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Quantitative Traits

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Typical mendelian traits. No overlap between classes of phenotypes. Tall pea plants ... Mendelian genetics explains quantitative traits, if one assumes multiple genes ... – PowerPoint PPT presentation

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Title: Quantitative Traits


1
Quantitative Traits
  • Multigenic phenotypes
  • Chapter 8.1, 8.3, 8.5, 8.6, 8.7

2
  • Qualitative Traits
  • Typical mendelian traits
  • No overlap between classes of phenotypes
  • Tall pea plants
  • Short pea plants
  • Single genes
  • Quantitative traits
  • Blending
  • Overlap, no discreet classes
  • Height in Humans
  • Swimmng Speed
  • Multigenic interactions
  • Overlapping of Environmental and genic
    interactions

3
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4
Quantitative Traits and Mendel
  • Mendelian genetics explains quantitative traits,
    if one assumes multiple genes and some incomplete
    dominance

5
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6
Measuring Heritable Variation
  • Differences in Phenotypes in quantitative trait
  • Environment
  • Genetics
  • Heritability
  • Fraction of total phenotypic variation (VP)
    within a population that is due to genetic
    differences (VG)

7
Narrow-Sense heritability
  • Total Genetic variance is the sum of additive
    gene interaction (VA), Dominance interactions
    (VD), and other interactions
  • Narrow-sense heritability (h2) is only concerned
    with VA

8
  • h2 can be measured as slope of a line of a plot
    of offspring values vs. parental values
  • Why do we concern ourselves with h2?
  • selection

9
H2 and Selection
  • Additive gene interactions respond quickly to
    selection
  • Heritabilty studies can help you understand
    evolutionary history and response

10
What heritability cant tell you
  • Heritabilities are snap shots in time
  • Depending on environment traits can exhibit
    higher or lower values
  • Heritabilities do not predict mean values for
    phenotype between populations, nor how those
    genotypes will react in differenct environments

11
  • Achilla is a native wildflower
  • Height in Achilla is highly heritable
  • Identical clippings grown it Mather and Stanford
    experimental gardens
  • Another trait in Achilla is number of stems
  • Low Altitude plants make more stems than high
    altitude plants

12
Experiment Culture low and high altitude plants
to new altitudes
13
Bell Curve fallacy
14
Experiment to test Bell Curve Hypothesis
15
  • Heritability does not mean genetic
  • Heritability is not a permanent feature
  • Heritability only predicts what will happen to a
    population under specific conditions

16
End of Chapter problems
  • Chapt. 8 4, 5, 6, 7
  • Chapt. 7 1, 2
  • Chapt. 6 6, 7, 8, 9, 10, 11, 16
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