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DRUG TOXICITY PowerPoint PPT Presentation
DRUG TOXICITY - MED - For: barbiturate anaesthesia 3-4. benzodiazepines 20 ... sedation, general anaesthesia. enhancement of GABAA receptor function. ketamine ...
MED - For: barbiturate anaesthesia 3-4. benzodiazepines 20 ... sedation, general anaesthesia. enhancement of GABAA receptor function. ketamine ...
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Warfarin Dosing PowerPoint PPT Presentation
Warfarin Dosing - Compare and contrast pharmacogenetics and pharmacogenomics ... Patient buccal swab (sample) SNP Screening. Results. Results. Analysis. Data Management: ...
Compare and contrast pharmacogenetics and pharmacogenomics ... Patient buccal swab (sample) SNP Screening. Results. Results. Analysis. Data Management: ...
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DRUG TOXICITY PowerPoint PPT Presentation
DRUG TOXICITY - Toxicology is the science that deals with the amount of an agent that causes an ... MED - For: barbiturate anaesthesia 3-4. benzodiazepines 20 ...
Toxicology is the science that deals with the amount of an agent that causes an ... MED - For: barbiturate anaesthesia 3-4. benzodiazepines 20 ...
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Hematologic and Immunologic Toxicity PowerPoint PPT Presentation
Hematologic and Immunologic Toxicity - Failure to reduce heme iron to ferrous state. Methemoglobinemia ... Spleen. Lymph nodes. Diffuse tissues. Tonsils. GALT. Immune Cell Function. GRANULOCYTES ...
Failure to reduce heme iron to ferrous state. Methemoglobinemia ... Spleen. Lymph nodes. Diffuse tissues. Tonsils. GALT. Immune Cell Function. GRANULOCYTES ...
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Serious Cardiac Arrhythmia PowerPoint PPT Presentation
Serious Cardiac Arrhythmia - Causes:excessive smoking, caffeine, or alcohol use; digitalis toxicity,and so on. It occurs ... digitalis 2. blood thinners, such as heparin or Warfarine, ...
Causes:excessive smoking, caffeine, or alcohol use; digitalis toxicity,and so on. It occurs ... digitalis 2. blood thinners, such as heparin or Warfarine, ...
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The Pharmacogenetics of Warfarin: Assessing quality of studies in systematic review PowerPoint PPT Presentation
The Pharmacogenetics of Warfarin: Assessing quality of studies in systematic review - The Pharmacogenetics of Warfarin: Assessing quality of studies in ... many smaller, some severely underpowered studies advised ... Underpowered studies with ...
The Pharmacogenetics of Warfarin: Assessing quality of studies in ... many smaller, some severely underpowered studies advised ... Underpowered studies with ...
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Anticoagulation post STEMI: warfarin for wall motion abnormality in the era of triple antithrombotics PowerPoint PPT Presentation
Anticoagulation post STEMI: warfarin for wall motion abnormality in the era of triple antithrombotics - Title: PowerPoint Presentation Author: Peter Loewen Last modified by: Tim Rogers Created Date: 9/29/2006 3:43:35 PM Document presentation format: On-screen Show
Title: PowerPoint Presentation Author: Peter Loewen Last modified by: Tim Rogers Created Date: 9/29/2006 3:43:35 PM Document presentation format: On-screen Show
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Top 10 dangerous Drug Interactions PowerPoint PPT Presentation
Top 10 dangerous Drug Interactions - AMDA and ASCP summarised top 10 danferous drug interactions involving Warfarin, ACE inhibitors, Digoxin or Theophylline with other drugs
AMDA and ASCP summarised top 10 danferous drug interactions involving Warfarin, ACE inhibitors, Digoxin or Theophylline with other drugs
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Monitoring Drug Efficacy PowerPoint PPT Presentation
Monitoring Drug Efficacy - Monitoring Drug Efficacy & Toxicity - along with drug metabolism Michael E. Hodsdon, MD, PhD Associate Professor Departments of Laboratory Medicine & Pharmacology
Monitoring Drug Efficacy & Toxicity - along with drug metabolism Michael E. Hodsdon, MD, PhD Associate Professor Departments of Laboratory Medicine & Pharmacology
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Drug Interactions in the Heart/ Lung Transplant Patient PowerPoint PPT Presentation
Drug Interactions in the Heart/ Lung Transplant Patient - ... With Data Suggesting Efficacy Safe Herbals With Data Suggesting Efficacy Co-Enzyme Q-may decrease INR while on warfarin Chamomile-may increase INR if on ...
