Rituxirel 100mg injection

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RITUXIREL 100MG

• MILLION PHARMACEUTICALS

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DESCRIPTION

• Rituxirel 100mg is an anticancer medicine which
  prevents the growth and spread of cancer cells in
  the body. 
• Rituxirel 100mg injection also indicated for the
  treatment of Non- Hodgkins lymphoma or chronic
  lymphocytic and with combination with another
  anticancer drugs like methotrexate is used for
  rheumatoid arthritis symptoms in adult treatment.

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INDICATION

• Rituxirel 100mg injection and hyaluronidase human
  injection are given alone or combination with
  other drugs to treat certain types of
  non-Hodgkin's lymphoma and chronic lymphocytic
  leukemia (cancer start in WBC).
• Rituxirel 100mg injection is also used with
  methotrexate (Otrexup, Rasuvo, Xatmep, others)
  for the treatment rheumatoid arthritis symptoms
  in adults that have been already treated with
  some type of regimen known as tumor necrosis
  factor (TNF) inhibitor.

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MECHANISM OF ACTION

• Rituxirel 100mg injection is a type of class
  called as monoclonal antibody and which is a new
  type of "targeted" cancer treatment and an
  integral part of the body's immune system.
  Naturally the body build antibodies in along with
  to an antigen which has entered the body and
  attach to the antigen for destruction by the
  immune system.
• Rituxirel 100mg works by linking to the CD20
  antigen on normal and malignant B-cells. Hence
  the body's essential immune security is initiated
  to attack and kill the marked B-cells.

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PRODUCT DETAILS

• Brand Rituxirel
• Ingredients Rituximab
• Strength 100mg
• Manufactured Reliance Life sciences
• Package 100mg in a 1vial

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PHARMACOKINETICS

• ABSORPTION
• Not available
•  DISTRIBUTION
• volume of distribution is 3.1 L
•  METABOLISM
• Rituxirel 100mg metabolized by human antimurine
  antibody production.
•  EXCRETION
• Not available
• The half-life of NHL is 22 days and for RA is
  18.0 days,GPA and microscopic polyangiitis is 23
  day

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DOSAGE MANAGEMENT 

• Rituxirel 100mg injection is recommended to
  administer only through intravenous infusion not
  by IV push or bolus.
• ADMINISTRTION 
• Take an Rituxirel 100mg amount and diluted
  to final concentration of 1 mg/ml up to 4 mg/ml
  as infusion (containing either 0.9 Nacl or 5
  dextrose in water). Invert gently the bag and mix
  the solution. Dispose unused drug left in vial.

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PRECAUTIONS

• Allergic condition against Rituxirel 100mg
  injection or any other medication informs your
  doctor.
• Concerning your history of drug used which
  include in prescription, non-prescription,
  vitamins supplements, nutritional products just
  inform the doctor.
• While using Rituxirel 100mg do not take any
  vaccination or immunization without taking advice
  from doctors.

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SIDE EFFECTS

• Common effects
• fever and chills (flu like symptoms)
• Less common side effects
• Weakness nausea headache cough dyspnea
  pharyngitis

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DRUG INTERACTION

• Rituxirel 100mg drug interaction has limited data
  is available at present.
• Combination with fludarabine or cyclophosphamide
  has no effects in pharmacokinetics in CLL
  patients.
• Combination with methotrexate had no effects in
  pharmacokinetics.

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CONTRAINDICATIONS

• Hypersensitivity or murine proteins. Active
  severe infections in rheumatoid arthritis
  Uncontrolled cardiac disease.

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PREGNANCY

• Category C animal studies reproduction shown an
  adverse effect on the fetus. The drug has no
  enough and well controlled studies in humans,
  using in pregnant women benefits by warrant use
  of the drug.

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LACTATION

• Rituxirel 100mg injection excreted into human
  milk is unknown. Due to the drug belongs to large
  protein molecule, no information is available.
  Women should not breast feed during Rituxirel
  100mg treatment and 12 months following last
  dose.

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STORAGE

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• Store at 20C 30C
• Use the drug before expiry date
• Protected from direct sunlight
• Do not freeze or shake.
• Keep away from the childrens
• Discard the unused drug by asking the advice
  from doctor or pharmacist.

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MISSED DOSE

• If a dose missed to take at the time then have it
  suddenly before next dose timing, if time reach
  for next dose, then skip missed dose and continue
  and continue the regular schedule. Do not have 2
  doses at a same time.

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OVERDOSAGE

• If the patients had high dose of Rituxirel 100mg
  injection then seek immediately to the emergency
  department or poison control help line. Please
  consult the doctor for further clarification.

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CONTACT US

• CONTACT US
• EMAIL ID millionhealthpharmaceuticals_at_gmail.com 
• PHONE NO
• 91-9940472902
• WEBSITE URL
•  https//millionpharma.com/rituxirel-100mg.ph
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