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Proteins Structures

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Proteins Structures Primary Structure Proteins Primary Structure Proteins Sequence of Amino Acids Proteins Primary Structure Proteins Secondary Structure - Alpha ... – PowerPoint PPT presentation

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Title: Proteins Structures


1
Proteins Structures
  • Primary Structure

2
Proteins
  • Primary Structure

3
Proteins
  • Sequence of Amino Acids

4
Proteins
  • Primary Structure

5
Proteins
  • Secondary Structure - Alpha Helix

6
Secondary Structure of Proteins
  • Alpha Helix - hydrogen bonds between amide groups.

7
Secondary Structure of Proteins
  • Alpha Helix - hydrogen bonds between amide groups.

8
Proteins
  • Secondary Structure

9
Secondary Structure Proteins
  • Pleated sheet - hydrogen bonds between chains

10
Shape from Bends, Folds and Loops
  • Tertiary Structure

11
Tertiary Structure of Proteins
  • Hydrogen bonding between side chains
  • Salt Bridges between side chains

12
Tertiary Structure of Proteins
  • Disulfide bonds between the cysteine - SH

13
Tertiary Structure of Proteins
  • Hydrophobic - non-polar interactions

14
Proteins
  • Primary Structure

15
Quaternary Structure of Proteins
16
Quaternary Structure of Proteins
  • Interaction of two or more chains
  • Collagen - triple helix

17
Quaternary Structure of Proteins
  • Interaction of two or more chains
  • Insulin - two chains bonded by disulfide

18
Quaternary Structure of Proteins
  • Interaction of two or more chains
  • Insulin - two chains bonded by disulfide

19
Globular Proteins
  • Heme and Myoglobin

20
Globular Proteins
  • Heme and Myoglobin

21
Globular Proteins
  • Hemoglobin - 4 chains, 4 heme groups

22
Protein Structure
  • Review the four kinds of structure - simple
    definitions.

23
Proteins
  • Primary Structure

24
Hydrolysis breaks primary sequence by splitting
into amino acids
  • Review the four kinds of structure - simple
    definitions.

25
Denaturation
  • Review the four kinds of structure - simple
    definitions.

26
Denaturation
  • Review the four kinds of structure - simple
    definitions.

27
Denaturation
  • Disrupt Hydrogen Bonding - alcohol

28
Denaturation
  • Disrupt salt bridges - acids and bases

29
Denaturation
  • Disrupt disulfide bonds - reducing agents, heavy
    metals.
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