... With Data Suggesting Efficacy Safe Herbals With Data Suggesting Efficacy Co-Enzyme Q-may decrease INR while on warfarin Chamomile-may increase INR if on ...
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Pharmaceutical Waste Management PowerPoint PPT Presentation
Pharmaceutical Waste Management - Organic Wastewater Contaminants (OWCs) found in 80% of streams tested ... Nicotine, Nitroglycerin, Phentermine, Physostigmine, Warfarin, Arsenic trioxide (chemo drug) ...
Organic Wastewater Contaminants (OWCs) found in 80% of streams tested ... Nicotine, Nitroglycerin, Phentermine, Physostigmine, Warfarin, Arsenic trioxide (chemo drug) ...
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HOW COMMITTED ARE YOU? PowerPoint PPT Presentation
HOW COMMITTED ARE YOU? - ... Emergencies causing the blood to be dark brown in color Toxicologic Emergencies Metals Lead toxicity more common in dogs ... Acute renal failure ...
... Emergencies causing the blood to be dark brown in color Toxicologic Emergencies Metals Lead toxicity more common in dogs ... Acute renal failure ...
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Trials of Antithrombotic Therapy in AF  PowerPoint PPT Presentation
Trials of Antithrombotic Therapy in AF - ACC/AHA/ESC AF Guidelines (1) Author: Information Systems Last modified by: ... Control to Prevent Stroke in AF* Efficacy of Anticoagulation for AF Warfarin for AF: ...
ACC/AHA/ESC AF Guidelines (1) Author: Information Systems Last modified by: ... Control to Prevent Stroke in AF* Efficacy of Anticoagulation for AF Warfarin for AF: ...
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Fat Soluble Vitamins and Health PowerPoint PPT Presentation
Fat Soluble Vitamins and Health - Fat Soluble Vitamins and Health Overdoses and Toxicity of Vitamin E Doses greater than 800-1500iu/day may increase mortality due to all causes.
Fat Soluble Vitamins and Health Overdoses and Toxicity of Vitamin E Doses greater than 800-1500iu/day may increase mortality due to all causes.
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Drug Biotransformation PowerPoint PPT Presentation
Drug Biotransformation - Drug Biotransformation Elimination of the drugs Drug Biotransformation Metabolism or biotransformation - complex of processes which provide decreasing of toxicity and ...
Drug Biotransformation Elimination of the drugs Drug Biotransformation Metabolism or biotransformation - complex of processes which provide decreasing of toxicity and ...
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Vitamins PowerPoint PPT Presentation
Vitamins - Readily exreted by the kidney when surpassing the renal threshold - toxicity is rare ... hypercalcemia with hypercalciuria (!stones), bone demineralization. Vitamin E ...
Readily exreted by the kidney when surpassing the renal threshold - toxicity is rare ... hypercalcemia with hypercalciuria (!stones), bone demineralization. Vitamin E ...
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A Pharmacogenomic Approach to Understanding PowerPoint PPT Presentation
A Pharmacogenomic Approach to Understanding - Pharmacogenomics as a Model for Association Studies ... Rare non-synonymous mutations in VKORC1 causative for warfarin resistance (15-35 mg/d) ...
Pharmacogenomics as a Model for Association Studies ... Rare non-synonymous mutations in VKORC1 causative for warfarin resistance (15-35 mg/d) ...
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Drug use in the elderly PowerPoint PPT Presentation
Drug use in the elderly - Drug use in the elderly HOW TO PRESCRIBE APPROPRIATELY Know the actions, adverse effects, and toxicity profiles of the medications you prescribe.
Drug use in the elderly HOW TO PRESCRIBE APPROPRIATELY Know the actions, adverse effects, and toxicity profiles of the medications you prescribe.
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Dr. Randa Al-Harizy PowerPoint PPT Presentation
Dr. Randa Al-Harizy - ATRIAL FIBRILLATION Atrial Arrhythmias Management When atrial fibrillation is due to an acute precipitating event such as alcohol toxicity, chest ...
