icsi treatment, iui treatment, ivf treatment

1
Icsi Treatment For Infertility

• Intracytoplasmic sperm injection, popularly
  known as ICSI is a treatment where
• eggs are fertilized in an IVF lab after they
  have been aspirated from the female.
• The procedure requires injecting a single
  healthy sperm into the cytoplasm.
• IVF treatment that uses the standard
  insemination technique requires approximately
• 150,000 sperm for each egg, and on the other
  hand intracytoplasmic sperm injection
• requires just one good quality sperm per
  egg. The main use of ICSI treatment is for
• male infertility cases.

2
Icsi Treatment For Infertility

• IVF with ICSI requires using specialized
  micromanipulation tools and inverted
• microscopes that help embryologists choose
  and select individual sperm in a
• specially designed ICSI needle. This needle
  is then passed through the outer shell of
• the egg in order to inject the sperm into the
  inner part of the egg. This results in
• normal fertilization in about 75 to 85 of
  eggs that have been injected with sperm.
• However, note that a woman first must be
  stimulated with medications and have an
• egg retrieval procedure so that several eggs
  can be obtained for in vitro fertilization
• and ICSI.

3
Icsi Treatment For Infertility

• Most clinics use ICSI treatment only for severe
  male factor infertility. However, it
• can be used in any case, with either gender.
• People who go for ICSI treatment are mostly
  those who suffer from severe male
• factor infertility but do not want donor
  sperm. Also, couples with infertility due to
• sperm concentrations of less than 15-20
  million per milliliter or Low sperm motility
• i.e. less than 35 often go for ICSI
  treatment. Sometimes it is also used for couples
• that have a low yield of eggs at egg
  retrieval.

4
Icsi Treatment For Infertility

• The ICSI procedure includes holding mature egg
  with a special holding pipette.
• A very delicate, sharp and hollow needle is
  used to immobilize and pick up a single
• sperm.
• Once the sperm has been picked, the needle is
  then carefully inserted through the
• shell of the egg and in to the center of the
  egg. This way the sperm is then injected
• there into the cytoplasm. The eggs are
  analyzed the next morning for evidence of
• normal fertilization.

5
Icsi Treatment For Infertility

• For most IVF programs, the fertilization rate is
  of about 70-80 percent. This is
• however, different from pregnancy success
  rates which are shown to be higher for
• IVF with ICSI than IVF without ICSI.
• Success rates of IVF with ICSI vary according to
  the specifications of an individual
• case, the ICSI technique used, the skill of
  the person performing the procedure, the
• overall quality of the laboratory, the
  quality of the eggs, as well as the embryo
• transfer skills of the infertility
  specialist physician.

6
Icsi Treatment For Infertility

• Sometimes IVF with ICSI is done for low ovarian
  reserve situations in other words
• when there are either a low number of eggs or
  the quality of eggs is low (or both).
• In these cases, ICSI fertilization and pregnancy
  success rates tend to be lower than
• usual. This is because the main determinant
  of IVF success is the quality of the
• embryos which are further determined by the
  quality of eggs. In some cases, before
• the transfer is done, assisted hatching is
  also done on the embryos. This is done so
• as to maximize the success rate for the
  pregnancy.