Advancing Oklahomas Knowledge Economy for the Next 100 Years

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Advancing Oklahomas Knowledge Economy for the
Next 100 Years
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OCAST ROI
1987 FY2008 165.4M 3.05B
(State Funding) (Private
Federal) ROI
18.47
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HEALTH RESEARCH

• On average 25 of Health projects are funded
• Approximately 100-150 applications are submitted
  each competition
• Approximately 2 million is allocated for FY09
  competition

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Program Purpose

• Provides seed funding to superior research
  projects conducted by Oklahoma-based
  investigators for the multiple purposes of
• Enhancing the competitiveness of Oklahoma health
  researchers for national research funds,
• Recruiting and retaining outstanding health
  research scientists for the State,
• Improving health care for Oklahoma citizens and
• Strengthening the State's health care industry.

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Program Description

• OCAST awards competitive health research funds,
  through
• Professional service contracts,
• Public and private colleges and universities in
  Oklahoma,
• Nonprofit health research organizations in the
  State and
• Private enterprises of special importance to the
  Oklahoma economy.

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Program Description

• Research funded under this program investigates
• Causes
• Diagnosis
• Treatment and prevention of human diseases and
  disabilities
• Facilitates the development of health care
  products and services.

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Award Types

• HR Scientist Recruitment and Retention
• 10,000 minimum budget for each year
• 100,000 each year up to three years
• Regular Oklahoma Health Research
• 10,000 minimum budget for each year
• 45,000 maximum each year up to three years

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Award Types

• Regular New Scientist Health Research Awards
• Funding awards are made on a year-by-year basis.
• Neither approval of a multiple-year award nor
  funding of any year of a contract shall
  automatically lead to funding in subsequent
  years.
• For each year originally awarded, funding shall
  be dependent on a satisfactory annual performance
  evaluation and the availability of funds.

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ORGANIZATION ELIGIBILITY

• Oklahoma public or private colleges and
  universities
• Oklahoma non-profit research organizations
• Oklahoma enterprises of special importance to the
  Oklahoma economy.
• Enterprise defined as a firm with its principal
  place of business in Oklahoma.
• .

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APPLICANT ELIGIBILITY

• Regular Oklahoma Health Research
• Is employed by, or affiliated with, an eligible
  applicant organization
• Holds at least the rank of assistant professor if
  at a college or university, or
• Is equivalent in education and experience, as
  certified by the Chief Executive Officer of the
  applicant organization.

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APPLICANT ELIGIBILITY

• HR Scientist Recruitment and Retention
• These awards support the research projects of
  health research scientists who have previously
  not held a tenure track/or equivalent appointment
  at an Oklahoma institution
• is employed by, or affiliated with, an eligible
  applicant organization
• holds at least the rank of assistant professor if
  at a college or university, or its equivalent in
  education and experience, as certified by the
  Chief Executive Officer of the applicant
  organization and
• submits an application within four years of
  accepting employment, or becoming affiliated
  with, the applicant organization.
• Eligibility for the New Scientist Recruitment and
  Retention Program requires that a researcher must
  have not held a tenure track or equivalent
  appointment at an Oklahoma institution as a
  researcher before February 18, 2005.
• .

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APPLICANT ELIGIBILITY

• HR Scientist Recruitment and Retention
• All applicants to the Health Research Scientist
  Recruitment program MUST ALSO MAKE APPLICATION TO
  THE Regular Health Research Program.
• Do not submit two separate applications but
  include a research plan and budget forms for the
  Regular Health Research project in Appendix II in
  the Health Research Scientist Recruitment and
  Recruitment application.
• .

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APPLICANT ELIGIBILITY

• HR Scientist Recruitment and Retention
• All applicants must meet all requirements for the
  Regular Research Program.
• ANY HEALTH RESEARCH SCIENTIST RECRUITMENT AND
  RETENTION APPLICATION WITHOUT A RESEARCH PLAN AND
  BUDGET FORMS FOR THE REGULAR HEALTH RESEARCH
  PROJECT WILL BE RETURNED WITHOUT REVIEW FOR
  EITHER PROGRAM.
• .

