Olive Leaf Extract

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Olive Leaf Extract

• By
• Adirondack(M) Sdn. Bhd.

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What is Olive leaf extract

• Olive Leaf Extract is derived from the leaves of
  the olive tree.
• It contain oleuropein, an enzyme which break down
  into elenolic acid.
• Elenolic acid is found to have powerful
  antiviral, antibacterial,antifungal and
  antiparasitic effect.

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History of olive leaf extract ?

• Olive trees has always been referred to as the
  king of trees in ancient times.
• It has been written in the scriptures that God
  speaks of a tree where the fruit shall be for
  meat, and the leaf there of for medicine. That
  tree today is the olive plant.
• Thomas Jefferson call the olive tree as the
  richest gift of Heaven in view of the numerous
  inherent health qualities it could contribute to
  mankind.

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Discovery of olive leaf extract

• In 1800, Dr Etienne Pallas M.D. discovered the
  medicinal effects of olive leaves.
• He isolated a crystallisable compound and name it
  vauqueline, a bitter substance to which he used
  for fever reducing treatment.

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Discovery of olive leaf extract

• The breakthrough for the olive leaf extract came
  in 1995 when East Park Research developed a
  patented extraction process (Stereoisomer
  extraction), which extracts the therapeutic
  elements from the leaf.
• The product produced under this new patent is
  called OD-LenolateO olive leaf extract

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How does olive leaf extract works on virus ?

• Oleuropein interferes with some specific amino
  acid processes that is vital to the life cycle of
  virus.
• Oleuropein inactivate and prohibit virus from
  shedding, dubbing or assembly at the cell
  membrane.
• Stimulate host defense system by direct
  stimulation of phagocytosis

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How does olive leaf extract works on virus ?

• Oleuropein neutralize the reverse transcriptase
  and protease (ie relates to retroviral ability to
  alter the host cell RNA).
• Oleuropein penetrate infected host cells while
  inhibiting viral replication.
• Note The antiviral activity of elolenic acid is
  greatest in an alkaline environment of pH 7.5
  which is very close to our normal blood pH of
  7.35-7.45

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How does olive leaf extract works on bacteria ?

• Oleuropein slows down the growth rate and
  inhibits a number of enzymes.
• It induces damage to the bacterial cell membrane
  thus affecting its permeability and resulting in
  a leakage of cytoplasmic constituents.
• It inhibit micrococcal nuclease and lysozyme.

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How does olive leaf extract works on bacteria ?

• Oleuropein inhibits enzymes by reacting with the
  e-amino group of exposed lysine residues and the
  exposed n-terminal amino group of polypeptide
  chains.
• Irreversible inhibition of DNA polymerase II and
  inhibition of DNA polymerase III holoenzymes.
• Immune activation of host defense through direct
  stimulation of phagocytic activity.

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How does olive leaf extract works ?
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Benefits of olive leaf extract

• Helps to lower blood pressure and reduce
  cardiovascular disease.
• Helps decrease blood sugar level.
• Contain antioxidants that inhibit oxidation of
  LDP (low density lipoprotein) or so called bad
  cholesterol).
• Reduce swollen lymph nodes.
• Helps in eliminating herpes and shingles (Herpes
  zoster).

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Benefits of OLE

• Reduce uric acid, acidity and gout problem.
• Helps to reduce chronic fatigue syndrome.
• Fights against fungal infections and vaginal
  yeast infections.
• Helps in the treatment of Malaria and Dengue
  infections.
• Slows down degenerative diseases and boost immune
  system

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Are there any side effects ?

• No, because olive leaf extract is non-toxic.
• However, a die off or healing crisis may occur
  from killing too many pathogens too quickly.
• This is experienced as "flu-like" symptoms or
  allergic attacks.

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How does this happen ?

• When large quantities of microbes are killed off,
  the bodys cell membranes tend to absorb some of
  the toxic products from these dead organisms.
• This may cause an allergic response (ie pain and
  swelling of the joints, sinuses, slight pain at
  the eustachian tubes in the ears etc.)

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How to overcome the healing crisis ?

• If unfavourable reactions still continue,
  decrease the dosage by half.
• Stop consuming the olive leaf extract until
  symptoms recover.
• Drink as many as 3 to 4 glasses of water after
  each dosage.

