Myhep Dvir [ Daclatasvir + Sofosbuvir ] Mylan Tablets Uses, Dose, MRP Price india

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MYHEP DVIR
myhep dvir,myhep dvir tablet
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DESCRIPTION

• Drug profile
• Myhep dvir tablet, a combination of two most
  effective anti-viral agents called as Sofosbuvir
  Daclatasvir. This tablet is most effective
  against serious condition like hepatitis C viral
  infection induced by genotype I or III.
• Myhep dvir tablet is the merger of two non
  structural proteins like NS5A NS5B inhibitors.

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Prescribing information

• Myhep dvir tablet are utilized to treat the
  propelled hepatitis C viral diseases related with
  genotypes I or III.
• For the most part Daclatasvir is utilized as a
  part of mix with sofosbuvir for better against
  viral action.

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Mechanism

• After oral confirmation of Myhep dvir tablets, it
  might experience some structure for showing the
  counter pervasive action.
• Myhep dvir Sofosbuvir and Daclatasvir

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Dosage regimens

• On the basis of body weight of the patients the
  dose of ribavirin should be calculated.
• An starting dose of ribavirin is 600mg as once
  daily, followed by increasing the dose to 1000mg.
• ü lt 75kg of body weight, ribavirin dose is 1000mg
• ü 75kg of body weight, ribavirin dose is 1200mg

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Decompensated cirrhosis

• The recommended dose of Myhep dvir tablet is one
  tablet should be combined with weight based
  ribavirin

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Drug caused side effects

• Serious bradycardia during combination with
  amiodarone
• HBV reactivation
• Fatigue
• Headache
• Insomnia
• Nausea

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myhep dvir tablet(Asthenia)

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Drug- drug interaction

• Interaction with CYP3A inducers causes absence of
  action because of diminished concentration of
  Daclatasvir.
• Myhep dvir tablet simultaneously utilize with
  CYP3A intense inhibitors, prompts raise the
  plasma concentration of Daclatasvir.
• Interaction with warfarin prompts deliver changes
  in INR esteems and prothrombin time causes
  draining clutters.

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Safety measures

• HBV reoccurrence
• This may occurs in HCV/HBV co contaminated
  patients, who are experienced HCV against viral
  treatment yet not get the HBV unfriendly to viral
  treatment.
• Before occasion of HBV defilement
• Patients must be inside and out checked whether
  suspected with HBV pollution or not.

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Storage and handling

• Myhep dvir tablet container should be stored by
  keeping at temperature of below 30oC
• This container should be free from moisture,
  heat light.
• Missed dose
• Myhep dvir tablet is a single dose therapy, if
  patient does not take the dose of Myhep dvir
  tablet must be consult with physician and follow
  the advice.
• Otherwise the missed dose should be avoided and
  continue the regular schedule.

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Over dosage

• The maximum dose of Sofosbuvir is 1200mg, in case
  of over dosage condition
• Patients may provide with supportive measures
• Alternative medicines should be recommended
• Sofosbuvir over load is eliminated from the body
  by undergoing hemodialysis 4 hours of process
  should remove nearly 18 of sofosbuvir content
  from the body

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