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PHYSIOLOGY OF THE PANCREAS

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Stimulates glycogenesis. Stimulates glycolysis. Stimulates HMP shunt activity ... Stimulates glycogenesis. Stimulates glycolysis. Inhibits glycogenolysis ... – PowerPoint PPT presentation

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Title: PHYSIOLOGY OF THE PANCREAS


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PHYSIOLOGY OF THE PANCREAS
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Actions of Insulin on the Liver
  • Stimulates glucose uptake
  • Stimulates glycogenesis
  • Stimulates glycolysis
  • Stimulates HMP shunt activity
  • Inhibits glycogenolysis
  • Inhibits gluconeogenesis
  • Stimulates lipogenesis
  • Inhibits lipolysis
  • Stimulates cholesterol synthesis
  • Increases VLD lipoprotein
  • Increases potassium and phosphate uptake

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Actions of Insulin on Muscle
  • Stimulates glucose uptake
  • Stimulates glycogenesis
  • Stimulates glycolysis
  • Inhibits glycogenolysis
  • Inhibits FFA uptake and oxidation
  • Stimulates proteogenesis
  • Inhibits proteolysis
  • Stimulates uptake of potassium, phosphate and
    magnesium
  • Increases blood flow

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Action of Insulin on Adipose Tissue
  • Stimulates glucose uptake
  • Stimulates glycolysis
  • Stimulates lipogenesis
  • Inhibits lipolysis and ketogenesis

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Actions of Glucagon on the Liver
  • Stimulates glycogenolysis
  • Stimulates gluconeogenesis
  • Inhibits glycolysis
  • Stimulates lipolysis and ketogenesis
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