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OLE and fungus/yeast infection.

• Olive leaf extract is antifungal and anti-yeast.
• Because antibiotics kill both the friendly and
  unfriendly organisms, they upset the delicate
  balance of our bodys natural defenses.
• The result has been a paradise for yeast and
  fungi not harmed by the antibiotics, which
  flourish without competition from other natural
  bacterial allies.

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OLE and fungi/yeast infection

• Since yeast prefers a diet high in sugars, our
  overindulgence in sweets further benefited yeast
  populations and contributed to illness and
  disease.
• Fungi and yeast species that have shown
  sensitivity to oleuropein include geotrichum
  candid urn, rhizopus sp. and rhizoctonia solani.

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OLE and heart disease

• Atherosclerotic heart disease and stroke remains
  the number one killer despite all the advances in
  medicine.
• A major risk factor for artherosclerosis is the
  elevation of serum lipids ie LDLs.
• Oxidised LDLs are taken up by the endothelial
  cells and monocytes by way of their scavenger
  receptor,

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OLE and heart disease.

• This lead to the formation of cholesterol ester
  loaded foam cells and atherosclerotic plaques.
• In the advanced stages, this can lead to the
  death of the endothelial cells (which is the cell
  at the innermost layer of the blood vessel).
• Oleuropein is a polyphenolic compound these
  naturally occurring phytochemicals are very
  potent antioxidants.
• Oleuropein has been shown to inhibit the
  oxidation of LDLs and atherogenic activity.

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OLE and hypertension

• Hypertension is a common disorder encountered and
  diagnosed by many physicians.
• Because there is usually no pain associated with
  its occurrence , many patients are unaware of the
  problems until it is too late, as in the case of
  a stroke.

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OLE and hypertension

• An important component of OLE is oleuropeside.
• This compound has been shown to activate the
  vasodilation of blood vessels.
• This result in decreased arterial blood pressure,
  decreased atrial rate, decreased cardiac
  contractility and anti-arrhythmic effects.
• OLE ingredients act synergistically to potentiate
  the relaxant effect of oleuropeside.

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OLE and immune system

• If a persons immune system is overburdened in
  fighting a war against an influx of infectious
  germs, the immune system becomes weak and the
  body is more susceptible to sickness.
• When oleuropein is taken orally, 2 natural
  enzymes in the body, esterase and
  beta-glucosidase, convert the oleuropein to
  elolenic acid.
• Elolenic acid helps to strengthen the immune
  system.

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OLE and immune system

• The ingredients in OLE support and boost the
  immune system in 3 ways -
• 1 Interfering with the pathogens amino acid
  properties. This prevents the pathogen from
  reproducing and creating more microbes within the
  body. Studies has indicated that elolenic acid
  can enter infected cells in the body and stop
  viral cells from replicating.

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OLE and immune system

• Preventing virus shedding, the means by which
  viruses reproduce. Elolenic acid attaches to the
  cell membrane to stop viruses from multiplying
  and spreading. In the case of retroviruses,
  elolenic acid neutralizes the production of
  reverse transcriptase and protease. These enzymes
  are essential for a retrovirus, such as HIV, to
  alter the RNA of a healthy cell. Without them,
  the retrovirus is rendered impotent.
• 3. Directly stimulating phagocytosis, an immune
  system response in which cells ingest
  micro-organisms and foreign matter.

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OLE and energy increase

• OLE produces substantial energy.
• The likely reason for this is that the body is
  now freed from fighting so many opportunistic
  invaders.
• Without having to direct much of its energy
  inward for immune processes, the body can direct
  that energy level outwards to be used as desired.

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OLE and chronic fatigue

• Chronic Fatigue Syndrome is a rather prevalent
  condition of late.
• It is caused by the Epstein Barr virus, a member
  of the herpes family of viral infection that
  cause shingles and genital herpes.
• Symptoms of CFS include chronic fatigue as well
  as fever, sore throat, swollen glands, loss of
  appetite, insomnia, recurrent respiratory
  infections, nausea, intestinal problems, stomach
  ache, diarrhoea, anxiety, cough, depression, rash
  and skin problems, vomiting, mood swings,
  swelling, sleep problems, weight gain or loss,
  temporary memory loss, loss of concentration,
  unusual stress, headaches and other aches and
  pains.

