Information Tools for USC Pharmacy Students

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Information Tools for USC Pharmacy Students

• Pam Corley, AHIP, MLIS
• Eileen Eandi, MLS
• Adrian Follette, MLIS
• Joseph Pozdol, MLIS
• Evans Whitaker, MD, MLIS
• Norris Medical Library
• Keck School of Medicine
• University of Southern California
• Los Angeles, CA 90089-9130

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Introductions

• Introduce personnel
• ASK QUESTIONS!
• Make this session useful to you
• Janis Brown is the liaison to Pharmacy from
  Norris Medical Library
• You may contact any of us if you have questions
• We will post this PowerPoint on the website for
  you to look at if you wish to look at it further
• (Key Resources?Student?Pharmacy?Y1.

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Handouts

• Assignment Questions
• Formatting Your Assignment
• Submission form
• Advanced Ovid Flow Sheet
• Pharmacy resources and Norris Library
• Evaluation form

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Pharmacy Y1 Assignment, due September 10, 2008

• 7 topics, we will assign one
• Search using Advanced Ovid
• Select 5 relevant articles
• Hand in
• Submission form as front page
• Printout which includes
• Search strategy
• Citation and abstract for five articles

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Outline for today

• Primary literature (another way to say MEDLINE)
• A. Practice with Advanced Ovid Search
• Norris Medical Library home page tour
• Pharmacy Resources of Note
• Predigested primary literature information
  sources (AKA Clinical Information Tools)
• Other topics as time and interest allow

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Primary Medical Literature
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MEDLINE

• MEDLINE a subset of PubMed.
• gt16 million citations in MEDLINE.
• gt18 million citations in PubMed.
• Difference due to articles not yet indexed or
  those that never will be as not biomedical
• Updated daily
• Two major ways to access
• OvidSP to which USC subscribes.
• PubMed (free, USCs version, PubMed_at_USC includes
  links to USC holdings).

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OvidSP

• Navigate to Ovid Norris homepage ? Databases tab
  ? Ovid MEDLINE.
• Sign into training account ovidsp.ovid.com.
• User sci001
• Password medical
• The training account
• Opens is Basic mode
• Has no full text links
• Opens with Search history and Limits closed
• vs. Norris Librarys version of Ovid

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OvidSP

• Many Ovid databases
• MEDLINE choices are at the top
• MEDLINE 1996-2008 and MEDLINE 1950-2008
• Ovid also contains
• EBM sources in the middle of the page.
• International Pharmaceutical Abstracts at the
  bottom.
• Set up a free personal account to save searches,
  receive automatic updates, and annotate articles.

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Ovid MEDLINE

• Advanced Ovid Search (use for assignment)
• powerful, precise search engine
• good for thorough, focused searches
• learning curve
• search methods translate to PubMed
• Ovid Basic Search
• Google-like
• natural language search engine
• use keywords, phrase, or sentence
• fast to use
• good for a few good articles

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Advanced Ovid Search

• Enter Concepts one at a time.
• MeSH (Medical Subject Headings) terms are
  preferred search terms.
• MeSH is a standardized vocabulary of the NLM used
  to index MEDLINE articles.
• With each MeSH concept decide on Explode, Focus,
  and Subheadings.
• AND, OR are used to combine concepts.
• A variety of limits may be used to narrow your
  search. HINT Place limits as the last step in
  formulating your search.

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What is Advanced Ovid good for?

• Advanced Ovid allows precise searching at the
  cost of increased time and difficulty
• Good for leaving no stone unturned, as when
  preparing for scholarly presentation.
• Limitations Advanced Ovid depends on MeSH terms.
  New drugs, procedures, devices, and concepts are
  likely not in the MeSH database (yet). Other
  strategies are needed to find articles about
  these topics.

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In-class demonstration 1

• Is Tylenol an effective treatment for migraine?

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In-class 1 Strategy

• Concept 1 migraine
• Explode
• Focus
• Subheading drug therapy
• Concept 2 Tylenol
• Explode
• Subhead therapeutic use
• Combine1 and 2
• Limits humans, English

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In-class demonstration 2

• Find studies that discuss the side effects of
  statins.

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In-class 2 Strategy

• Concept 1 statins
• Explode
• Focus
• Subhead adverse effects (toxicity, poisoning)
• Limits humans, English

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In-class demonstration 3

• Is it safe for heart patients to take Viagra?

