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Title:

The Krebs Cycle

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The Krebs Cycle Occurs in the matrix of the mitochondrion Aerobic phase (requires oxygen) 2-carbon acetyl CoA joins with a 4-carbon compound to form a 6- carbon ... – PowerPoint PPT presentation

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Title: The Krebs Cycle


1
The Krebs Cycle
  • Occurs in the matrix of the mitochondrion
  • Aerobic phase (requires oxygen)
  • 2-carbon acetyl CoA joins with a 4-carbon
    compound to form a 6- carbon compound called
    Citric acid

2
  • Citric acid (6C) is gradually converted back to
    the 4-carbon compound
  • -ready to start the cycle once more
  • The carbons removed are released as CO2
  • -enzymes controlling this process called
    decarboxylases
  • The hydrogens, which are removed, join with NAD
    to form NADH2
  • -enzymes controlling the release of hydrogen are
    called dehydrogenases

3
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4
The Cytochrome System
  • 6 points along pathway where hydrogen is released
    and temporarily bound to NAD
  • Reduced coenzyme NADH2 transfers hydrogen to a
    chain of hydrogen carriers called cytochrome
    system
  • These systems are attached to the cristate of
    every mitochondrion

5
  • Transfer of hydrogen from each NADH2 along system
  • -produces 3 ATP
  • -process called oxidative phosphorylation
  • Complete oxidation of glucose yields 38 ATP
  • -2 during glycolysis
  • -36 during oxidative phosphorylation

6
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7
The role of oxygen
  • Final hydrogen acceptor
  • Combines to form water
  • Controlled by enzyme cytochrome oxidase
  • Presence of oxygen also essential for hydrogen to
    pass along the cytochrome system

8
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