What is Biochemistry

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What is Biochemistry?

• Describes the structure and organization of
  living matter in molecular terms.
• What are the chemical structures of components of
  living matter?
• How are these structures organized to
  supramolecular structures, cells, tissues and
  organisms?
• How do living things extract enegry from its
  surroundings to stay alive?
• How do organisms store and transmit the
  information to grow and reproduce themselves?
• What chemical changes accompany the production,
  aging and death of cells and organisms?
• How are the reactions controlled inside living
  cells?

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Areas of Biochemistry

• Structural chemistry components of living matter
  and relation to biological function to chemical
  structure
• Metabolism Totality of chemical reactions
  occurring in living matter
• Information storage and transmission Chemistry
  of processes and substances, also includes
  molecular genetics (seeks to understand molecular
  grounds of heredity and expression of genetic
  information)

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A Chemical Science Biochemistry
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Biological Molecules
Immunoglobulin, 150,000 Da
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A Biological Science Biochemistry
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Microscopy
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The matrix of life Weak interactions in an
Aqueous Environment
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Permenant and induced dipole interactions
Polar or permanent dipole, said to have permanent
dipole moment, ?
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Hydrogen bond
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Hydrogen Bonding in Water
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Amphipathic molecules
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Interaction of amphipatic molecules in water
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pH Scale
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Titration Curves of Weak Acids
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Molecules with Multiple Ionizing Groups
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Relative Concentrations of the three forms of
glycine as a function of pH
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Electrostatic Interactions Between Microions
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Dependence of Protein Solubility on pH
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The Influence of Small IonsIonic Strength
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Chapter 3The Energetics of Life
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Equilibration Across a Membrane
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