OOGENESIS

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OOGENESIS

• DR.SHABANA ALI

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FEMALE REPRODUCTIVE SYSTEM
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INTRAUTERINE LIFE 2nd wk..yolk sac 5th wkgonades 3rd_5thmonth ..mitosis 7thmonth.. degeneration 40,000 at birth 500 ovulation, One oocyte is released in each cycle
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INTRAUTERINE LIFE Primordial follicle meiosis I (prophase)arrest AT PUBERTY Monthly ovarian cycle Primary follicle Secondary follicle Secondary oocyte, One polar body. (ovulation)if fertilization occur mature ovum,polar bodies
Resume
Meiosis one complete
2nd meiosis
Metaphase arrest
Meiosis 2 completes
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Intrauterine life Primordial follicle At puberty Primordial follicle Primary follicle Secondary follicle
Primary oocytes Secondary oocyte
Ist meiotic divison till prophase .Complets Ist meiotic division .Starts 2nd meiotic division till metaphase
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• Every month,15-20 follicles are selected and they
  mature in three stages
• 1.primary/preantral
• 2.secondary/antral-longest
• 3.preovulatory-37 hrs before ovulation

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INTRAUTERINE LIFE
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PRIMORDIAL FOLLICLE
1.Primary oocyte 2.flat cell layer
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PRIMARY FOLLICLE
1.granulosa cells..stratfied cuboidal
cells 2.zona pellucida..Acelluler,glyco protein
layer,impermeable 3.theca folliculitheca externa
and interna
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SECONDARY FOLLICLE
1.Antrum 2.cumulus oophorus 3.size-increased 4.25m
m in size
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CORPUS LUTEUM
1.cell number increased 2.vascularity
increased 3.size more than 25mm
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CORPUS ATRETICUM
1.cell number decreased 2.vascularity
decreased 3.degeneration
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CORPUS ALBICAN
1.Fatty degeneration of cells 2.Fibrous tissue
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Gonadotropins, Hormones, and the Ovarian and
Uterine Cycles
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Pituitary-Ovarian Axis
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oogenesis
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