The Pie of Schizophrenia (Theoretical)

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The Pie of Schizophrenia (Theoretical)
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Schematic of chromosome 6 giving twopotential
linkage hotspots.
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FrontiersGenetics
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Summary of Linkage Results in Schizophrenia
From Owen et al., Trends in Genetics (2005), 21,
518-525
Red lines genome-wide significanceBlue lines
significant in more than 1 sample Red arrow
possible chromosomal anomoliesYellow potential
candidate genes
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FrontiersEndophenotypes
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FrontiersGenes and Neuroimaging
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Legend for the next two figures
From Heinz et al. (2004). Nature Neuroscience, 8,
20-21.
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From Heinz et al. (2004). Nature Neuroscience, 8,
20-21.
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From Heinz et al. (2004). Nature Neuroscience, 8,
20-21.
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Legend for next Figure
From Hariri et al. (2005), Arch gen Psychiat
62146-152
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From Hariri et al. (2005), Arch gen Psychiat
62146-152
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From Hariri et al. (2005), Arch gen Psychiat
62146-152
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FrontiersGenes-environment Interaction
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From Caspi et al., Science 297-851-854
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From Foley et al., Arch gen Psychiat, 61738-744
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Depression as a function of stressful life events
and the short-longpolymorphism in the serotonin
transporter gene
From Caspi et al., Science 301, 386-389