ATRIAL FIBRILLATION Atrial Arrhythmias Management When atrial fibrillation is due to an acute precipitating event such as alcohol toxicity, chest ...
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MEDICATION USE IN OLDER ADULTS PowerPoint PPT Presentation
MEDICATION USE IN OLDER ADULTS - Prescription Drug Use Among Community ... Consumption of 'high risk' drugs: e.g., warfarin, digoxin, cimetidine, phenytoin, ... Anticholinergic drugs and BPH ...
Prescription Drug Use Among Community ... Consumption of 'high risk' drugs: e.g., warfarin, digoxin, cimetidine, phenytoin, ... Anticholinergic drugs and BPH ...
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Upside-Down and Other Unusual Dose Responses and The Implications for Occupational Exposures PowerPoint PPT Presentation
Upside-Down and Other Unusual Dose Responses and The Implications for Occupational Exposures - nothing unique about 'toxic' chemicals. Illustrations: Hormone mimics. Bioremediation ... Can increase or reduce toxicity by supplementing or removing toxic form ...
nothing unique about 'toxic' chemicals. Illustrations: Hormone mimics. Bioremediation ... Can increase or reduce toxicity by supplementing or removing toxic form ...
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Medical Care of Patients with Hip Fractures PowerPoint PPT Presentation
Medical Care of Patients with Hip Fractures - Urinary Retention. prolonged use of an indwelling urinary ... Treatable causes. hypoxia, infection, fluid and electrolyte abnormalities, drug toxicity, and ...
Urinary Retention. prolonged use of an indwelling urinary ... Treatable causes. hypoxia, infection, fluid and electrolyte abnormalities, drug toxicity, and ...
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Diapositiva 1 PowerPoint PPT Presentation
Diapositiva 1 - CRP. Normal Endothelium. Dysfunctional Endothelium ... CD40L/CRP. Inhibitors of the intrinsic pathway. HEPARIN. WARFARIN. LOW MOLECULAR WEIGHT HEPARINS ...
CRP. Normal Endothelium. Dysfunctional Endothelium ... CD40L/CRP. Inhibitors of the intrinsic pathway. HEPARIN. WARFARIN. LOW MOLECULAR WEIGHT HEPARINS ...
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Complementary PowerPoint PPT Presentation
Complementary - 'Natural' Medicine. Direct toxicity occurs. Indirect effects ... Have you used any herbal or natural remedies that you have bought from a ...
'Natural' Medicine. Direct toxicity occurs. Indirect effects ... Have you used any herbal or natural remedies that you have bought from a ...
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Anticoagulants and HIT PowerPoint PPT Presentation
Anticoagulants and HIT - Repeating polymer of uronic acid and glucosamine. Highly heterogeneous in terms of sulfation and ... Warfarin-induced Venous Limb Gangrene. in HIT Patients ...
Repeating polymer of uronic acid and glucosamine. Highly heterogeneous in terms of sulfation and ... Warfarin-induced Venous Limb Gangrene. in HIT Patients ...
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Second Semester Pharmacology Orientation PowerPoint PPT Presentation
Second Semester Pharmacology Orientation - ... Arixtra (fondaparinux); Fragmin (dalteparin) Typically used post-operatively and short-term Must have stop date PO Coumadin (warfarin, jantoven); ...
... Arixtra (fondaparinux); Fragmin (dalteparin) Typically used post-operatively and short-term Must have stop date PO Coumadin (warfarin, jantoven); ...
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Cantharidin PowerPoint PPT Presentation
Cantharidin - 1. Short Acting Warfarin. 2. Long Acting---Diphacenone, ... and progressive ataxia, paresis, hind leg paralysis, progressive CNS depression and coma. ...
1. Short Acting Warfarin. 2. Long Acting---Diphacenone, ... and progressive ataxia, paresis, hind leg paralysis, progressive CNS depression and coma. ...
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Plasma and Cellular Elements of Blood PowerPoint PPT Presentation
Plasma and Cellular Elements of Blood - Malaria connection: RBCs loose potassium which is essential for survival of parasite (plasmodium) Coumarin and warfarin block Vit K action ...
Malaria connection: RBCs loose potassium which is essential for survival of parasite (plasmodium) Coumarin and warfarin block Vit K action ...
