Genetic Control of Temperature

1
Genetic Control of Temperature Preference in the
Nematode Caenorhabditis elegans
Akiko Mohri, Elji Kodama, Koutarou Kimura, Mizuho
Koike, Takafumi Mizuno and Ikue Mori
2
Background

• Worms will migrate to cultivation temperature
  when on a temperature gradient (HR, 1975)
• Worm will avoid temperatures paired with
  starvation
• If E. coli paired with new temperature, take 2-4
  hours before worms will migrate to the new
  temperature

3
Neural circuit
Mori 1995
4
(No Transcript)
5
Figure 1
6
Table 1
7
Figure 2
8
Figure 3
9
Figure 4
10
Figure 5
11
Figure 6
12
Figure 7
13
Figure 8
14
(No Transcript)
15
Figure 10
16
Figure 11
17
Figure 12
18
Conclusions

• Respond differently to changes in temperature vs.
  feeding state
• aho-2 defective thermotactic avoidance