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OLE and fibromyalgia

• Fibromyalgia is another syndrome that has been
  diagnosed with increasing frequency over the last
  few years.
• It is very much like Chronic Fatigue Syndrome
  with approximately 2 of the total population has
  fibromyalgia, while 20 of the female population
  between the ages of 40 and 60 years old age
  group.
• Fibromyalgia is a disorder that manifests itself
  in various parts of the body.

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OLE and fibromyalgia.

• The symptoms of fibromyalgia include aches,
  pains, stiffness, localised tenderness and
  swelling, fatigue, stress, headache, sore throat,
  intestinal problems, depressions, anxiety, memory
  blanks, loss of concentration, mood swings and
  non-refreshing sleep.
• Dr Walter Gunn states that this disease is some
  kind of immune dysfunction.

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OLE and fibromyalgia

• OLE empowers the immune system by increasing
  phagocytes, the bodys natural killer cells.
• OLE also has a proven record in vitro against
  viruses and latent viruses as well as numerous
  other pathogens.

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OLE and cardiovascular health

• OLE is well known and well documented to have a
  positive health benefit to the cardiovascular
  system.
• Petroni and Blasevich at the Institute of
  Pharmacological Studies, University of Milan
  found that OLE reduced blood platelet
  aggregation. This could potentially result in
  lessened risk of blood clots and heart problems.

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OLE and cardiovascular health

• In 1994, Petroni and Blasevichs partners at the
  University of Milan, F. Visioli and C. Galli
  showed that olive leaf derivatives are good
  antioxidants that prevent serious heart problems.
• V. Petkov while working on his research in Europe
  wrote several journals in the United States on
  the use of OLE in nutritionally maintaining
  healthy cardiovascular systems and helping other
  heart problems.
• In April 1995, Thrombosis Research reported the
  beneficial effect caused by the antioxidant
  properties in OLE.

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OLE and cholesterol

• Perez-Jimenez and Espino, in their 1995 article
  in the American Journal of Clinical Nutrition,
  demonstrated that OLE increased high density
  lipids or good cholesterol by 7.
• In 1994, experiments at the University of Milans
  Institute of Pharmacological Sciences found that
  OLE inhibited the oxidation of low-density
  lipoproteins, the so-called bad cholesterol
  connected to various heart problems.

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OLE and cholesterol

• In 1966 study by Ruiz-Gutierrez and Muriana at
  the University Hospital found that components in
  OLE boosted high-density lipids (good
  cholesterol) and reduced significantly the
  low-density lipids (bad cholesterol).

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OLE Nutritional support for the heart

• OLE helps solve the nutritional problems
  associated with a weakened cardiovascular system.
• Ribeiro and Fiuza reported in the Journal of
  Ethno-Pharmacology that OLE has the ability to
  lower blood pressure.
• Similarly, A. Zarzuelo and J. Duarte from
  Pharmacology Department at the University of
  Granada, Spain confirmed the findings that OLE is
  largely responsible for maintaining good
  cardiovascular system and the compound elolenic
  acid in OLE potentiates the presuure lessening
  action.

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OLE- Nutritional support for the heart.

• In 1996, study from the Hospital in Seville,
  Spain found that phenolic-rich OLE reduced both
  the systolic and diastolic blood presuures.
• OLE is a powerful antioxidant much like
  flavonoids and proanthocyanadins. These very
  compounds protect the heart and cardiovascular
  system from free-radical induced damage and
  promote good health.

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OLE and Colds Flus

• Eighty years ago, a flu swept the globe and
  killed 21 million people.
• The mortality rate was 10 times worse than the
  normal strain of influenza. New flu strain such
  as Birds flu, SARS caught the world by surprise.
• Many people had fevers of 104 C, and died died as
  their lungs filled with fluid.