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Pharmacogenomics and Therapy Dosing PowerPoint PPT Presentation
Pharmacogenomics and Therapy Dosing - SOME FACTS AND STATISTICS. Factors to drug responses: ... Linder MW Ph.D. DABCC, Manage the 'Over-steer' in warfarin dose titration. VKORC1 POLYMORPHISM ...
SOME FACTS AND STATISTICS. Factors to drug responses: ... Linder MW Ph.D. DABCC, Manage the 'Over-steer' in warfarin dose titration. VKORC1 POLYMORPHISM ...
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PESTICIDES PowerPoint PPT Presentation
PESTICIDES - used for control of various pests. General Considerations. Substances used to kill unwanted 'pests' Algae-, herb-, insect-, rodent- Selective toxicities ...
used for control of various pests. General Considerations. Substances used to kill unwanted 'pests' Algae-, herb-, insect-, rodent- Selective toxicities ...
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PERCUTANEOUS CLOSURE OF PFO: State of the art PowerPoint PPT Presentation
PERCUTANEOUS CLOSURE OF PFO: State of the art - Posterior fossa surgery. Aspirin. Warfarin. Closure. PFO WITH LARGE SHUNT (shower or curtain) ... Fossa ovalis diameter. PFO tunnel. Rims: SA, IP, SP & IA rim ...
Posterior fossa surgery. Aspirin. Warfarin. Closure. PFO WITH LARGE SHUNT (shower or curtain) ... Fossa ovalis diameter. PFO tunnel. Rims: SA, IP, SP & IA rim ...
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Anticoagulants PowerPoint PPT Presentation
Anticoagulants - Binds to the plasma protein antithrombin ... Warfarin-induced Venous Limb Gangrene. Warkentin et al., Ann Intern Med 1997; 127: 804 ...
Binds to the plasma protein antithrombin ... Warfarin-induced Venous Limb Gangrene. Warkentin et al., Ann Intern Med 1997; 127: 804 ...
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Herb-drug interactions PowerPoint PPT Presentation
Herb-drug interactions - Herb-drug interactions Charlotte Gyllenhaal, Ph.D. ... Saw palmetto lipid extract. Case report of intraoperative hemorrhage (w/o warfarin) ...
Herb-drug interactions Charlotte Gyllenhaal, Ph.D. ... Saw palmetto lipid extract. Case report of intraoperative hemorrhage (w/o warfarin) ...
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The RE-LY Study: Randomized Evaluation of Long-term anticoagulant therapY PowerPoint PPT Presentation
The RE-LY Study: Randomized Evaluation of Long-term anticoagulant therapY - The RE-LY Study: Randomized Evaluation of Long-term anticoagulant therapY Dabigatran Compared to Warfarin in 18,113 Patients with Atrial Fibrillation at Risk of Stroke
The RE-LY Study: Randomized Evaluation of Long-term anticoagulant therapY Dabigatran Compared to Warfarin in 18,113 Patients with Atrial Fibrillation at Risk of Stroke
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HIV drug interactions Meds used in Neuropsych PowerPoint PPT Presentation
HIV drug interactions Meds used in Neuropsych - Step 3 Searching by: Pethidine (Meperidine) Step 4 View results ... Lopinavir Pethidine (Meperidine) Source: hiv-druginteractions.org (liverpool) Warfarin ...
Step 3 Searching by: Pethidine (Meperidine) Step 4 View results ... Lopinavir Pethidine (Meperidine) Source: hiv-druginteractions.org (liverpool) Warfarin ...
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A Look at the Increased Use of Dietary Supplements Among Youth PowerPoint PPT Presentation
A Look at the Increased Use of Dietary Supplements Among Youth - Dietary Supplement Health and Education Act of 1994: ... Interactions with prescription drugs. Warfarin. Ginkgo biloba. Vitamin E. St. John's Wart ...
Dietary Supplement Health and Education Act of 1994: ... Interactions with prescription drugs. Warfarin. Ginkgo biloba. Vitamin E. St. John's Wart ...
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DENS 211 Pharmacology PowerPoint PPT Presentation
DENS 211 Pharmacology - 'An antagonist is a substance that does not provoke a biological response itself, ... Example: phenobarbital accelerates the rate of metabolic degradation of warfarin ...
'An antagonist is a substance that does not provoke a biological response itself, ... Example: phenobarbital accelerates the rate of metabolic degradation of warfarin ...
