Path Dependence

1
Path Dependence

• Phil Cooke
• Centre for Advanced Studies CESAGen
• Cardiff University

2
Basel, Path Dependence, Pharma, Globalisation

• Long Timelines
• Competitive Strategies of Emulation
• Public Research Infrastructure
• Basel-Freiburg-Strasburg BioValley agro-food
  pharmaceutical biotechnology
• Basel has 52 biotech spinouts (26 Swiss total)
• Global Biotech Cluster Penetration

3
Basel Pharma Timelines ( Nobels)
4
Basel Research Capabilities
5
Novartis in San Diego
6
Roche in San Francisco San Diego
7
Novartis in Cambridge Boston
8
Conclusions

• Swiss pharma the most aggressive
  collaborator/acquirer in US biotech
• Global cluster-based division of capabilities
• Basel for cardiovascular oncology
• San Diego for immunology (HIV etc.)
• San Francisco for gene therapies/technologies
• Cambridge/Boston for post-genomics transgenics
• Syngenta in San Diego and RTP, N. Carolina
• Strategic accessing of Regional Knowledge
  Capabilities
• Path Dependence Strategically Evolved