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OLE and Colds Flus

• Many become delirious (disordered state of mind
  such as wild excitement, tremors, and terrifying
  delusions during feverish illness) before they
  died.
• In the US, 675,000 people died from the flu in
  less than a year.
• Many Americans fall prey to several colds every
  year. In 1990, 43.4 of Americans suffered
  through at least one type of flu, which is more
  than 110 million people missing from work, school
  and other aspects of their lives due infections

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OLE and Colds Flus

• Research has shown that OLE could substantially
  reduce ones susceptibility to cold or flu
  viruses.
• Dr Robert Lyons performed a clinical test of his
  patients using OLE. Of the 164 patients suffering
  from respiratory and lung conditions (colds, flu,
  lung problem and the like), 157 fully recovered
  and 7 improved while using OLE. Thats success
  rate of almost 96.
• OLE is a true germ killer since it selectively
  blocks an entire virus-specific system in the
  infected host. It is an organic health supplement
  that replaces pharmaceutical antibiotics !.

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OLE The Natural Antibiotic

• According to federal researchers, deaths from
  infectious disease rose by 58 from 1980 to 1992,
  in third place behind heart disease and cancer.
• WHO says that by the year 2000 other than Western
  technological medicine would be needed in order
  for all people to have adequate health care. WHO
  recommended the use of traditional forms of
  healing and medicine, such as the use of herbs ,
  to meet the demands of an exploding global
  population. The recommendation was adopted by WHO.

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OLE The Natural Antibiotic

• Most antibiotics suppress the immune system and
  nearly all of them destroy beneficial organisms
  in the intestinal tract.
• Antibiotics today render little use against most
  newly-named super-bug germs. With no new
  antibiotics on the horizon, this poses a grave
  threat to health.
• This is a big medical problem today that lead to
  disease epidemics largely as a result of overuse
  of antibiotics and many microbes are resistant to
  these medicines.

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OLE The Natural Antibiotic

• OLE empowers the immune system by directly
  stimulating production of the immune system cells
  called phagocytes. These phagocytes move
  throughout the body looking for foreign invaders.
  They then neutralize any abnormal organism that
  they find.

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OLE The Natural Antibiotic

• An important fact is that microbes cannot be
  resistant to phagocyte cells like they can to
  drug or antibiotic interventions.
• OLE contains flavonoids, esters and multiple
  iridoids that create a structurally complicated
  molecule.
• Micro-organisms cannot readily develop a
  resistance to OLEs complex structure.
• OLE does not disturb the beneficial bacteria in
  the intestines.

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OLE- The Natural Antibiotics

• Example OLE has shown itself to be the only
  effective and nutritional remedy available for
  the fatal Bacillus cereus contamination. This is
  a micro-organism that infects the body and there
  is no known medical treatment or cure once
  infected, it takes over the body and the person
  dies.
• Tassou and Nychas, researches at the Ministry of
  Agriculture in Athens, Greece detailed the
  results of their studies in the prestigious
  journals Lancet and Biotechnology Applied
  Biochemistry, stating that OLE and oleuropein
  inhibit the germination and growth of the
  pathogen.

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OLE and parasites

• We are living longer, but not healthier. Numerous
  authorities believe that a significant cause for
  this lack of health is the existence of
  parasites.
• Dr Hazel parcels states that 85 of adult North
  Americans are infected with parasites.
• WHO categorises parasites as among the 6 most
  harmful infectious diseases in humans.
• Parasites can inhabit muscle tissue, the
  digestive tract, the bloodstream and even the
  brain, heart and other vital organs.

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OLE and parasites.

• Parasites can be microscopic in size or can
  stretch up to 30 feet long.
• Most people think of parasites as tapeworms,
  hookworms, roundworms and flatworms. There are
  more than that.
• The Centre for Disease Control considers parasite
  caused Giardia to be the number one waterborne
  disease. It has been found in the water supplies
  of major cities in America.
• Giardia is one of the many microscopic organisms
  that can greatly interfere with physical and
  mental functioning. This parasite can coat the
  intestinal wall, inhibiting digestion and
  assimilation.

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OLE and parasites.

• Parasites can be contracted by eating undercooked
  beef, pork, fish or other meats, walking barefoot
  on infected soil, through intimate and casual
  physical contact, being in contact with flies or
  mosquitoes, eating unclean raw vegetables,
  drinking infected water, close physical contact
  with cats, dogs or other pets and simply
  contacting unclean environments through breathing
  or touching.

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OLE and parasites

• Current laboratory testing finds only about 1
  of the more than 1000 parasites that can live in
  the human body.
• Parasite infestations manifests itself in less
  obvious ways, many times hidden within the
  symptoms of various chronic health problems.

