Abstract: Selfassembly is beginning to be seen as a practical vehicle for computation. The assembly

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Abstract Self-assembly is beginning to be seen
as a practical vehicle for computation. The
assembly of DNA-based tiles into 2D periodic
arrays had been reported several times with a
variety of motifs. In our work, one layer of
self-assembled DNA 2-D array will be used as the
programmable template. Sequence dependent
nano-mechanical DNA devices will be inserted
into the array. Each device can enter into a
bi-stable state, and that this state could be
controlled as well by the sequences of DNA. This
system can lead to the computation of an
arbitrary boolean function or creation of 2D DNA
layers satisfying specific properties.
A DNA Motif to Insert a Sequence-Driven Device
into a DNA Array
Baoquan Ding, Nadrian Seeman
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Structures of of the 2 states of the
Sequence-Driven DNA Devices
TPX TJX
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Molecular Models of the 2 states of the
Sequence-Driven DNA Devices
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Simple Model of the Device and the Inserting into
Array
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Model of the Array that Contain Different State
Devices
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Electrophoresis Analysis of the Formation of the
Device
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Electrophoresis Analysis of Operation of the
Device
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TX 2D DNA Array that Works as the Template
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2D Array with Protruding Marker Tiles
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One State of Modified Device that Will be
Inserted into Array
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Template Array that Contain Different States
Devices
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Summary Sequence-driven DNA devices that will
be inserted into 2D DNA array have been
constructed. The template array has been
designed, and construction and AFM analysis are
currently in progress.