Buy Erlonat/Erlotinib 150mg tablets with price | Myapplepharma

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Erlonat 150mg tablet   Erlotinib 150mg tablets

• Myapplepharma

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Erlonat 150mg tablet (Erlotinib)

• Erlonat tablets consist of active ingredients
  known as Erlotinib (Generic Tarceva), that is
  considered as quinazoline derivative and
  anti-cancer agents that responses as a protein
  kinase prohibitors for EGFR related to tyrosine
  kinase.
•  Erlonat is majorly used in the treatment of
  non-small cell lung cancer and pancreatic
  carcinoma and also involved to treat various
  cancers. 
• Erlonat 150mg is especially aimed the epidermal
  growth factor receptor tyrosine kinase.

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USES OF Erlonat

• Erlonat is indicated as continuance therapy, in
  patients with long lasting or metastasis non
  small cell lung carcinoma, whose disease has not
  get advance after four cycles with platinum based
  first line therapy
• Erlonat is used in this condition only after the
  failure of one prior chemotherapy regimen. 
• Erlonat 150mg with platinum based compounds like
  Carboplatin, gemcitabine or cisplatin. 

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Erlonat WORKS

• Erlonat has pharmacological effects like
  anti-neoplastic activity, which exhibits its
  action by inhibiting the intracellular
  phosphorylation of tyrosine kinase related with
  epidermal growth factor receptor.
• This EGFR is present on the surface of the tumor
  cells.
• Thus results as inhibition causes interfere with
  signal transduction and lead to cell lyses.

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PHARMACOKINETICS

• The peak plasma concentration time reaches at 4
  hours after drug intake After an oral
  administration of Erlonat, causes 60 of oral
  bioavailability. Increased by meals to 100.
• Smoking should be avoided during the treatment
  with Erlonat 150mg, causes decreasing the
  exposure of Erlotinib. The apparent volume of
  distribution of Erlotinib is 232L Human protein
  binding to Erlotinib is occurs as 93. 
•  Erlotinib metabolites occurs via Feces 83
  urine 8 half life period of Erlotinib is 36.2
  hours.

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WARNING AND PRECAUTIONS

• Pulmonary toxicity Interstitial lung disease and
  other pulmonary toxicity conditions, Avoid the
  treatment with Erlonat Renal failure Frequent
  monitoring of renal function or serum
  electrolytes occurs or avoids the treatment
•  Hepatic function should be periodically
  monitored, or otherwise discontinue the therapy
  with Erlonat.

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SOME INTERACTION WITH SOME OTHER DRUGS

• Co administration of Erlonat with midazolam
  causes decreasing the AUC of CYP3A4 substrate.
  Drugs involved in alteration of pH levels causes
  variation in solubility of Erlotinib. Avoid
  concomitant use of gastric regulators
  with Erlonat.
• Erlonat concomitant with statins drugs (lipid
  lowering drug), causes increasing the
  concentration of these drugs (rosuvastatin,
  simvastatin or atorvastatin).
• CYP3A4 strong inhibitors like itraconazole, grape
  fruit juice, rotonavir, indinavir etc CYP3A4
  inducers concurrently used with Erlonat tablets
  causes decreasing the exposure of Erlotinib. 

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CONTRAINDICATION

• In Erlonat 150mg therapy, no contraindication
  occurs.
• In some patients hypersensitivity reactions
  present due to patients are contraindicated to
  the ingredients in Erlonat.
• In case of missed dose, patients must consult
  with medical oncologist and follow the regular
  dosing schedule.

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SIDE EFFECTS

• some undesirable effects like
• Paronychia, Bullous, blistering and expoliative
  skin conditions like Stevens Johnsons syndrome.
  Gastrointestinal perforation Hepatic failure
  occurs during monotherapy or combination with
  other chemotherapy agents 
• Some common side effects
• Diarrhea, Fatigue, Anorexia, Pruritus, Acne,
  Dermatitis, Dry skin, Loss of weight, Paronychia,
  Cough, Vomiting, Conjunctivitis,
  Keratoconjuctivities sicca, Abdominal pain,
  Stomatits, Infection, nausea, Bone pain,
  Alopecia, Anxiety, Neuropathy, Renal disorders,
  hepatic disorders, ocular disorders, skin, hair
  and nail disorders.

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