Scapho 150mg injection - PowerPoint PPT Presentation

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Scapho 150mg injection

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Secukinumab is a generic form of brand name scapho 150mg and scapho 150mg injection is a type of biological therapy which prevent the function of IL-17A proteins. – PowerPoint PPT presentation

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Title: Scapho 150mg injection


1
Scapho 150mg Injection Secukinumab Uses Side
effects
  • MILLION HEALTH PHARAMACEUTICALS

2
DESCRIPTION
  • Secukinumab is a generic form of brand
    name scapho 150mg and scapho 150mg injection is a
    type of biological therapy which prevent the
    function of IL-17A proteins. This activity alters
    the immune activity and inflammation which cause
    the symptoms of psoriatic arthritis.
  •  Scapho 150mg is used as prescription drug given
    by a doctor rheumatologist for adults with
    psoriatic arthritis and ankylosing spondylitis.

3
INDICATION
  • Scapho 150mg injection prescribed for the therapy
    of patients with following condition Plaque
    Psoriasis Psoriatic arthritis Ankylosing
    spondylitis

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MECHANISM OF ACTION
  • Secukinumab consist of human IgG1 monoclonal
    antibody whichcarefullyconnects to the
    interleukin-17A (IL-17A) cytokine and prohibits
    its concomitant with the IL-17 receptor. IL-17A
    is a naturally appearing cytokine included in
    normal inflammatory and immune responses.
    Secukinumab prevents the release of
    proinflammatory cytokines and chemokines.

6
PRODUCT DETAILS
  • Brand Scapho Ingredients SecukinumabStrength
    150mg Manufactured Novartis India
    LtdPackage 150mg in 1 vial

7
ADME
  • Absorption high plasma concentration for single
    dose is 6 days and weekly dosing for first month
    is 31-34 days Distribution volume of
    distribution is 7.1 8.6 in IV administration
    Metabolism Intracellular catabolism is the drug
    metabolized Elimination half-life is 22-31 days

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DOSAGE MANAGEMENT
  • Plaque Psoriasis Initial dose for the patients
    is given 300 mg SC at weeks 0, 1, 2, 3, and
    4 initially at week 8, given 300 mg SC once
    monthly The prescribed dose for plaque psoriasis
    is 150 mg may be acceptable for some patients

10
DOSAGE MANAGEMENT
  • Psoriatic Arthritis  The recommended dosage for
    Psoriatic arthritis for other patients,
    administer with or without a loading dosage by SC
    injection Scapho 150mg the recommended dose with
    loading dose administrated 150 mg SC at weeks 0,
    1, 2, 3, and 4 and q4wk thereafter Scaphothe
    recommended dose without loading dose
    administrated 150 mg SC q4wk. 

11
DOSAGE MANAGEMENT
  • Ankylosing Spondylitis The recommended dose is
    given with or without a loading dosage by SC
    injection Scapho the recommended dose with
    loading dose is administrated 150 mg SC at weeks
    0, 1, 2, 3, and 4 and q4wk thereafter 

12
PRECAUTIONS
  • When using Scapho 150mg injection will
    increased risk of infections use with caution in
    patients with chronic infection or a history of
    recurrent infection  Do not take vaccination of
    Secukinumab recipients with live virus vaccines
    because of probability of transmission of
    infection by vaccine  When using scapho
    150mg medication then Anaphylaxis and cases of
    urticaria resulted if this appears,
    discontinue scapho 150mg injection immediately
    and start anaphylaxis treatment  The treatment
    with Secukinumab should not be given to patients
    with active tuberculosis infection

13
SIDE EFFECTS
  • Swelling under your skin Sores on your
    genital or anal areas Painful skin sores
    infections  Nasopharyngitis  Diarrhea  URT
    infection  Rhinitis  Oral herpes 
    Pharyngitis  Urticaria  Rhinorrhoea

14
DRUG INTERACTION
  • CYP450 substrates co administration with scapho
    150mg injection may altered by increased levels
    of certain cytokinesLive vaccinations co
    administration with scapho 150mg should be avoided

15
CONTRAINDICATION
  • Patients having Serious hypersensitivity
    reactions to the active substance or to any of
    the excipients

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PREGNANCY
  • Pregnancy category is BUse the scapho 150mg
    injection with caution during pregnancy

17
LACTATION
  • Excretion into human milk is unknown. Use with
    caution while administrating scapho to a nursing
    woman

18
STORAGE
  • Store the drug at 20C 80CStore in original
    carton and protect from light until the time of
    use

19
MISSED DOSE
  • If failed to take a dose, patients should consult
    with medical practitioner and follow the
    instructions given by them.Or swap the missed
    dose and continue the regular dosing schedule.

20
CONTACT US 
  • EMAIL ID millionhealthpharmaceuticals_at_gmail.com
  • PHONE NO
  • 91-9940472902
  • WEBSITE URL https//millionpharma.com/scapho-150mg
    .php
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