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Anticoagulants and HIT PowerPoint PPT Presentation
Anticoagulants and HIT - Previous induction of antibodies (100 d) Rare. Heparin absent ... (2) administering IV vitamin K to patients on warfarin. Efficacy of Direct Thrombin Inhibitors ...
Previous induction of antibodies (100 d) Rare. Heparin absent ... (2) administering IV vitamin K to patients on warfarin. Efficacy of Direct Thrombin Inhibitors ...
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Antimicrobial Agents (General considerations) PowerPoint PPT Presentation
Antimicrobial Agents (General considerations) - Antimicrobial Agents (General considerations) Prof. R. K. Dixit Pharmacology and Therapeutics K.G.M.U. Lucknow dixitkumarrakesh@gmail.com Objectives .
Antimicrobial Agents (General considerations) Prof. R. K. Dixit Pharmacology and Therapeutics K.G.M.U. Lucknow dixitkumarrakesh@gmail.com Objectives .
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Drug affecting blood & its formation PowerPoint PPT Presentation
Drug affecting blood & its formation - information about blood and anticoagulant drugs.
information about blood and anticoagulant drugs.
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Randomized Evaluation of Long-term anticoagulant therapY PowerPoint PPT Presentation
Randomized Evaluation of Long-term anticoagulant therapY - Phase 2 data identified 110 mg BID and 150 mg BID as viable doses ... Net Clinical Benefit includes vascular events, death and major bleed ...
Phase 2 data identified 110 mg BID and 150 mg BID as viable doses ... Net Clinical Benefit includes vascular events, death and major bleed ...
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Anticoagulants drugs interactions PowerPoint PPT Presentation
Anticoagulants drugs interactions - After one week , the patient accidently but lightly bumped her arm on the side ... After investigation ,the physcian discovered that this herbal coktail ...
After one week , the patient accidently but lightly bumped her arm on the side ... After investigation ,the physcian discovered that this herbal coktail ...
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Biomedical Informatics and Interdisciplinary Research PowerPoint PPT Presentation
Biomedical Informatics and Interdisciplinary Research - Title: Biomedical Informatics and Interdisciplinary Research Author: School of Technology Last modified by: Kane Created Date: 2/24/2005 8:30:42 PM
Title: Biomedical Informatics and Interdisciplinary Research Author: School of Technology Last modified by: Kane Created Date: 2/24/2005 8:30:42 PM
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Chrysanthemum parthenium (L.) Berhn (feverfew) ???, ??? PowerPoint PPT Presentation
Chrysanthemum parthenium (L.) Berhn (feverfew) ???, ??? - Chrysanthemum parthenium (L.) Berhn (feverfew) , Aristolochia fangchi ( ) as anti-inflammatory, contains aristolochic acid (AA ...
Chrysanthemum parthenium (L.) Berhn (feverfew) , Aristolochia fangchi ( ) as anti-inflammatory, contains aristolochic acid (AA ...
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National Experts in Cardiovascular Medicine PowerPoint PPT Presentation
National Experts in Cardiovascular Medicine - * Figure 2. Percentage of Patients with Dose Estimates within 20% of the Actual Dose, as Derived with the Use of a Pharmacogenetic Algorithm, a Clinical Algorithm ...
* Figure 2. Percentage of Patients with Dose Estimates within 20% of the Actual Dose, as Derived with the Use of a Pharmacogenetic Algorithm, a Clinical Algorithm ...
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A1258690270btpMc PowerPoint PPT Presentation
A1258690270btpMc - Major bleeding episodes in 1-2% of all patients ... Full Model: Genetic Clinical (multivariate): ln(dose) = Age Sex Amiodarone Losartan ...
Major bleeding episodes in 1-2% of all patients ... Full Model: Genetic Clinical (multivariate): ln(dose) = Age Sex Amiodarone Losartan ...
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Antimicrobial Agents (Aminoglycosides, tetracyclines, macrolides and other assorted drugs) PowerPoint PPT Presentation
Antimicrobial Agents (Aminoglycosides, tetracyclines, macrolides and other assorted drugs) - Antimicrobial Agents (Aminoglycosides, tetracyclines, macrolides and other assorted drugs) Dr. Jeff Hobden MIP The Aminoglycosides Two or more amino sugars attached ...
