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CYTOMEGALOVIRUS INFECTION

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... types 1 & 2, varicella-zoster virus (chickenpox) and Epstein-Barr virus (which ... Found universally throughout all geographic locations and socioeconomics groups ... – PowerPoint PPT presentation

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Title: CYTOMEGALOVIRUS INFECTION


1
CYTOMEGALOVIRUS INFECTION
2
What is Cytomegalovirus?
  • Cytomegalovirus (CMV) is a member of the herpes
    virus group, which includes herpes simplex virus
    types 1 2, varicella-zoster virus (chickenpox)
    and Epstein-Barr virus (which causes
    mononucleosis)
  • Found universally throughout all geographic
    locations and socioeconomics groups
  • Infects between 50 and 85 of adults in the
    United States by 40 years of age
  • Virus most frequently transmitted to a child
    before birth

3
High-Risk Groups
  • The unborn child during pregnancy
  • People who work with children
  • Immunocompromised person, such as an organ
    transplant recipients and person infected with HIV

4
Contact/Spreading of the Virus
  • Infectious CMV may be shed in the bodily fluids
    of any previously infected person, and thus may
    be found in urine, saliva, blood, tears, semen
    and breast milk.
  • Shedding of the virus may take place
    intermittently, without any detectable signs, and
    without causing symptoms.

5
Lab Work
  • Blood sample, taken upon suspicion of CMV, and
    another one taken within 2 weeks
  • Virus culture can be performed at any time the
    patient is symptomatic
  • Other lab work include urine, throat swabs, and
    tissue samples

6
Symptoms of Cytomegalovirus
  • Fever
  • Sore throat
  • Red tonsils
  • Enlarged lymph nodes
  • Mild-like Hepatitis
  • Mononucleosis-like symptoms

7
Mononucleosis-Mouth Sore throat and red tonsils
8
Outcome of Cytomegalovirus
  • Currently no treatment exists for CMV infection
    in the healthy individual.
  • Antiviral therapy is now being evaluated in
    infants.
  • Ganicilovir treatment is used for patients with
    depressed immunity who have either sight-related
    or life-threatening illnesses.
  • Vaccines are still in research and development
    stage
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