NIDA Research and Training Opportunities Jack B. Stein, MSW, Ph.D. National Institute on Drug Abuse National Institutes of Health US Department of Health and Human Services

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NIDA Research and Training Opportunities Jack
B. Stein, MSW, Ph.D.National Institute on Drug
AbuseNational Institutes of HealthUS Department
of Health and Human Services

• Delivery Systems for Substance Abuse Treatment
• September 5-7, 2005

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NIDA
Bringing the full power of Science to bear on

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Hey, were over here!
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Yoohoo Here we are!
NIH
NCI
NIBIB
NCMHD
NIDDK
NCRR
NIDA
NIAID
NIAAA
NICHD
NIEHS
NIGMS
NCCAM
NINDS
NIDCD
NHGRI
NIA
NEI
NIMH
FIC
NHLBI
NIAMS
NIDCR
NINR
NLM
CIT
CSR
CC
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The NIDA Mission

• To lead the Nation in bringing the power of
  science to bear on drug abuse and addiction,
  through
• support and conduct of research across a broad
  range of disciplines
• ensuring rapid and effective dissemination and
  use of research results to improve prevention,
  treatment, and policy

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NIDA Research Is Multidisciplinary
Epidemiology
Treatment
Neuroscience
Behavioral Science
Risk and Resilience
Prevention
AIDS and Other Medical Consequences
Children and Adolescents
Health Disparities
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NIDA FY 2005 Initiatives

• Prevention
• Gene/environment interactions
• Drug exposure and the developing prenatal brain
• Youth/adolescent interventions
• Treatment Interventions
• Behavioral and pharmacological approaches
• Linking drug abuse services with other health
  care systems
• Translating Research into Practice
• Using science to improve providers knowledge and
  skills

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www.drugabuse.gov
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Effective treatment should attend to multiple
needs of the individual.
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Medications are an important part of treatment
for individuals with substance use disorders.

• Methadone-opiate abuse
• Buprenorphine-opiate abuse
• Naltrexone-opiate and alcohol abuse
• Disulfiram (Antabuse)-alcohol abuse
• Acamprosate-alcohol abuse

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Behavioral counseling is a critical component of
effective treatment.

• Behavioral therapy remains the sole available
  treatment for most classes of drug addiction.
• No pharmacotherapies exist for marijuana,
  sedatives, amphetamines, hallucinogens,
  inhalants.
• Combination behavioral/medication therapies is
  key.

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Behavioral Treatments with Strong Scientific
Support

• Cannabis Youth Treatment Series
• Behavioral Treatments for Smoking Cessation
• Cognitive-Behavioral Treatment
• Combined Pharmacotherapies and Behavioral
  Therapies
• Complementary and Alternative Treatments

• Contingency Management Treatments
• Dialectical Behavioral Therapy
• Drug Counseling
• Family Treatments
• Group Behavior Therapy
• HIV Risk Reduction
• Motivational Interviewing/Enhancement
• Multisystemic Therapy

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Treatment does not need to be voluntary to be
effective.
Public Health Approach -disease -treatment
Public Safety Approach -illegal behavior -punish
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Integrated Public Health-Public Safety Strategy
Blends functions of criminal justice and
treatment systems to optimize outcomes
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Clinical Practice and the Community
Treatment Strategies
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Developing an Evidence-Based-Practice is only one
piece of the translation puzzle
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Science to Services Initiative
Collaboration
Capacity-Building
Commitment
Untapped Research Opportunities
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National Drug Abuse Treatment Clinical Trials
Network (CTN)
Criminal Justice Drug Abuse Treatment Studies
(CJ-DATS)
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Drug Abuse Treatment Core Components and
Comprehensive Services
Treatment Plan
Self-Help (AA, NA) Meetings
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• Technology Transfer and the Treatment of
  Addiction
• Journal of Substance Abuse Treatment (Volume 22,
  Number 4, 2002)

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Program Change Model
Institutional Personal Readiness
Resources
Motivation
Stages of Transfer
Program Change
Staff

• 1-Exposure
• (Training)
• Lecture
• Self Study
• Workshop
• Consultant

2-Adoption (Leadership decision)
3-Implementation (Exploratory use)
Program Improve- ment
4-Practice (Routine use)
Organizational Dynamics
Climatefor Change
Staff Attributes
Source Simpson (2002)
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NIDAs International Goals

• Promote International Research Activities
• Support Research Training and Exchange
  Opportunities Globally
• Communicate and Disseminate Science-Based
  Information on Drug Abuse
• Support International Research Collaboration

