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A Mycology Atlas

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Malassezia furfur does not grow on Sabouraud dextrose agar. Cryptococcus neoformans, skin biopsy. Note the presence of yeast cells surrounded by a clear halo. – PowerPoint PPT presentation

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Title: A Mycology Atlas


1
A Mycology Atlas
  • Prof. Khaled H. Abu-Elteen

2
Cryptococcosis, face. This patient had
cryptococcal meningitis with cutaneous lesions.
Note the unusual ulcerations. Patient was
severely immunocompromised with HIV disease.
3
Histoplasmosis, face. There are numerous
erythematous plaques on the skin of this patient
who had disseminated histoplasmosis spread from
his lungs. This individual was HIV positive.
4
Tinea barbae upper lip. This represents an
unusual presentation of a fungal infection
involving the skin. Note the scaly plaque just
underneath the nostrils and above the lip.
5
Tinea corporis, eyelid. The eyelid is an unusual
site for a fungal infection. Note the
erythematous scaly plaques.
6
Tinea capitis. Here is a severe, persistent form
of a tinea infection involving the scalp and
resulting in considerable loss of hair. The
hypopigmentation is due to the inflammation
associated with this chronic infection.
7
Candidiasis, scallp. This case represents a
subcutaneous and cutaneous form of candidiasis
with loss of hair.
8
Candidiasis, tongue (Thrush). The condition is
characterized by white thick mucoid plaques which
adhere to the tongue and mucosal surfaces, but
can be easily scraped off for examination
9
Candidiasis, tongue. This condition may be one of
the earliest signs of underlying immunodeficiency
in a patient with HIV infection. A KOH smear of
the scrapings reveals the characteristic hyphae
of the yeast organism
10
Tinea corporis, arm. This picture shows the
classic appearance of what is commonly called
"ringworm". Erythematous circinate plaques with
scaly margins are typical.
11
Tinea versicolor, neck and upper back. This
chronic infection has resulted in the loss of
pigmentation in the infected areas. Lesions
become more evident as patients go in the sun.
12
Versicolor, shoulder. There is involvement of the
supraclavicular region in this young female
patient. These lesions tend to recur periodically
once an individual has acquired this fungal
infection.
13
Tinea corporis, neck. Here one sees scaly,
slightly hyperpigmented plaques in a linear
distribution.
14
Tinea corporis, axilla. Fungal infections in the
axillary region are often scaly and itchy, and
become ulcerated due to maceration.
15
Candidiasis, thigh. Note the marked erythematous
plaques and the satellite papular lesions at the
peripheral margins of the larger infected areas
16
Candidiasis, thigh. Close-up.
17
Onychomycosis, toenails. Note the thinning and
friable nature of the nails.
18
Onychomycosis, toes with tinea pedis
19
Tinea pedis, foot. The redness and scaling
typically seen with this condition extend over
the toe web onto the toes.
20
Candidiasis, toenails. Marked thickening and
discoloration, along with deformity of the
toenail, are commonly seen in this condition.
21
Candidiasis, web of fingers. Candida infections
of the skin are often associated with cracking,
scaliness and erythema
22
Candida albicans, culture on Sabouraud dextrose
agar. Note the white color and smooth texture.
Candida albicans is the yeast most frequently
isolated from human infections.
23
Candida albicans., direct microscopic examination
of skin scrapings (KOH mount). Note the hyphae
with buds and individual yeast cells, many with
buds. The original magnification was about 400x.
(Compare with the KOH mount of the dermatophytes.)
24
Trichophyton rubrum, culture on Sabouraud
dextrose agar. Note the white, wooly texture of
this dermatophyte. It also produces a red or
red-brown pigment on the undersurface.
25
Direct microscopic examination of dermatophytes
in skin scrapings (KOH mount). Note the
thread-like filaments which break into chains of
spores (arthroconidia) in certain areas.
26
Malassezia furfur, skin scraping. This was taken
from a patient with tinea versicolor. Note the
short hyphae and clusters of thickwalled cells.
Malassezia furfur does not grow on Sabouraud
dextrose agar.
27
Cryptococcus neoformans, skin biopsy. Note the
presence of yeast cells surrounded by a clear
halo. This clear zone represents the space
occupied by the thick capsule formed by the
organism in tissue.
28
Histoplasma capsulatum, cell cytoplasm. About
eight of these tiny yeasts can be seen in the
cytoplasm.
29
Blastomyces dermatitidis, tissue. Note the round
yeasts with only a single bud.
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