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???PBL????

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Children s Cancer and Leukaemia Group CCLG 2006 ... – PowerPoint PPT presentation

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Title: ???PBL????


1
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2
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PubMed?Books ????
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PubMed?Journal?Nature????? ????
???CNKI????? ????
MedWeb Intute KI Medscape ?? ??????? ???? ???????(?????) ????(?????) ????(?????) ???? (?????)
4
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6
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7
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    ,?????????????????????????,????????,????????

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8
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  • CBM
  • CNKI
  • PubMed

9
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  • ?????????????????,????????????????????????
    ??????,???????????????????,??????????-???,????????
    ????????????????.???????????,????????????3/10??,??
    ???4???????,???????,???2?7???????????????????,???
    ??????????????????

10
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  • 1???,??. TEL-AML1?????????????
    ???.??-??????.2007.22(3227229.
  • 2? ??. ?????????????????????.???????2007.34(2)117
    -120.
  • 3? ???,???,???,???. ?????DNAPKcs?????????????.
    ????????.007(3).13(1)29-30
  • 4? ???????????????????,??????????. ???????1/2004
    19
  • 5? ??????10?????????. 2006.6??????
  • 6??????????????. ??????.2007.6

11
  • 7? Lei Yang, John C. Panetta, Xiangjun Cai,
    Wenjian Yang, Deqing Pei, Cheng Cheng, Nancy
    Kornegay,Ching-Hon Pui, and Mary V. Relling.
    Asparaginase May Influence Dexamethasone
  • Pharmacokinetics in Acute Lymphoblastic
    Leukemia. JOURNAL OF CLINICAL ONCOLOGY. VOLUME 26
    _ NUMBER 12 _ APRIL 20 2008
  • 8?Prospective Analysis of TEL Gene Rearrangements
    in Childhood Acute Lymphoblastic Leukemia A
    Childrens Oncology Group Study. JOURNAL OF
    CLINICAL ONCOLOGY. VOLUME 26 _ NUMBER 13 _ MAY 1
    2008.
  • 9?Methotrexate-Induced Alterations in
  • Beta-Oxidation Correlate With Cognitive
  • Abilities in Children With Acute
  • Lymphoblastic Leukemia

12
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  • ?????????,???????????????????????????

  • ??

13
????
  • 1? Cancer Medicine
  • 2?Health Services/Technology
  • Assessment Text (HSTAT)
  • 3?Eurekah Bioscience Collection
  • 4? Retroviruses

14
  • 5?Clinical Methods
  • 6?GeneReviews
  • 7?Patient Drug Information from Medmaster
  • 8?Medical Microbiology
  • 9?Global Burden of Disease and Risk Factors

  • ??

15
????
  • 1????
  • ?? ???? ???R733.7/49  ????2000?09??1?  ??1
    26
  • 2??????????
  • ?? ????? ???R733.7  ????2002?07??1?  ??182
  • 3????????? ???????
  • ?? ?? ???? ???R733.7/62  ????2000?04??1?  ??
    318
  • 4?????????
  • ?? ?????? ???R733.7/YEG  ????2000?02??1?  ??
    261
  • 5???????????
  • ???????   SS?10423151   ???R725.5  
    ????2001?06??1?  ??886

  • ??

16
????
  • 1?Leukemia
  • 2?Leukemia and Lymphoma
  • 3?Leukemia Research
  • 4?British Journal of Cancer
  • 5?Bone Marrow Transplantation
  • 6?Nature Reviews Cancer
  • 7?Nature Clinical Practice Oncology

  • ??


17
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  • 1????????
  • 2????.???
  • 3???????
  • 4???????
  • 5???????
  • 6???
  • ??

18
???????
  • ???????
  • ????????????????(???(IAQ)????????????)????
    ???????????????????????    
  •    ????????????????????????????,????????????
    ??????     ???????,????,?????????????,?????????
    ??,??? ?????????????,???????????????,
    ?????????????,??????????, ??????????????? ?

19
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    ?????,?????????????????
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20
  • ?????????????????????
  • ???? 1? ???????????????????????? 2?
    ???????????????????????????? 3?
    ????????????????????????? 4? ?????????????????

  • ??

21
????
  • The LeukemiaLymphoma Society

The Leukemia Lymphoma
Society???????,????????????????????????,??????????
?????????????????????????????????
22
  • American Cancer Society
  • ???????????
  • ??????????????
  • ??????????????
  • ???? - ?????????
  • ??????????????
  • ?????????????

