Sperm quality improve by frequent ejaculation rather than abstinence

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Sperm quality improve by frequent ejaculation
rather than abstinence
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"Do we need to update IVF protocols to use semen
from shorter periods of abstinence?"
introduction Men have usually been advised to
limit sexual activity to increase the chances of
pregnancy. A new study suggests sperm quality and
pregnancy outcomes in IVF may be improved with
frequent ejaculation,
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Summary Research carried out Da Li et aVaimed to
determine the effects of a short period of
abstinence on the quality of ejaculated sperm, as
well as its effect on the pregnancy outcomes of
500 couples undergoing EVE Major molecular
differences were seen between samples of semen
depending on the duration of abstinence.
Ejaculates from short (1-3 hours) compared with
long (3-7 days) periods of abstinence showed
increases in motile sperm count, sperm vitality,
normal sperm morphology, acrosome reaction
capacity, total antioxidant capacity, sperm
mitochondria' membrane potential, high DNA
stainability and a decrease in the sperm DNA
fragmentation index (Plt0.05). Sperm proteomic
analysis showed 322 differentially expressed
proteins (minimal fold change of 1.5 or greater
and P lt 0.05), with 224 up-regulated and 98
down-regulated. These differentially expressed
proteins are profoundly involved in specific
cellular processes, such as motility and
capacitation, oxidative stress and metabolism.
Interestingly, protein trimethyllysine
modification was increased and butyryllysine,
propionyllysine and malonyllysine modifications
were decreased in ejaculates from a short versus
long abstinence (P lt 0.051 Finally, the rates of
implantation, clinical pregnancy and live births
from in vitro fertilization treatments were
significantly increased (by one-third in this
study) in semen samples after a short abstinence.
This study provides preliminary mechanistic
insights into improved sperm quality and
pregnancy outcomes associated with spermatozoa
retrieved after a short ejaculatory abstinence.
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Conclusion These results collectively suggest
that having more frequent sex produces sperm of a
better quality and increases the likelihood of a
successful pregnancy. Specifically, semen samples
collected after only one to three hours of
abstinence contained more motile sperm with a
higher reproductive potential than samples
collected after men who had abstained for three
to seven days.
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References Zi-Qi Shen, Bei Shi, Tian-Ren Wang,
Liao Liao, Xuejun Shang, Qi-fun Wu, Yi-Ming Zhou,
Tie-Feng Can, Qiang Du, Xiu-Xia Wang and Da Li.
Characterization of the Sperm Proteome and
Reproductive Outcomes with in Vitro Fertilization
after a Reduction in Male Ejaculatory Abstinence
Period. Molecular Cellular Protearnics August
20, 2018,mcp.RA117.000541 https//doi.org/10.1074
/mep.RA11 2000541
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Sourcehttps//www.indianfertilitysociety.org/fert
ility-news-october-2018-volume-3/
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