Antimicrobial Agents (Aminoglycosides, tetracyclines, macrolides and other assorted drugs) Dr. Jeff Hobden MIP The Aminoglycosides Two or more amino sugars attached ...
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Lawrence J. Lesko, Ph.D., FCP Director of the Office of Clinical Pharmacology and Biopharmaceutics C PowerPoint PPT Presentation
Lawrence J. Lesko, Ph.D., FCP Director of the Office of Clinical Pharmacology and Biopharmaceutics C - Small separation between dose-response curves for preventing emboli and excess coagulation ... Elderly woman in nursing home -Sent to ER with lower GI bleed -Dx ...
Small separation between dose-response curves for preventing emboli and excess coagulation ... Elderly woman in nursing home -Sent to ER with lower GI bleed -Dx ...
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Pesticides PowerPoint PPT Presentation
Pesticides - ... Nobel Prize Control ... Regulation National pesticide control first attempted by: Insecticide Act of 1910 Targeted more ... growth regulator ...
... Nobel Prize Control ... Regulation National pesticide control first attempted by: Insecticide Act of 1910 Targeted more ... growth regulator ...
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Chapter 16 NSAIDs and COX-2-Selective Inhibitors PowerPoint PPT Presentation
Chapter 16 NSAIDs and COX-2-Selective Inhibitors - Chapter 16 NSAIDs and COX-2-Selective Inhibitors Jeffrey A. Katz, M.D. R2 Lee Seung Il Mechanism of Action Prostaglandin Physiology Hyperalgesia (1) sensitize ...
Chapter 16 NSAIDs and COX-2-Selective Inhibitors Jeffrey A. Katz, M.D. R2 Lee Seung Il Mechanism of Action Prostaglandin Physiology Hyperalgesia (1) sensitize ...
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Historical Development of Toxicology PowerPoint PPT Presentation
Historical Development of Toxicology - Historical Development of Toxicology It is one of the oldest practical sciences which began with early cave dwellers who recognized poisonous plants and animals and ...
Historical Development of Toxicology It is one of the oldest practical sciences which began with early cave dwellers who recognized poisonous plants and animals and ...
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Toxicology PowerPoint PPT Presentation
Toxicology - drug clearance mechanisms (renal and hepatic) are limited in newborns ... reduced hepatic blood flow. reduced activities of cytochrome P450 enzymes. gender ...
drug clearance mechanisms (renal and hepatic) are limited in newborns ... reduced hepatic blood flow. reduced activities of cytochrome P450 enzymes. gender ...
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Update of Novel Anticoagulants PowerPoint PPT Presentation
Update of Novel Anticoagulants - Heparin first used in vascular surgery 1930's. LMWH approved ... agent for LMWH for prophylaxis or initial treatment of venous thromboembolism. Treatment of HIT ...
Heparin first used in vascular surgery 1930's. LMWH approved ... agent for LMWH for prophylaxis or initial treatment of venous thromboembolism. Treatment of HIT ...
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Pr PowerPoint PPT Presentation
Pr - Assessment of Efficacy and Safety for Exanta (Ximelagatran) Ruyi He, M.D. Medical Team Leader The Division of Gastrointestinal and Coagulation Drug Products
Assessment of Efficacy and Safety for Exanta (Ximelagatran) Ruyi He, M.D. Medical Team Leader The Division of Gastrointestinal and Coagulation Drug Products
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Management of Side Effects PowerPoint PPT Presentation
Management of Side Effects - Title: Slide 1 Author: MDavey Last modified by: Srubinoff Created Date: 9/5/2006 7:48:11 PM Document presentation format: On-screen Show Company: FCCC
Title: Slide 1 Author: MDavey Last modified by: Srubinoff Created Date: 9/5/2006 7:48:11 PM Document presentation format: On-screen Show Company: FCCC
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Pharmacokinetic drug interactions PowerPoint PPT Presentation
Pharmacokinetic drug interactions - Milk thistle St John's wort (Silibinin) Garlic. Peppermint oil (Menthol) ... St John's wort may significantly reduce the effectiveness of the following by ...
Milk thistle St John's wort (Silibinin) Garlic. Peppermint oil (Menthol) ... St John's wort may significantly reduce the effectiveness of the following by ...
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