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Prevention and Control of Avian Influenza

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Prevention and Control of Avian Influenza ... H5,H7,H9 Low Pathogenic Avian Influenza ... – PowerPoint PPT presentation

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Title: Prevention and Control of Avian Influenza


1
?????????? (515-479) ??????
??????????????????????????????? Prevention and
Control of Avian Influenza
??? ?????????? ?????????? ????????????
4440114 ???????????????? ??.??.?.???? ?????????
2
?????????
  • ????
  • ?????????????????????????????????
  • ??????????????????????????????????????????????????
    ??????????????????????
  • ????????????????????????????????????????????
  • ??????????????????????????????????????????
  • ????

3
(No Transcript)
4
(No Transcript)
5
(No Transcript)
6
?????????????????????????????????
  • Influenza Virus
  • Single RNA ????????????
  • ????????????? 3 ???? ??? A, B ??? C
  • ??????????????????????????????????????????????????
    ??????? ??? ???? A
  • ?? glycoprotein ????????????????????????????????
    2 ???? ???
  • Hemagglutinin ???????????????? 15 ????
  • Neuraminidase ???????????????? 9 ????

7
????? ??????, 2546
8
????????????????????????????????? (???)
  • ?????????????????????????????????????? ??????? H
    ??? N ????????????????????????????????????????
    HxNx
  • ??????????????????????????????????????????????
    ??????????????????????????????????????????????????
    ???????????????????????????????????????????????

9
????????????????????????????????? (???)
  • ??????????????????????????????????????????????????
    ?????????????????????????????????????????????????
    ??????????????????
  • ??????????????????????? ??????????????????????????
    ??????????

10
????????????????????????????????? (???)
  • ??????????????????????????????????????????????
    ???????? 2 ???????????
  • Highly Pathogenic Avian Influenza (HPAI)
    ???????????????????????????
  • ???????????????????? H5,H7,H9
  • Low Pathogenic Avian Influenza (LPAI)
    ??????????????????????????????

11
???????????????????????????
???????????????????????????????????????????????
???????????? ??????? ????????? HPAIV
?????????????????????????? ???????????????????????
?? (???????? 1)
12
????????????????
  • ?????????????????????????????????????????
    ?????????????? ????????? (??????, 2546)
  • ?????????????????????? 2-3 ??????? ??? 3 ???
  • ???????????????????????????????????????
  • 14 ???

13
????????????????
  • ???????????????????????? ???????? ???????????????
    ?????????????? ????????????????????????? ????
    ?????? ????? ?????? ????? ????????????????????????
    ???????????? (Easterday ??????, 1997 ???????
    ??????, 2546)

14
???????????????? (???)
  • ????????????????? antigenicity ????????
    influenza ?? 2 ???
  • Antigenic drift ???????????????????????????
    ???????? variants ???? ?????????????????????
    ???? Antigenic drift ????????????????????????
  • Antigenic shift ??????????????????????????????????
    ????????????? ???????? subtype ???? ??? H ????
    N ???????? ??????????????? H ???????? N
  • ???????????????????????? influenza ?????????????
    ?????????????????????? ?????????????
    ??????????????????? segments ?????????????????
    (Genetic Reassortment)

15
???????????????? (???)
???????????????????????
16
???????????????? (???)
????? ???????? ?????????
17
???????????????? (???)
  • ?????????????????????

18
???????????????? (???)
  • ????????????????????

19
???????????????? (???)
  • ????????

20
???????????????? (???)
  • ???

21
???????????????? (???)
  • Fomite
  • ????????????? ???????????????????????????????????
    ??????? ??????????????????????????????????
  • ??????????????????????? ??????????? fomites
    ????????????????????? ????????? ????? AI virus
    ??????????????????????????????????????????????????
    ???????????????????????

22
(No Transcript)
23
??????????????????????
  • ????????????????
  • ??
  • ???????????????
  • ????????????
  • ????????

??????????????
?????
Biosecurity
24
?????????????????????? (??????????)
????? ??????????
???
?????
???????
????????
??
???????????? ????????????????????? ??????
25
?????????????????????????????????
26
????????2 ??????????????????????????AI
????????? ?????????? ???????? H5/H7 ??????????? ???????????? ??????? ????????????? ??????? ?????????? ??????????? ?????????? ????????? ??????
HPAI/ LPAI ??????????????????????????? ????? ???/ ??? stamping- out
HPAI/ LPAI ??????????????????????????? ?? ??? stamping- out
HPAI/ LPAI ??????????????????????????? ?? ??? Vaccination
HPAI/ LPAI ??????????????? ????? ???/??? stamping- out
HPAI/ LPAI ??????????????? ?? ??? stamping- out
HPAI/ LPAI ??????????????? ?? ??? Vaccination
????? Capua. ??? Marangon (2003) ????? Capua. ??? Marangon (2003)
27
????????????????????????????????? (???)
??????????????
???????????????????
????????????????????????
????????????
?????????????????????????????????????????
28
???????????????????????????????????????
?????????????????????????????????? (Innate
passive immunity)
????????????????????????????? (active immunity)
??? V.
H subtype ????????
??????
?????????
29
????????????????????????????????????????????
1. Inactivated homologous vaccine
2. Inactivated heterologous vaccine
3. Recombinant vaccine
30
????????????????????????????????????????????
1. ?????? Inactivated homologous vaccine
2. ?????? Inactivated heterologous vaccine
3. Recombinant vaccine
31
????
  • ???????????????????????????????????????
    ?????????????????????????
  • ??????????????????????????????????????????????????
    ?????? ???????????????????????????????????????????
    ???????????????????????? ?????????????????????????
    ??????????????????????????????????????????
    ???????? ???????????????????????????????????????
  • ??????????????????????????????????????????????????
    ?????????????????????????????? ???????????????????
    ????????????????????

32
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