Antibody-drug Conjugates - PowerPoint PPT Presentation

View by Category
About This Presentation
Title:

Antibody-drug Conjugates

Description:

Antibody drug conjugates or ADCs are important and highly effective biological drugs that are designed to treat targeted therapies for cancer patients. Unlike chemotherapy, the ADC is designed to target and kill only cancer cells and maintain healthy cells. ADC is a compound molecule consisting of an antibody that is linked to a bioactive cytotoxicity (anti-cancer agent) payload or drug. – PowerPoint PPT presentation

Number of Views:121

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: Antibody-drug Conjugates


1
Antibody-drug Conjugates
https//www.creative-biolabs.com/adc
2
WHAT IS AN ADC
Antibody drug conjugates or ADCs are important
and highly effective biological drugs that are
designed to treat targeted therapies for cancer
patients. Unlike chemotherapy, the ADC is
designed to target and kill only cancer cells and
maintain healthy cells. ADC is a compound
molecule consisting of an antibody that is linked
to a bioactive cytotoxicity (anti-cancer agent)
payload or drug.
Antibody-drug conjugates (ADCs) are currently a
major research field, mainly focused on oncology,
but in other areas such as infectious diseases
are also limited. The success of this targeted
drug delivery depends on many factors,one of
which is the performance of the linker to release
the active drug moiety under appropriate
conditions.
1
of
6
3
WE OFFER THE
BEST ADC SERVICES
Designing of an ADC is an elaborate process that
involves careful planning, meticulous execution,
and intensive trouble-shooting. An effective
combination of the most suitable components will
greatly increase the chance for a successful ADC.
Lorem Ipsum is simply dummy text of the printing
and typesetting. Lorem Ipsum has been the
industry's standard dummy.
Lorem Ipsum is simply dummy text of the printing
and typesetting. Lorem Ipsum has been the
industry's standard dummy.
2
of
6
4
ADC Manufacturing
ADC manufacturing requires proper facilities that
strictly follow the criteria and guidelines of
cGMP-standard bio-macromolecule production.
Whats more, these facilities are extremely
stringent about aseptic production and they need
to be operated under an occupational exposure
limit (OEL) below 50 ng/m3. With over a decade of
dedicated work, Creative Biolabs and our
collaborators have established manufacturing
platforms and pipelines fully designated for
large scale recombinant protein, therapeutic
antibody, and ADC manufacturing.
3
of
6
5
ADC Assessment
The ultimate goal for an ADC development project
is to deploy the resulted ADC into in vivo
systems, both in model animals and eventually
human patients, to cure cancer and other diseases
utilizing its payload efficacy. However, prior to
in vivo deployment, information regarding basic
biochemical characteristics and in vitro efficacy
must be acquired for a proper evaluation of the
ADC to determine the proceedings and directions
of the project. Creative Biolabs offers a
comprehensive set of ADC in vitro analysis
services to assist our clients determine the
biochemistry and in vitro efficacy of an ADC and
provide a guideline for project progression.
4
of
6
6
GET IN TOUCH
CONTACT US
Creative Biolabs
Established in 2004, Creative Biolabs is highly
specialized in advanced antibody biochemistry and
engineering. With more than a decade of
exploration and expansion, our current research
and service capacity covers the entire new drug
discovery and development pipeline, ranging from
early discovery, preclinical evaluations, cGMP
manufacturing, to clinical trails.
45-1 Ramsey Road, Shirley, NY 11967, USA Tel
1-631-619-7922 Fax 1-631-207-8356 Email
marketing_at_creative-biolabs.com
7
THANK YOU
6
of
6
About PowerShow.com