Diapositiva 1

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October 1996-March 2003 University Degree in
Pharmaceutical Chemistry and Tecnology,
University of Padua, Padua, Italy (Prof. Michael
Wiese and Prof. Stefano Moro, Advisors).
Defending an experimental thesis titled
Development of a pharmacophore model of
selective dopamine D1-antagonists
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March 2002-December 2002 D. Research under
SOCRATES/ERASMUS Program at the Department of
Pharmaceutical Chemistry, University of Bonn,
(Prof. Michael Wiese, Advisor).
Research focused on Ligand-based drug design and
pharmacophore model development on D1 receptor.
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May 2003-May 2004 Scholarship provided by MIUR
(Ministero dellIstruzione, dellUniversità e
della Ricerca), University of Padua, Padua,
Italy. (Prof. Stefano Moro, Advisor)

• Research focused on
• Molecular simplification strategy in the
  discovery of new Topoisomerase I poisons from
  bioactive natural camptothecin.

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Research focused on

• Combined target-based (molecular docking) and
  ligand based drug design (CoMFA) to define a
  novel pharmacophore model of the human A3
  antagonists.
• Moro S., Braiuca P., Deflorian F., Pastorin G.,
  Ferrari C., Cacciari B., Varani K., Gessi S.,
  Borea P.A., Baraldi P.G., Spalluto G.,
  J.Med.Chem. 2005 48(1)152-62

• Autocorrelation of molecular electrostatic
  potential surface properties combined with
  partial least squares analysis as alternative
  attractive tool to generate ligand-based 3D-QSAR.
• Moro S., Bacilieri M., Ferrari C., Spalluto G.
  Current Drug Discovery Technologies 2005 2
  13-21

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• June 2004-October 2004 Internship at S.IN.
• (Soluzioni Informatiche, Vicenza, Italy,
  www.s-in.it).
• Research focused on
• Different approaches to predict HERG affinity
  values.
• Fioravanzo E., Cazzolla N., Durando L., Ferrari
  C., Mabilia M., Ombrato R., Parenti M.D.,
  (Internet Electronic Conference of Molecular
  Design 2004, IECMD 2004, November 29-December 12)
• High Throughput molecular docking on PPAR?.

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November 2004-Present Ph.D. Student in
Computational Chemistry, University of Perugia,
Italy. (Prof. Gabriele Costantino, Prof. Roberto
Pellicciari, Advisors). Research focused on

• Essential Dynamics studies of Nuclear Receptors.
• Ligand-based drug design, pharmacophore model
  development on FPRs receptors and binding mode
  analysis of the antagonists.
• Ferrari C., Macchiarulo A.,Pellicciari R.,
  Journal of Computer-Aided Molecular Design.
  (submitted)

• Virtual screening of published databases on
  different targets.
• (Internship at Sienabiotech, Siena, Italy)