Differences in systolic and diastolic BP between patients randomized to atorvastatin or placebo

1
Differences in systolic and diastolic BP between
patients randomized to atorvastatin or placebo
Time point Difference in systolic BP (mm Hg) p Difference in diastolic BP (mm Hg) p
Baseline 0.0 0.95 0.0 0.87
6 weeks 0.9 0.02 0.6 0.005
6 months 1.1 0.002 0.6 0.001
Closeout 0.1 0.82 0.0 0.76
Dahlöf B. American Heart Association Scientific
Sessions 2004. Nov 7-10, 2004 New Orleans, LA.
2
Primary and secondary end points
End point Valsartan 160 mg Valsartan 160 mg/ simvastatin 20 mg Valsartan 160 mg/ simvastatin 80 mg p vs valsartan 160 mg
Mean change from baseline in mean 24-hour ASBP (mm Hg) -9.2 -9.3 -9.6 NS
Mean change from baseline in mean 24-hour ADBP (mm Hg) -5.5 -5.5 -6.0 NS
LDL (mg/dL) 2.7 -34.8 -47.2 lt0.05
CRP (mg/dL) -0.16 -0.2 -0.7 lt0.0023
Rajagopalan S. American Heart Association
Scientific Sessions 2004. Nov 7-10, 2004 New
Orleans, LA.