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PREVIOUS RECIPIENT ELIGIBILITY

• OCAST requires previous recipients of Oklahoma
  Health Research contracts to demonstrate evidence
  of submission to a national funding organization
  prior to submission of a new application for
  funding.
• OCAST informs reviewers regarding satisfactory or
  unsatisfactory performance on previous OCAST
  contracts.
• .

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PREVIOUS RECIPIENT ELIGIBILITY

• An individual PI may hold only one Oklahoma
  Health Research Contract at a time
• A currently funded PI may compete with a new
  project, and, if successful, decline the current
  award to accept the new award.
• A currently funded PI may also apply if the
  current project funding ends prior to the
  beginning of funding of a new FY09 award.
• .

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CHANGE OF PRINCIPAL INVESTIGATOR (P.I.)

• If the PI of a proposed project becomes unable to
  perform the proposed research between submission
  of the application and the initial contract
  period, OCAST will not allow a change in PI.
• Consequently, if the original PI ceases to head
  the project between submission and review, the
  project will not be eligible for review.
• If the original PI is lost to the project prior
  to award, the project will not be considered for
  award.
• When a PI on a proposed project becomes unable to
  perform, the applicant organization(s) must
  inform OCAST within ten (10) days. If funds have
  been awarded, monies will revert to the Oklahoma
  Health Research fund.

• .

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DELINQUENT REPORTS

• Any PI, who has a delinquent progress report or
  has not responded to other OCAST requests for
  information, impact survey data, or special
  reports on a previously funded OCAST project,
  will not be eligible to submit an application for
  new project funding.
• Any PI, who has a delinquent progress report at
  the time of review, will not be eligible for
  review.
• Any PI with a delinquent progress report at the
  time of award will not receive a contract until
  the progress report has been submitted. In the
  latter case, if the delinquent report has not
  been submitted within sixty (60) days of the
  award date, OCAST will nullify the award and
  return the monies to the Oklahoma Health Research
  Fund.

• .

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Standards Requirements
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Solicitation Forms
Statement of Intent Application Editable forms
can be found online at www.ocast.state.ok.us
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SUBMISSION REQUIREMENTS

• Statement of Intent
• Deadline
• 500 P.M., February 4, 2009
• Delivery Method
• By mail or fax to [phone]
• Intents will NOT be accepted by email

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SUBMISSION REQUIREMENTS

• Applications
• Deadline
• 500 P.M., February 18, 2009
• Delivery Method
• by mail or hand delivered only
• No email or faxed applications

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NO EXCEPTIONS
STATEMENT OF INTENTS OR APPLICATIONS WILL
NOT BE ACCEPTED AFTER THE DEADLINES
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Required Materials
Each Health Research application must include the
following materials
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Required Materials

• 8 ½ x 11-inch white paper
• Not less than 0.5-inch margins
• Single to 1.5 spacing
• Font size not smaller than 10-pt
• Fonts must be Arial, Helvetica, Platino, Computer
  Modern, or Georgia
• Use the presentation order and headings as shown

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Required Materials

• Total section text page length includes
• Text
• Inserted graphs
• Charts
• Figures
• If not applicable, acknowledge by number the
  number and title by
• Not Applicable

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Required Materials

• Do not use
• Binders
• Notebooks
• Rubber bands
• Regular paper clips
• OCAST recommends colored sheets to set-off major
  sections of the proposal
• Do NOT type text on colored sheets.

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ADDITIONAL REQUIREMENTS

• Refer to the solicitation for the following
• IRB
• Biographical information
• Letters of recommendation
• OCAST previous and other support
• Facilities, instrumentation and resources

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RESUBMISSIONS

• A resubmission is a new proposal, which includes
  the information below
• A current Statement of Intent is required
• Indicate it is a resubmission in Item 4
• Prepare an Appendix III that includes
• a letter responding to the reviewers comments
  from the previous review and noting all changes
  in the research plan,
• a copy of the previously submitted application
  and
• all reviews of that application.