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In-class strategy 3

• Concept 1 heart disease
• Explode
• Focus
• Concept 2 Viagra (as keyword) OR with generic
  name sildenafil (as keyword)
• Combine1 and 2
• Limits humans, English

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Questions to try on your own in-class 1

• Can secondhand smoke cause lung cancer?

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On your own strategy 1

• Concept 1 lung cancer
• Explode
• Focus
• Subheading etiology, chemically induced?
• Concept 2second hand smoke
• Subhead adverse effects
• Combine1 and 2
• Limits humans, English

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Questions to try on your own in-class 2

• Should Advil be used to treat children with
  migraines?

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On your own strategy 2

• Concept 1 Advil
• Explode
• Subhead therapeutic use (adverse effects?)
• Concept 2 migraine
• Explode
• Focus
• Subheading drug therapy
• Combine1 and 2
• Limits humans, English, children

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Questions to try on your own in-class 3

• Is Zyrtec or Claritin more effective in treating
  seasonal allergies? What about Allegra?

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On your own strategy 3

• Concept 1 Seasonal allergic rhinitis
• Explode
• Focus
• Subhead drug therapy
• Concept 2 Claritin
• Concept 3 Zyrtec
• Subheading for 2, 3 drug therapy
• Concept 4 Allegra (fexofenadine)
• Combine1 and (2 or 3 or 4)
• Also can do 1 and 2 and 3 and 4
• Limits humans, English

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Ovid Basic Search Tips

• Search engine translates your words (mapping).
• No need to separate concepts.
• You may apply limits
• Basic searches typically yield gt 500 hits.
• The good stuff in the first 20-30 hits.
• If nothing within 20-30 hits,
• reword your question or,
• use Advanced Ovid Search.

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OvidSP Take Home Messages

• Use Basic to inform Advanced.
• Minimize use of subheadings and limits.
• Rule of thumb is to focus only one concept
  (usually the disease or condition) and explode
  all concepts in a search.
• Apply limits as the last step.
• In Advanced mode always attempt to translate your
  terms into MeSH headings.

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Norris Medical LibraryAccess and Homepage Tour
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Norris Medical Library

• Use the proxy server. (You can see it at
  https//libproxy.usc.edu/login ). There is no
  need to use VPN.
• Log in with USC email information user name
  (email up to _at_) and password.
• Use Norris Library home page as your starting
  point when searching for biomedical information
  -- Bookmark it!

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The Norris HomepageHighlightsMoving from Left
to Right

• Journals
• All USC eJournals includes all electronic
  journals in the USC system
• Databases
• Ovid MEDLINE
• PubMed _at_USC dont go directly to pubmed.gov as
  lose links to USC holdings
• Key Resources for Students ? Pharmacy Portal
  to commonly used resources
• Catalogs
• HELIX -- Norris Medical and Wilson Dental
  Libraries (try goodman and gilman)
• ADVOCAT -- USC Law Library
• HOMER -- All other USC libraries
• QuickLinks -- many common resources listed in
  dropdown menu.
• HELP Email, Phone, and IM connections to
  medical librarians. We can help with devising
  searches, finding information sources,
  troubleshooting, etc. IM and phone hours are M-F
  9-5. There is one working day turnaround on email
  questions.
• SEARCH

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QuickLinks

• Clinical information tools
• UpToDate not off campus
• ACP Pier
• Essential Evidence Plus
• Pharmacy References
• Epocrates
• Lexi-Comp Online
• Databases
• Ovid MEDLINE - has much more than MEDLINE
• PubMed_at_USC - dont use pubmed.gov

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QuickLinks 2

• DocRetriever Interlibrary loan system of Norris
  Library. Set up free account, the system is
  self-serve. Charges for items from libraries
  outside USC -- 11 for book or article.
• Multi eBook Search Use to find information in
  multiple electronic sources simultaneously. Easy
  to use and searches gt700 electronic books
  simultaneously!

