Xerophthalmia - PowerPoint PPT Presentation

Loading...

PPT – Xerophthalmia PowerPoint presentation | free to download - id: 56dcff-OTViM



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

Xerophthalmia

Description:

Xerophthalmia, is a Vitamin A deficiency- It is not hereditary- dietary deficiency. However, in a test done with rats, there were some signs that ingesting fat ... – PowerPoint PPT presentation

Number of Views:1473
Avg rating:3.0/5.0
Slides: 14
Provided by: Kasa7
Learn more at: http://bio200-nutrition.wikispaces.com
Category:

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: Xerophthalmia


1
Xerophthalmia
  • Its not a reptile

2
What is Xerophthalmia?
Xerophthalmia, is a Vitamin A deficiency- It is
not hereditary- dietary deficiency. However, in
a test done with rats, there were some signs that
ingesting fat soluble vitamins or the lack of,
can have some genetic correlation.
Xerophthalmia is a medical condition where the
eye fails to produce tears.
3
Pathology
  • It is a severe vitamin A deficiency and is
    described as severe dryness to the conjunctiva
    and cornea.
  • The Cornea becomes dry and wrinkled.
  • If untreated, can lead to corneal ulcerations.
  • And ultimately blindness

4
Relation to Rabbits
  • Rabbits developed Xerophthalmia on a Vitamin A
    deficient diet for 4-6 months.
  • 1st change- lusterless graying of the central
    corneal epithelium after 16-18 weeks
  • 2nd change-7-10 days after multiple small
    erosions on the interpalpebral fissure
  • 3rd change- 1-2 weeks later keratinized plaque
    developed
  • 4th change- cells began to flatten
  • 5th change- decreased number of microvilli
  • Rabbits are a good model for these studies

5
Background
Usually affects children under the age of 9 in
developing countries Accounts for 20,000-
100,000 new cases of childhood blindness in these
countries Largely found in Africa and Southern
Asia Develops over the course of a few months,
as the lacrimal gland stops producing tears.
Also, Bitots Spots may develop, which are
clumps of Keratin debris that build up inside the
conjunctiva and leads to night blindness Corneal
ulcerations and complete blindness Can also
affect those who do not receive the adequate
amount of vitamin A.
6
Background Cont..
  • Can be associated with Sjogren' s syndrome- dry
    mouth and dry eyes.
  • Systemic lupus erythematosus-when tissues attack
    its own immune system
  • Rheumatoid Arthritis- Severe pain in the joints
  • Scleroderma-disease of the connective tissue,
    spotting of the skin, spontaneous scarring and
    bleeding because of overactive immune system.
  • Hypothyroidism-abnormally slow thyroid production
  • All are associated with one another

7
Preference and RDI
  • There is no sex preference, only age.
  • Younger children in developing countries
  • Minimum daily intake for vitamin A-
  • Children 1-3 300mcg
  • 4-8 400mcg
  • Males 19-70 900mcg
  • Females 19-70 700mcg

8
Treatments
  • Two types Symptoms and Deficiency
  • Symptoms artificial tears, i.e., eye drops, and
    increase humidity, and wrap around glasses when
    outdoors
  • Deficiency Vitamin A multivitamin or supplement
  • Eating foods high in Vitamin A
  • However, treatment for deficiency can only go so
    long until one may need surgical help.
  • Submandibular gland transfer for severe
    Xerophthalmia.
  • In a test of seven, six of the seven were
    successful in achieving revascularization.

9
Breakfast
10
Lunch
11
Dinner
12
Questions?
  1. What is Xerophthalmia?
  2. Vitamin A deficiency where the eye fails to
    produce tears
  3. Are there any other treatments besides High
    intake of Vitamin A?
  4. Yes, Submandibular gland transfer
  5. Who is most likely to be affected?
  6. Children in third world countries

13
Medicine.Net. "Definition of Xerophthalmia." 26
May 2003. http//www.medterms.com/script/main/art.
asp?articlekey6040
Paniello, R. C. "Supplemental Content." National
Center for Biotechnology Information. U.S.
National Library of Medicine, Jan. 2007. Web. 28
Feb. 2012. http//www.ncbi.nlm.nih.gov/pubmed/1720
2928
Vanhorn, D. L., and W. H. Schutten. "Supplemental
Content." National Center for Biotechnology
Information. U.S. National Library of Medicine,
19 Sept. 1980. Web. 27 Feb. 2012.
lthttp//www.ncbi.nlm.nih.gov/pubmed/7409998gt.
About PowerShow.com