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RELEASE OF INFORMATION
OCAST is subject to the Open Meetings Act and the
Open Records Act. Statement of Intent,
application abstracts and executive summaries
from progress reports are consider public
information. HOWEVER marketing plans, financial
statements, trade secrets, research concepts,
methods or products, or any other proprietary
information are exempt by statute.
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Review Process Evaluation Criteria
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EVALUATION CRITERIA (Compare to NIH)

• In general, in addition to evaluating the
  appropriateness of the budget, peer reviewers
  evaluate applications for scientific merit
  according to the following criteria
• Significance
• Approach
• Innovation
• Investigators
• Environment
• and Overall Evaluation

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EVALUATION CRITERIA (Compare to NIH)
Significance Does this study address an
important problem? If the aims of the
application are achieved, how will scientific
knowledge or clinical practice be advanced?
What will be the effect of these studies on the
concepts, methods, technologies, treatments,
services, or preventative interventions that
drive this field?
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EVALUATION CRITERIA (Compare to NIH)
Approach Are the conceptual or clinical
framework, design, methods, and analyses
adequately developed, well integrated, well
reasoned, and appropriate to the aims of the
project? Does the applicant acknowledge
potential problem areas and consider alternative
tactics?
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EVALUATION CRITERIA (Compare to NIH)
Innovation Is the project original and
innovative? For example Does the project
challenge existing paradigms or clinical
practice address an innovative hypothesis or
critical barrier to progress in the field?
Does the project develop or employ novel
concepts, approaches, methodologies, tools, or
technologies for this area?
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EVALUATION CRITERIA (Compare to NIH)
Investigators Are the investigators
appropriately trained and well suited to carry
out this work? Is the work proposed appropriate
to the experience level of the principal
investigator and other researchers? Does the
investigative team bring complementary and
integrated expertise to the project (if
applicable)?
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EVALUATION CRITERIA (Compare to NIH)
Environment Does the scientific environment in
which the work will be done contribute to the
probability of success? Do the proposed studies
benefit from unique features of the scientific
environment, or subject populations, or employ
useful collaborative arrangements? Is there
evidence of institutional support?
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EVALUATION CRITERIA (Compare to NIH)
OVERALL EVALUATION In one paragraph, briefly
summarize the most important points of the
Critique, addressing the strengths and weaknesses
of the application in terms of the five review
criteria. Recommend a score reflecting the
overall impact of the project on the field,
weighing the review criteria, as you feel
appropriate for each application. An
application does not need to be strong in all
categories to be judged likely to have a major
scientific impact and, thus, deserve a high merit
rating. For example, an investigator may
propose to carry out important work that by its
nature is not innovative, but is essential to
move a field forward.
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EVALUATION CRITERIA (Compare to NIH)
Modifications for New Investigators (New ?
newly independent, asst. prof./member) IMPLEMENTAT
ION When reviewing these applications, reviewers
should keep in mind the experience of and the
resources available to the new investigator. When
considering an application from a new
investigator the five new review criteria must be
evaluated in a manner appropriate to the
expectations for and problems likely to be faced
by a new investigator. Specifically, when
considering Approach more emphasis should be
placed on demonstrating that the
techniques/approaches are feasible than on
preliminary results Investigator more emphasis
should be placed on their training and their
research potential than on their track record and
number of publications. Environment there
should be some evidence of institutional
commitment in terms of space and time to perform
the research.
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Solicitation Forms
Application Budgets
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Indirect Costs

• Health Research DOES NOT allow Indirect Costs
• Examples of Indirect Costs
• Building equipment depreciation, interest,
  operations and maintenance, overhead,
  administrative support, library, tuition and fees