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Pharmacy Resources of Note
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• Access Pharmacy -- contents of 22 books
  searchable by topic or organ system, self
  assessment, a few videos, drug monographs (from
  Gold Standard), etc.
• International Pharmaceutical Abstracts in Ovid,
  produced by American Society of Health-System
  Pharmacists, covers 1970 to current
• Lexi-Comp -- has ASHF data as well
• Epocrates -- clinician-oriented drug database
• Statref A and B -- access to a variety of
  relevant books
• ChemAbstracts through SciFinder Scholar can
  search for literature, chemical structures.
  Download required
• MicroMedex multiple pharmaceutical databases

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Clinical Information Tools
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Clinical Information Tools

• UpToDate fast, easy, good quality. Is it really
  evidence-based? Or is it expert opinion? Do we
  care? QuickLinks. Great for background
  information.
• ACP Pier QuickLinks. Similar content to UTD but
  not as nice an interface.
• Essential Evidence Plus InfoRetriever until
  recently QuickLinks. Same comments as ACP Pier
• Try a search in ACP Pier, Essential Evidence, and
  Clinical Evidence. Call out if you need help or
  have questions.
• Topics (if you need them)
• Suicide risk with SSRIs in teens.
• Steroid injection for lateral epicondylitis.
• Calcium channel blockers for migraine
  prophylaxis.

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Evidence Based Practice Resources

• Clinical Evidence Search NML for clinical
  evidence
• Ovid EBM databases Access via Databases?Ovid?
  select a database. Remember Change Databases and
  Open And Re-execute to speed looking through
  Systematic Reviews, DARE, ACP Journal Club try a
  search with concepts fluoxetine, suicide,
  adolescents. (usc.edu/nml/ovid/)
• National Guidelines Clearinghouse
  (guidelines.gov) try fibromyalgia
• TRIP database (tripdatabase.com) -- try ankle
  sprain notice patient handouts and images tabs
• SUMSearch (sumsearch.edu) try irritable bowel
  syndrome

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Search Tips for Clinical Information Tools and
EBP/EBM

• Keep your searches simple.
• Be prepared to reword your searchthere is no
  mapping of terms to a standardized vocabulary in
  these resources, unlike OvidMEDLINE or PubMed.

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PubMed_at_USC
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PubMed_at_USC

• Databases tab at Norris homepage
• Insures full text links through FindIt_at_USC.
• Open PubMed_at_USC.
• I will only mention three features today.
• Single Citation Matcher.
• Find Similar.
• MyNCBI
• Search process is similar to OvidSP Advanced. Use
  MeSH terms, enter concepts separately, combine
  concepts, apply limits.
• Sign up for MyNCBI -- save searches, collections
  of articles, and have new articles resulting from
  saved searches emailed to you on a
  user-determined schedule.

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PubMed

• Single Citation Matcher any 1-2 pieces of
  information will allow you to find a citation.
  Usually will have links to USC holdings.
• Related Articles is a very effective way of
  finding closely related articles. Ovid has the
  equivalent function. It does not work as well.
• MyNCBI personalized account in which you can save
  searches and articles.

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Sign Up for MyNCBI

• Do this now!
• For those of you who have not already done so
  this is free, easy, and no associated spam.
• With MyNCBI you may save searches and article
  collections. If you so designate, your saved
  searches are rerun periodically. New articles on
  your topic are emailed or RSSd to you.

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Miscellany
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Tips

• GoogleScholar limits searches to scholarly sites
• Configure GS in Scholar Preferences so that USC
  library holdings are linked (for personal
  computer)
• GS is good for preliminary exploration of an
  unfamiliar topic. Yields good terms to use in
  more valid and authoritative search engines.
• GS will also occasionally find full text of an
  article in a journal to which USC does not
  subscribe.

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Scirus.com

• A search engine devoted to scientific websites.
  Easy to use. Higher overall quality of sites than
  GS. My opinion
• Independent product of publishing giant
  Elsevier. I have not seen evidence of bias.
• Worth a look when exploring a topic.

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Tips

• Norris as home page, use proxy server.
• Sign up for a free account with Ovid to save
  searches and annotate articles.
• Sign up for a free MyNCBI account, you can save
  PubMed searches, collect articles, and have
  alerts emailed to you about new articles from
  saved searches.
• Sign up for free eTOCS for those journals whose
  contents you want to scan regularly.
• Sign up for free Web-of-Knowledge/EndNote
  accounts. This is a nice way to store, organize,
  and use citations found in your research.
  Consider Connotea as well.
• Consider classes at your local library in PubMed,
  OvidSP, EndNote, etc.

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Summary

• We have attempted to provide
• Norris Medical Library basics.
• OvidMEDLINE update and usage information.
• Miscellaneous information GoogleScholar and
  Scirus.com.
• Some time to practice with the resources.
• Thanks for your attention!