23
  • Association of Cancer Online Resources
  • ???????????
  • ???????????,?
  • ?????????????
  • ????????????
  • ????????????
  • ??(?????????)??
  • ?????????????

24
  • The National Childrens Cancer Society
  • ?????????
  • ???????????
  • ???????????
  • ?????????,?
  • ?????

  • ??

25
???????
  • ??
  • Medscape
  • Medscape????
  • ????????CME
  • ???????????
  • ????????????
  • ???????????????????????? ??????????
    ????????????????????????????????????????????,???
    ???????????????????

26
  • ?????????
  • NIC?????????
  • ????????,????
  • ?????????????
  • ???????1937????
  • ??????NIC?????
  • ?????????????1971???????????NIC?????,??????????
    ??NIC??????????(?????????PDQ??????????????????????
    ?????????????)?????????????????????

27
  • International Agency for Research on Cancer
  • IARC?WHO????
  • ?,??????????
  • ????????????
  • ????????????
  • ??????????????????????,???????????????IARC???
    ?????????,??????????????????????????????????????
    ?????????????????????????????????????

28
  • The Institute of Cancer Research
  • ???????????????????????????????????????
    ???????????????????????????????
  • Centers for Disease Control and Control and
    Prevention
  • The National Institute of Environmental
    Health Sciences
  • ?????????????

29
  • Puget Sound Blood Center
  • ???????????
  • ???,??????????
  • OncoLink
  • OncoLink??????
  • ????Abramson?????
  • 1994???,???????
  • ?????????????,????????????????????????????????
    ????

30
  • The University of Texas MD Anderson Cancer
    Center
  • ??????????
  • ????????????
  • ??????????
  • Cancer Research UK
  • ???????????
  • ????????????
  • ???????????

31
  • Childrens Cancer and Leukaemia Group
  • CCLG???????
  • ??????2006???,
  • ????????????
  • ????????????
  • ????????????
  • ?????????????
  • ???????????????????????????????

  • ??

32
  • ??
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  • ?1957?,??????
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    ????????????????????????

33
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34
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35
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36
????
  • ??
  • Leukaemia Research
  • ?UK???????????????????(???????????
    ????????)??????
  • Cancer Care
  • CancerCare?????
  • ??????,??????
  • ?????(???????
  • ?????)?????,???????CancerCare???????????????,
    ???????????????????????

37
  • Cancerbackup
  • ????,?????
  • ????????????
  • ?????,???????
  • ??????????
  • Leukaemia Research Fund
  • LRF????????,
  • ????????,???
  • ?????????????
  • ?????????????
  • ????????????????????????????????????????????
    ?,???????????????????

38
  • Leukaemia Care
  • Leukaemia Care????????,???????????????
    ???????????????,????????????????????????
  • The Anthony Nolan Trust
  • ????????????
  • ????????????
  • ????????????
  • ??????????????????

39
  • CLCSargent
  • CLCSargent??????
  • ????,?????????
  • ??????????????
  • ???????????????
  • ???????????????????????????????????????????????
    ?????
  • CureSearch
  • CureSearch??????
  • ?????????,????
  • ??????????????
  • ???????????
    ??

40
  • ??
  • ????????
  • ????????
  • ??????????????
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41
????
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  • The Cancer Warriors Webring
  • ?????????
  • ???????????
  • The Blood and Marrow Transplant Information
    Network
  • ?????????
  • ?????????????

42
  • National Marrow Donor Program
  • ??????????,
  • ????????????
  • ????,???????
  • ???????

  • ??

43
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    ????????,??????????????????????

44
  • ????????????
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  • ???????,?????
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  • ?????????????,
  • ?????????????
  • ??,???????????????????????????????????????????,
    ???????????????????,??????????????????????????????
    ??????????????????????????????????????????

  • ??

45
????
  • ??
  • OncoChat
  • ???????????
  • ?????????????
  • ????????????????
  • The Candlelighters Childhood Cancer Foundation
    National office
  • ???1970?,???
  • ?????????????
  • ?????????????
  • ????,???????????????,????????

46
  • Blood Counts Information for Kids with Cancer
  • ????????????
  • International Union Against Cancer
  • UICC??????
  • ?????,?????
  • ?????????

  • ??

47
  • ??
  • 39???
  • 39???,?????
  • ?????,?????2000
  • ?3?9?? 39??????
  • ????,????????
  • ???????????????????????,??????????????????????
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48

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