Decursin

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Decursin - CAS 5928-25-6
Decursin is a coumarin from The roots of
Peucedanum ostruthium. Coumarins, such as
decursinol and decursin, are known to be the
major compounds of A. gigas. Angelica gigas roots
have been widely used traditionally in Korean
herbal medicine not only for the treatment of
anaemia, but also as a sedative, an anodyne and a
tonic. Studies have shown that decursin inhibits
VEGF-mediated inner BRB breakdown through
suppression of VEGFR-2 signaling pathway. And
decursin is able to attenuate kainic acid-induced
seizures and could have potential as an
antiepileptic drug.