CaBIG: Network Centric Biomedicine

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CaBIG Network Centric Biomedicine

• Ken Buetow, Ph.D.NCI Associate Director
  Bioinformatics and Information Technology
• October 3, 2007

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Molecular Medicine as a Complex Continuum
Molecular Medicine
Imaging
Clinical Research
Pathology
Molecular Biology
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caBIG Connects the Cancer Community
Researchers, Clinicians, Patients
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caBIG Approach

• Modules that address specific needs
• Use of international data standards
• Connect through defined Electronic interfaces

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caGrid 1.1 Conceptual View
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caBIG Product Suites

• Electronic Clinical Trials Management Framework
• Life Sciences Distribution
• Security and Data Sharing

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CTMS Framework

• The CTMS Framework brings together a range of
  interoperable tools supporting the clinical
  trials enterprise.
• Functions include
• Patient Study Calendar (PSC)
• Participant Registry (C3PR)
• Adverse Event Reporting (caAERS)
• Clinical Source Data Integration (caXchange)
• Integration with Cancer Central Clinical Database
  (C3D), or with commercial clinical trials data
  collection tools at sites

CTMS Framework
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Life Sciences Distribution

• The Life Sciences Distribution brings together a
  range of caGrid-interfaced tools supporting
  biomedical informatics
• Functions include
• Tissue Banking (caTISSUE Suite)
• Gene Expression Database (caArray)
• Translational Medicine tools (caIntegrator)
• Biomedical Image Management (NCIA)
• Array analysis (geWorkbench)
• and the supporting caGrid infrastructure

Biomedical Informatics Bundle
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Data Sharing and Intellectual Capital

• The DSIC Bundle provides a critical range of
  processes, procedures, policies and template
  agreements that provide a framework for
  collaboration
• Bundle includes
• Master Guidance Document
• Flow document and questionnaire
• Decision tree
• Template agreements for MTA, IRB, etc.
• Security policies, procedures, and a framework
  for caGrid-wide authorization
• and a framework for participating in the DSIC
  process, refining the structure for data sharing
  throughout the program

DSIC Bundle
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caBIG Support

• Application Support
• E-mail
• Phone support
• List Servers
• caBIG boot camps
• Developers
• Application Users
• Online Interactive Training
• Down-loadable User Materials
• Training Sessions at Scientific Meetings

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caBIG Enterprise Support Activities
Knowledge Centers
Program Offices
Designated Support Contractors
Enterprise Adopter Program
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http//pid.nci.nih.gov
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http//caintegrator.nci.nih.gov/cgems
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http//caintegrator.nci.nih.gov/rembrandt
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Grid of Grids
NCI caGrid
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Join the effort!!!

• More information
• caBIG.cancer.gov
• Join caBIG effort
• caBIG.nci.nih.gov