rDNA and Risk: Controversies of the 1970s and 80s - PowerPoint PPT Presentation

Loading...

PPT – rDNA and Risk: Controversies of the 1970s and 80s PowerPoint presentation | free to view - id: 7e0881-Nzg4N



Loading


The Adobe Flash plugin is needed to view this content

Get the plugin now

View by Category
About This Presentation
Title:

rDNA and Risk: Controversies of the 1970s and 80s

Description:

... (Pauling, 1949) DNA as hereditary material (Hershey and Chase, 1951) Structure of ... public involvement in rDNA debate Cambridge City Council hearing, June ... – PowerPoint PPT presentation

Number of Views:25
Avg rating:3.0/5.0
Slides: 8
Provided by: Office2948
Category:

less

Write a Comment
User Comments (0)
Transcript and Presenter's Notes

Title: rDNA and Risk: Controversies of the 1970s and 80s


1
rDNA and Risk Controversies of the 1970s and 80s
  • HSCI E137 Feb 23, 2011

2
Some of the scientific developments preceding the
biotech era
  • Search for hereditary basis for traits and
    diseases (Penrose, 1940s)
  • One gene-one enzyme hypothesis (Beadle and Tatum,
    1940s)
  • Concept of molecular disease (Pauling, 1949)
  • DNA as hereditary material (Hershey and Chase,
    1951)
  • Structure of DNA (Watson and Crick, 1953)

3
Scientific developments
  • The central dogma DNA makes RNA makes protein
    (Crick, 1958)
  • Frog cloned (Gurdon, 1961)
  • Discovery of restriction enzymes (late 1960s)
  • Recombinant DNA (1973)

4
Krimskys Biotechnics
  • Ks view of technology as contingent, not
    autonomous cell-as-factory metaphor
  • K divides the history of the early biotech
    revolution by decade
  • Defining events in the first decade (1970s)
  • 1973 first successful recombinant DNA
  • 1974 formation of NIH RAC
  • 1975 Asilomar conference

5
Defining events 1970s
  • 1976-77 public involvement in rDNA debate
  • Cambridge City Council hearing, June 26, 1976
    (video)
  • 1977 Cambridge passes rDNA law
  • 1977 Rifkins debut as anti-genetics activist

6
Rifkin protesting in the 1990s
Rifkin in 2009
7
1980s developments
  • Growing commercialization of biotech RDLPs and
    biopatenting policies
  • From lab containment to deliberate release
  • Field testing of ice minus (1982-1987)
  • EPA steps in as regulator
  • Risk assessment geneticists vs. ecologists
About PowerShow.com