Compare and contrast pharmacogenetics and pharmacogenomics ... Patient buccal swab (sample) SNP Screening. Results. Results. Analysis. Data Management: ...
The Pharmacogenetics of Warfarin: Assessing quality of studies in ... many smaller, some severely underpowered studies advised ... Underpowered studies with ...
Causes:excessive smoking, caffeine, or alcohol use; digitalis toxicity,and so on. It occurs ... digitalis 2. blood thinners, such as heparin or Warfarine, ...
Title: PowerPoint Presentation Author: Peter Loewen Last modified by: Tim Rogers Created Date: 9/29/2006 3:43:35 PM Document presentation format: On-screen Show
Monitoring Drug Efficacy & Toxicity - along with drug metabolism Michael E. Hodsdon, MD, PhD Associate Professor Departments of Laboratory Medicine & Pharmacology
Readily exreted by the kidney when surpassing the renal threshold - toxicity is rare ... hypercalcemia with hypercalciuria (!stones), bone demineralization. Vitamin E ...
... With Data Suggesting Efficacy Safe Herbals With Data Suggesting Efficacy Co-Enzyme Q-may decrease INR while on warfarin Chamomile-may increase INR if on ...
Drug Biotransformation Elimination of the drugs Drug Biotransformation Metabolism or biotransformation - complex of processes which provide decreasing of toxicity and ...
Prescription Drug Use Among Community ... Consumption of 'high risk' drugs: e.g., warfarin, digoxin, cimetidine, phenytoin, ... Anticholinergic drugs and BPH ...
Urinary Retention. prolonged use of an indwelling urinary ... Treatable causes. hypoxia, infection, fluid and electrolyte abnormalities, drug toxicity, and ...
nothing unique about 'toxic' chemicals. Illustrations: Hormone mimics. Bioremediation ... Can increase or reduce toxicity by supplementing or removing toxic form ...
1. Short Acting Warfarin. 2. Long Acting---Diphacenone, ... and progressive ataxia, paresis, hind leg paralysis, progressive CNS depression and coma. ...
used for control of various pests. General Considerations. Substances used to kill unwanted 'pests' Algae-, herb-, insect-, rodent- Selective toxicities ...
Repeating polymer of uronic acid and glucosamine. Highly heterogeneous in terms of sulfation and ... Warfarin-induced Venous Limb Gangrene. in HIT Patients ...
SOME FACTS AND STATISTICS. Factors to drug responses: ... Linder MW Ph.D. DABCC, Manage the 'Over-steer' in warfarin dose titration. VKORC1 POLYMORPHISM ...
Posterior fossa surgery. Aspirin. Warfarin. Closure. PFO WITH LARGE SHUNT (shower or curtain) ... Fossa ovalis diameter. PFO tunnel. Rims: SA, IP, SP & IA rim ...
The RE-LY Study: Randomized Evaluation of Long-term anticoagulant therapY Dabigatran Compared to Warfarin in 18,113 Patients with Atrial Fibrillation at Risk of Stroke
'An antagonist is a substance that does not provoke a biological response itself, ... Example: phenobarbital accelerates the rate of metabolic degradation of warfarin ...
Previous induction of antibodies (100 d) Rare. Heparin absent ... (2) administering IV vitamin K to patients on warfarin. Efficacy of Direct Thrombin Inhibitors ...
After one week , the patient accidently but lightly bumped her arm on the side ... After investigation ,the physcian discovered that this herbal coktail ...
Chapter 16 NSAIDs and COX-2-Selective Inhibitors Jeffrey A. Katz, M.D. R2 Lee Seung Il Mechanism of Action Prostaglandin Physiology Hyperalgesia (1) sensitize ...
Small separation between dose-response curves for preventing emboli and excess coagulation ... Elderly woman in nursing home -Sent to ER with lower GI bleed -Dx ...
Heparin first used in vascular surgery 1930's. LMWH approved ... agent for LMWH for prophylaxis or initial treatment of venous thromboembolism. Treatment of HIT ...
Historical Development of Toxicology It is one of the oldest practical sciences which began with early cave dwellers who recognized poisonous plants and animals and ...
drug clearance mechanisms (renal and hepatic) are limited in newborns ... reduced hepatic blood flow. reduced activities of cytochrome P450 enzymes. gender ...
Antimicrobial Agents (Aminoglycosides, tetracyclines, macrolides and other assorted drugs) Dr. Jeff Hobden MIP The Aminoglycosides Two or more amino sugars attached ...
Pesticides Aquatic Ecotoxicology Lecture November 19, 2003 Dr. Matt Moore USDA Agricultural Research Service National Sedimentation Laboratory Oxford, Mississippi
... but interfere with the pharmacokinetic ... nephrotoxicity Cyclosporine Methotrexate Triamterene Tacrolimus Aminoglycosides Increased GI bleed SSRIs ...
Non-Steroidal Anti-Inflammatory Drugs ibuprofen Meghin Gjerswold 12.01.2006 UWSOP at Genelex NSAID use NSAIDs are available OTC NSAIDs can be toxic on their own ...
HERBAL MEDICINES ANESTHETIC IMPLICATIONS M. Ron Eslinger CRNA, MA, APN www.aamsn.com A 35 year old athletic woman with a history of migraines presents for ACL ...
Assessment of Efficacy and Safety for Exanta (Ximelagatran) Ruyi He, M.D. Medical Team Leader The Division of Gastrointestinal and Coagulation Drug Products
Antiplatelet and anticoagulant therapy in stroke prevention Dr Sepehr Shakib Director Clinical Pharmacology Royal Adelaide Hospital Aspirin + Dipyridamole ...
Tuberculosis is an infectious lung disease caused by bacteria that spreads through the air through coughing, sneezing, or spitting. In this presentation "Treatment of Tuberculsois (TB)" has been described including their causes, therapy, Principles, diagnosis, symptoms, management, etc. For more information, please contact us: 9779030507.
AV node receives more impulses than it can conduct. Most impulses are ... Haemophilia. Liver Failure. Renal Failure. Peptic Ulcer. Oesophagal varices. Aneurysm ...
NSAIDs and COX-2-Selective Inhibitors R3 History and Background NSAIDs Most often used nonopiod analgesics 70 million prescriptions were given in 1991 $2.2 ...