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Direct Costs

• The Health Research program allows only research
  direct costs expenses.
• Examples of allowed direct costs
• Research related travel, supplies, equipment,
  patient care, alterations, rent, phone, and
  utilities
• Examples of non-allowed direct costs
• Advertising, public relations, food, tuition and
  fees, housing cost, automobiles, personal
  computers, lobbying costs, selling and marketing
  costs, first class air travel, patent and
  licensing fees

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Research Plan
Maximum 15 pages!
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Research Plan

• Organize sections A - D of the Research Plan to
  answer these questions
• What do you intend to do?
• Why is the work important?
• What has already been done?
• How are you going to do the work?
• The Research Plan should be prepared in the
  following format

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Research Plan

• Specific Aims
• List the broad, long-term objectives and the goal
  of the specific research proposed .
• e.g., to test a stated hypothesis, create a novel
  design, solve a specific problem, challenge an
  existing paradigm or clinical practice, address a
  critical barrier to progress in the field, or
  develop a new technology.

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Research Plan

• B. Background and Significance
• Briefly sketch the background of the proposed
  project, critically evaluate existing knowledge
  and specifically identify the gaps that the
  project is intended to fill.
• State concisely the importance of the research
  described in this application by relating the
  specific aims to longer-term objectives.
• If the aims of the application are achieved,
  state how scientific knowledge or clinical
  practice will be advanced.
• What is the innovation?
• Describe the effect of these studies on the
  concepts, methods, technologies, treatments,
  services or preventative interventions that drive
  this field.

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Research Plan
C. Preliminary Studies Provide an account of
the PI's progress, which led to formulating the
proposed project, as well as any other
information that will assist the reviewers in
assessing the competence of the PI for performing
the project.
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Research Plan

• D. Research Design and Methods
• Discuss in detail the research design and the
  clinical framework, procedures, and analyses to
  be used to accomplish the specific aims of the
  project.
• Describe the protocols to be used.
• Provide a tentative sequence or timetable for the
  investigation. Include the means by which the
  data will be analyzed and interpreted.
• Discuss any new methodology and its advantage
  over existing methodologies.
• Discuss the potential difficulties and
  limitations of the proposed procedures and the
  alternative approaches to achieve the aims.
• Point out any procedures, situations or materials
  that may be hazardous to personnel and the
  precautions that will be exercised.

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Literature Cited

• Do not scatter complete literature citations
  throughout the text.
• Reviewers find the inclusion of titles to be very
  helpful.
• Number the references in order of appearance, and
  provide the complete citations, which correspond
  to the numbers, in a list at the end of the
  Research Plan.
• Each citation must include the names of all the
  authors, the name of the book or journal, volume
  number, page numbers and year of publication.
  Although no page limitation is specified for this
  part of the application, make every attempt to be
  judicious in compiling a relevant and current
  bibliography. It need not be exhaustive.
• For references available (also) on the web add
  the address and the date you accessed the site in
  (parentheses) at the end of the source.

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Appendix II

• Required Attachment For All Health Research
  Scientist Recruitment and Retention Applications.
• All applicants to the Health Research Scientist
  Recruitment and Retention program will also be
  considered for funding under the Regular Health
  Research Program. In such cases do not submit two
  separate applications.
• For a researcher making application under the
  Health Research Scientist Recruitment and
  Retention Program, the investigator must include
  a research plan and budget forms for the Regular
  Health Research project as a separate appendix
  (identified as Appendix II) in their Health
  Research Scientist Recruitment and Retention
  application. Such applicants must meet all
  requirements for the Regular Research Program.
• ANY HEALTH RESEARCH SCIENTIST RECRUITMENT AND
  RETENTION APPLICATION WITHOUT A RESEARCH PLAN AND
  BUDGET FORMS FOR THE REGULAR HEALTH RESEARCH
  PROJECT WILL BE RETURNED WITHOUT REVIEW FOR
  EITHER PROGRAM.

Advancing Oklahomas Knowledge Economy for the
Next 100 Years