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Binational Agreements
NIDA and Pavlov Medical University, Russia
Exchange of Letters
NIDA and the Dutch Addiction Program Exchange of
Letters

• NIDA and the Spanish National Plan on Drugs
• Exchange of Letters

DHHS and the Mexican Ministry of Health Letter of
Intent
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NIDA FY 2005 International Activities by Country
Research Support
Fellowships and Meetings
Research Fellowships and Meetings
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NIDA Supports International Research

• Administrative Supplements
• Domestic Grants With Foreign Components
• Foreign Grants
• Partnerships With Other NIH Institutes

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Administrative Supplements

• Proposed by U.S. Grantees
• Related to Existing Grant
• Maximum of
• 100,000 or
• 25 of direct costs
• Requires NIDA Approval

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U.S. Grants With Non-U.S. Components

• Typically Awarded to U.S. Researchers
• Propose Research at U.S. and International Sites
• International Component Part of Original
  Application and Review Process

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International Research Collaboration on Drug
Abuse Program Announcement PAS-03-023

• Support New and/or Competitive Continuation R01
  Grants for Projects Conducted in Whole or in Part
  Outside the U.S.
• Research Must Be Conducted by U.S. Investigators
  in Collaboration With non-U.S.-Based
  Investigators
• Recent Awards
• DA17317Addiction Treatment in Russia Oral and
  Depot Naltrexone
• DA17620Interventions With HIV and HIV- IDUs in
  Ukraine

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Non-U.S. Grants

• Awarded to non-U.S. Researchers
• Research Conducted Outside the U.S.
• Scored Competitively by NIH
• Must Represent a Special Opportunity

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NIDA Partnerships With the Fogarty International
Center

• Available in Most Countries
• FIRCA (Fogarty International Research
  Collaboration Award)-U.S. grantee
• ICOHRTA (-International Clinical, Operational,
  Health Services Research Training Award)-non-U.S.
  grantee

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Training and Exchange Opportunities
Research Exchanges
Fellowships
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INVEST Research Fellowships

• Rigorous Postdoctoral Research Training
• In the U.S.
• With a NIDA-funded scientist
• Professional Development Activities
• Meet with NIDA officials
• Identify NIDA grantees interested in future
  collaboration
• Stipend Plus
• Travel
• Health insurance
• Professional development activity allowance

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NIDA Humphrey Drug Abuse Research Fellowships

• 10-Month Academic Program
• For midcareer professionals
• Preeminent U.S. university
• 6-Week Professional Affiliation With NIDA-Funded
  Researcher
• Professional Development Activities
• Meet with NIDA officials
• Identify NIDA grantees interested in future
  collaboration
• Tuition and Monthly Stipend Plus
• Travel support
• Health insurance
• Professional development activities allowance

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Distinguished International Scientist
Collaboration Awards and U.S. Distinguished
International Scientist Collaboration Awards

• Support for 1- to 3-Month Research Exchanges
• 6,500 per month for traveling researcher
• Travel support
• Choose the Travel Option That Works Best for the
  Research
• DISCA non-U.S. based researcher travels to U.S.
• USDISCA NIDA grantee travels to partners
  country
• Highly Qualified Senior Researchers

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Dissemination and Exchange of Information
International Meetings
NIDA International Forum
Satellite to CPDD
International Program web site
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www.international.drugabuse.gov

• Announcements
• Fellowships and Other Research Opportunities
• INVEST, DISCA and USDISCA application forms
• Travel Awards
• Meetings
• Upcoming events
• Summaries of past meetings
• Additional Resources
• Frequently Asked Questions

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NIDA International Forum Satellite to CPDD
Growth of Forum Participation

• June 1720, 2005, Orlando, Florida
• Plenary Sessions
• Workshops
• Poster Presentations
• Networking
• Travel Awards (Deadline February 1)

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NIDA International Program Alumni Contribute to
the Scientific Community

• NIDA and NIH Awards
• Scientific Publications
• Working With International Organizations

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NIDA International Program Alumni Contribute to
the Scientific Community

• Examples of Scientific Publications in 2004

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Where Do We Go From Here? Some Research
Questions to Consider

• We need a science of larger social units
• What are the components and characteristics of
  (integrated) treatment systems able to deliver
  effective interventions that can
• -serve large numbers of people
• -be broadly adopted by different settings
• -be consistently implemented with fidelity
• -produce replicable and long-lasting effects
• -at a reasonable cost

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• Steven W. Gust, Ph.D., DirectorDale S. Weiss,
  Program Analyst
• www.international.drugabuse.gov