Biomolecular Adsorption Van Tassel Group Projects at Yale University

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Biomolecular Adsorption Van Tassel Group
Projects at Yale University
Multilayer Nanofilm Biomaterials
Protein-Polyelectrolyte Adsorption under Electric
Potential
Cell
(rinse)
DV
Adhesion molecule
DV 1.5 V
Film Mass mg/cm2
Growth factor
Polyelectrolyte
DV 0
- Polyelectrolyte
Biomaterial

• Areas of focus
• Kinetics of adsorption
• Multilayer / cell interactions
• Liver tissue engineering

• Collaborators
• Mark Saltzman
• Diane Krause
• Martha Harding

Funding NIH R01-EB00258

• Areas of focus
• Continuous adsorption under voltage
• Protein / nanoparticle incorporation

Funding NSF CTS-9733310 NIH R01-EB00258
Templated Molecular Recognition
Macro-Ion Influence on Colloidal Force
Macro-ion


Colloidal Particle
Surface

• Areas of focus
• Steric / energetic templating
• Integral equation approach
• Biomaterial applications

Funding NSF CTS-9876599 NSF CTS-0337829 ACS PRF
34163-G9

• Areas of focus
• Macro-ion charge / shape
• AFM / TIRM expt. MC / DFT calc.
• Biosensing / bioassay applications

• Collaborators
• John Walz

Funding NSF CTS-0434777 NSF CTS-0621485