Formulation Research and Development Services

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What Is Pharmaceutical Formulation?
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Pharmaceutical formulation is the process of
combining different chemical substances with the
active drug to form the final medicinal product
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It is obtained after in-depth study of physical,
chemical, and mechanical properties of the drug
substance
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What is the objective of drug formulation?

• To produce a final medicinal product that is
  stable and acceptable to the patient

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Factors considered during pharmaceutical
formulations

• Physical, chemical, and mechanical properties of
  drug substance
• Polymorphism, solubility, pH, and particle size
  of drug
• Inactive ingredients or excipients to be added
• Effectiveness of the drug in phase I clinical
  trials
• Results of drug stability studies

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These factors are known through preformulation
studies
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Types of formulations

• Enteral formulations
• Parenteral formulations
• Topical formulations

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Enteral Formulations

• Available as capsules or tablets
• Used for oral administration of the drug
• Can provide rapid effect or sustained release
  from the digestive tract

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Parenteral Formulations

• Available in liquid or lyophilized form
• Used for intravenous, intra-articular,
• intramuscular, and subcutaneous
  administration. 
• Liquid form is preserved in ampoules, IV bags,
• vials, and prefilled syringes in
  refrigerators
• Lyophilized form is kept in dual chamber
  syringes,
• cartridges, and vials in refrigerators

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Topical Formulations

• Available as creams, ointments, powders or
  inhaling formulas
• Used for skin application or nasal administration

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Effects of containers on formulations

• After the drug is formulated, it is stored in
  containers of plastic, glass, and metal
• The effect of this storage in closed containers
  is observed for extended period
• Any unwanted reaction between the formulation and
  container is noted

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To know whether to formulate a drug as enteral,
parenteral or topical formulation
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You need a formulation scientist!
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What does a formulation scientist do?

• Helps you in pharmaceutical pre-formulation
  studies
• Analyzes the results of pre-formulation studies
• Conducts pharmaceutical drug or formulation
  development services
• Evaluates the finished medicinal product

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To Know more

• Email ID project_at_cognibrain.com
• Phone [phone]
• Visit us https//www.cognibrain.com
• Connect with us