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Treatment Recommendations of swine flu

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Suctioning, bronchoscopy, or intubation. ... School children at high risk of complications or have been in close contact with confirmed or suspected case. – PowerPoint PPT presentation

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Title: Treatment Recommendations of swine flu


1
Treatment Recommendations of swine flu
  • By

Nesrien Mohammed Shalabi Ass. Prof of Thoracic
Medicine 5/5/2009
2
The CDC recommends
  • Patients should seek immediate medical care.
  • Self isolation in their home.
  • Patients must use face mask.
  • Other household members should be given infection
    control instruction.
  • Supportive treatment including- bed rest,
    increased fluid consumption, cough suppressants,
    antipyretics and analgesics.

3
Hospitalized Patients
  • Place patients in a single patient room with door
    kept closed.
  • An airborne-infection isolation room can be used.
  • Suctioning, bronchoscopy, or intubation.
  • Patient should wear a surgical mask when outside
    their room.
  • Encourage patients to wash their hand frequently.

4
Severely ill patients
  • Signs of severe disease include-
  • Cyanosis, dehydration, altered mental status
  • Apnea, tachypnea, dyspnea.
  • Need Mechanical ventilation

5
Antiviral Drugs Empiric
  • Should be considered for-
  • Confirmed, probable or suspected cases of swine
    influenza.
  • Treatment of hospitalized patients and patients
    at higher risk for influenza complication.
  • Initiation of antiviral agents within 48 hours of
    symptom onset the recommended duration of
    treatment is 5 days.

6
Prophylaxis antiviral agents
  • Should be considered in the following individuals
    (pre-exposure or post-exposure)-
  • Close household contacts of a confirmed or
    suspected case who are at risk.
  • School children at high risk of complications or
    have been in close contact with confirmed or
    suspected case.
  • Travelers to Mexico who are at high risk for
    complications.
  • Health care providers or public health workers.

7
Pre exposure prophylaxis
  • Any health care provider who is at high risk for
    complication.
  • Individuals not considered to be at high risk but
    who are nonetheless traveling to Mexico or
    working in areas with confirmed cases.

8
Antiviral Drugs
  • There are four influenza antiviral drugs-
  • Oseltamivir (brand name Tamiflu)
  • Zanamivir (brand name Relenza)
  • Amantadine (brand name Lysovir)
  • Rimantadine (brand name Symmetrel)
  • The swine influenza A(H1N1) viruses in humans
  • Resistant to amantadine and rimantadine.
  • Sensitive to oseltamivir and zanamivir.

9
Benefits of Antiviral Drugs
  • Antiviral can make illness milder with faster
    improvement.
  • Prevent serious influenza complications

10
Oseltamivir (Tamiflue)
  • It inhibits neuraminidase which is a glycoprotein
    on the surface of influenza virus that destroys
    an infected cells receptor viral hemagglutinin.
  • Forms
  • Oral capsules 30mg, 45mg and 75mg.
  • Powder for suspension that contain 12mg/ml after
    reconstitution.
  • Adult dose
  • Treatment of acute illness 75 mg /12 hours for 5
    days
  • Prophylaxis 75 mg once daily for 10 days.

11
Zanamivir (Relenza)
  • Forms
  • Powder form for inhalation via Diskhaler. The
    circular foil discs contain 5mg blisters. Disks
    contain 4 blisters.
  • Adult dose
  • Treatment of acute illness 10mg twice daily for
    10 days.
  • Prophylaxis of household contact 10mg once daily
    for 10 days.
  • Prophylaxis of community contact 10mg once daily
    for 28 days.

12
Thank You
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