach A Key Factor
Bolstering the Single-use Bioreactors Market
Demand Commercially available single-use
bioreactors are robust and provide the
high-performance necessary for commercial
manufacturing of biopharmaceuticals. The growing
usage of single-use bioreactors from the lab to
the production scale has been facilitated by
significant developments in bioreactor design,
film technologies, stirring mechanisms, and
sensor systems. To cater to the changing needs of
the customers such as next-generation cell- and
gene-therapies and continuous bioprocessing,
suppliers of single-use bioreactors often work
closely with its customers, which in turn is
expected to fuel the demand for single-use
bioreactors. The uptake of single-use
bioreactors is mainly driven by the activity of
the different regions regarding the development
of new disease treatments and biosimilars. In
addition, existing production capacity comes into
play and company strategies regarding the
manufacture of clinical material. As the USA is
indeed leading in the field of developing
innovative treatments, we see a strong uptake of
single-use bioreactors, but Europe and Asia are
not far behind. - CEO, Leading Manufacturer of
Single-use Bioreactors, United States
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Introduction of Large-Scale Single-use
Bioreactors Set to Drive the Single-use
Bioreactors Market Traditionally, single-use
bioreactors were restricted in size due to
pressure challenges from the increased weight of
the liquid medium in larger volume bags with
2,000 L being the upper limit. As a result, bio
manufacturers who required higher volumes had to
use stainless steel tanks or run multiple systems
simultaneously. However, in the last years,
considering strong demand from pharmaceutical
companies and contract development and
manufacturing organizations (CDMOs), numerous
single-use bioreactor manufacturers have launched
large-scale single-use bioreactors which are
anticipated to drive the market growth in the
coming years. Aligned with this trend in March
2021, Thermo Fisher launched 3,000 L and 5,000 L
HyPerforma DynaDrive single-use bioreactors. It
is touted as next-level innovation in single-use
bioreactors with unmatched design, scalability,
and performance. The system provides improved
performance and scalability to larger volumes and
is suitable for fed-batch and perfusion
processes. Competitive Landscape Analysis of
Single-use Bioreactors Market Some of the key
players operating in the global single-use
bioreactors market are Sartorius Stedim Biotech,
Thermo Fisher Scientific, Danaher Corporation,
and Merck KGaA.
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• Other Players Operating in the Single-use
  Bioreactors Market are (Indicative List)
• ABEC
• Cellexus
• Celltainer Biotech BV 
• Distek Inc.
• GG Technologies Inc.
• GPC Bio, among others
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