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OLE and parasites

• Problems caused by parasites include
  hypoglycemia, indigestion, a weakened immune
  system, fatigue or lack of energy, colitis, back
  pain, headaches, acne and other skin problems,
  poor assimilation, nausea, vomiting, lack of
  concentration, weakness, flu-like symptoms,
  muscle and joint pain, weight loss, a feeling of
  fullness in the stomach, appetite loss or
  uncontrolled appetite, gas, dizziness, memory
  loss, asthma, allergies, sinusitis, irritability,
  abdominal pain, menstrual problems and bed
  wetting.

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OLE and parasites

• Some researchers claim that the waste material
  produced by flukes is extremely carcinogenic and
  contributes to the formation of cancer.
• Microscopic parasites can cause arthritis-like
  symptoms.
• Parasites are notoriously difficult to kill and
  expel from the body. OLE exhibits powerful
  anti-parasitic action against parasites.

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OLE and dengue

• OLE is used in the treatment of tropical
  infections such as Malaria and Dengue.
• As far back as 1827, OLE has been used for the
  treatment of malaria.
• In 1906, one medical report stated that OLE is
  far more superior than quinine for malaria
  infections. In studies performed by Upjohn
  Company, elolenic acid, the substance within
  eleuropein was found to be effective against the
  malarial protozoa.

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OLE and food poisoning

• Mortimer and McCann, English researcher reporting
  in the May 1974 issue of Lancet, a prestigious
  medical journal found that fried rice , a Chinese
  dish was sometimes contaminated with the deadly
  Bacillus cereus bacteria and causes food
  poisoning.
• Symptoms include nausea, belching (sending out
  wind from stomach or through the mouth),
  flatulence (gas in the digestive tract),
  indigestion, oral frothing (foaming), vomiting,
  diarrhoea, burning stomach, sore abdomen,
  muscular weakness, pain in the upper body, heart
  damage, severe borne pain, body temperature
  fluctuations, mental confusion, extreme
  depression, abdominal distention (swelling),
  respiratory inflammation and permanent heart and
  lung damage.

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OLE and food poisoning

• OLE has been shown to be the only effective and
  nutritional remedy available for the fatal
  Bacillus cereus contamination.
• OLE contains flavonoids, esters and multiple
  iridoids that create a structurally complicated
  molecule that kill the bad micro-organism and
  does not disturb the beneficial bacteria in the
  intestines.

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OLE and Candida ,Yeast ,Fungus

• Candida albicans is a yeast which normally exists
  in a certain amount in the intestines. It is a
  symbiotic relationship normally it causes no
  problems in healthy people.
• However, once allowed to grow beyond this amount,
  in a situation called yeast overgrowth, problems
  begin.
• Candida enters newborn infants during or shortly
  after birth. By 6 months of age, 90 of all
  babies test positive for Candida.

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OLE and Candida

• Symptoms of Candidasis include fatigue, lethargy,
  depression, headaches, muscle aches or weakness,
  joint pain, abdominal pain, constipation,
  diarrhoea, gas, vaginal burning, itching or
  discharge, prostatisis, endometriosis,
  infertility,menstrual problems, PMS,
  anxiety,irritability. Drowsiness, lack of
  coordination, mood swings, insomnia, eczema,
  itching eyes, psoriasis, sensitivity to food,
  itching, cough, or recurrent bronchitis, urinary
  frequency or urgency, burning on urination,
  recurrent infections, inability to concentrate,
  skin problems, gastrointestinal symptoms, nervous
  system problems, recurrent yeast infections in
  women, allergies, sinus problems, recurrent colds
  and flu, indigestion, respiratory problems, food
  cravings, asthma and over or underweight.

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OLE and Candida

• Diets high in carbohydrates, sugar, yeast and
  yeast products, as well as moulds and fermented
  foods provide a ripe breeding ground for Candida.
• Prolonged exposure to moulds,antibiotics and
  sulfa drugs also pose a threat.
• For women, taking birth control pills or having
  multiple pregnancies can raise or lower bodys pH
  level to provide a favourable environment for the
  growth of Candida.
• Stress, poor nutrition, pollution, steroids,
  antibiotics and hormones in meat and milk
  products may also be a contributing cause.