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Physics 053 Handcrafting in the Nanoworld Instructor: Mike Falvo

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Physics 053 Handcrafting in the Nanoworld Instructor: Mike Falvo Carbon nanotube Quantom Dot Tuesday/Thursday 9:30 Myosin: Protein Machine ... – PowerPoint PPT presentation

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Title: Physics 053 Handcrafting in the Nanoworld Instructor: Mike Falvo


1
Physics 053 Handcrafting in the
Nanoworld Instructor Mike Falvo
Carbon nanotube
Quantom Dot
Tuesday/Thursday 930
Myosin Protein Machine
2
PHYS 053 Handcrafting in the Nanoworld So what
is this class about?
3
Nanoscience and Nanotechnology
Examples.
Human Made Nanomachines
Biological Motors
4
Well learn about Nano-objects
Carbon nanotubes, quantum dots, and other
advanced nanomaterials
Proteins, Biological motors, and other
nanobiological systems
Real and imagined human-made nanomachines
5
Unique Properties of the Nanoscale Nanoscience
  • Sticky (intermolecular forces)
  • Shaky (thermal energy)
  • Bumpy (Quantum effects)

6
New Scientific Instruments and Techniques that
have enabled Nanoscience
  • Scanning Probe Microscopy
  • Self-Assembly
  • Nano lithography

7
New Technologies / Applications of Nanoscience
  • Nanoelectronics
  • molecular electronics
  • Quantum computing
  • Biomedical Tech
  • nanosensing
  • tissue engineering
  • Drug delivery
  • Nanomaterials
  • Stronger Lighter
  • Green Tech
  • Smart Materials

8
Why Model Building?
  • We must learn the details of a complex structure
    well in order to build it (pro-active rather than
    passive)
  • Once built, these models are extremely useful
    for brainstorming and coming up with new
    intriguing questions

9
What are we actually going to do?
  • Model Building
  • Readings/Discussions
  • Special Projects

10
Is model building essential? Is it just for kids?
Model Building is an essential part of all
science.
Ask Watson and Crick.
11
Model Building is an essential part of all
science.
Models come in various forms. Physical Models,
Computer Models, Mathematical Models
12
Languages of Science
Math
Spoken/Written
Orthorombic
Covalent Bond
Sub-atomic
Visual
13
Discussion
  • We will discuss Reading Assignments, Building
    Projects, Lectures and what ever else we decide
    to discuss.
  • I expect pro-active participation in these
    discussions. What does this mean?
  • Have comments ready
  • Have questions ready
  • Have opinions to share

You will be given a list of questions to think
about and prepare discussion questions/comments.
In some cases you will be assigned questions
individually for which you will be responsible to
lead a discussion .
14
(No Transcript)
15
What are we actually going to do?
  • Model Building 30
  • Readings/Discussions 30
  • Lectures 15
  • Special Projects 25

16
This Course is an Experiment
This Course is a Group Project
The success of this course depends on your
curiosity and initiative
17
Challenges (for me and you)
How do I teach an advanced subject like
nanotechnology as a first year seminar?
  • A Little bit of basic Chemistry
  • A little bit of basic Biology
  • A little bit of basic Physics
  • A little bit of basic Materials Science
  • . . . ???

Well Stick to the big Picture and the
Overarching Themes
18
Challenges (for you and me)
  • Be Proactive
  • Ask questions, bring questions to class, Share
    your crazy ideas
  • Share your doubts or confusions.
  • Take some of the responsibility for your
    learning in this course

19
Goals
Knowledge Goals
  • Become conversant in the diverse areas of
    Nanoscience
  • Understand the overarching themes of nanoscience
    and the potential and challenges of
    nanotechnology

2nd Order Goals
  • Become on informed citizen on nanoscience issues
    and science in general. How do scientist do what
    they do.
  • Use this class to help inform your long term
    goals (your career, your intellectual future)

Concrete Goals
  • Build cool Models
  • Our Dream Building Amazing models that are of
    actual use to scientists in their research.

20
INTRODUCTIONS
  • Who am I?
  • Graduate of University of Illinois at Urbana
    Champaign (BS Physics,1991)
  • Graduate of UNC-Chapel Hill (PhD Physics, 1997)
  • Research Professor in Physics
  • Who are you?
  • Why are you taking this class?

21
Other Resources
  • Syllabus
  • Course Webpage
  • Blackboard

22
Model Project 0 (MP0) Object in a Bag
Today
  • We will split up into groups of 4 (research
    groups)
  • Each team will try to reconstruct the models in
    each bag using available materials

Between today and Thursday
  • Read MP0 discussion questions on course webpage

Thursday
  • Teams compare models and discuss.
  • Model refinement and completion

23
Research Groups
Group 3 Greg Stahr Christopher Kao Erik
Thiede Elizabeth Moser
Group 2 Dennis Cahill Skipper Iqbal Minh
Huyn Alan Layer
  • Group 1
  • Calvin. Lewis
  • Jake Stringfield
  • Michael. Beben
  • Patrick Moseby

Group 4 Patrick. Ross Zachary. McCaw TJ.
Rider Elizabeth Wall
Group 5 Alvaro. Aldana Steve. Garbin Asif
Khan Stephen Cassells-Hansby
24
Model Project Challenge
  • The National Institutes of Health has challenged
    5 world renowned nanoscience research labs help
    with a disease. It is suspected that there is
    something unusual about the structure of one of
    two proteins (they dont know which). Each team
    is given two samples, one of each type of protein
    from a given individual. Only one team will get
    proteins from a diseased individual.
  • Goals
  • 1. Determine which protein is responsible for the
    disease
  • 2. Determine the normal (healthy) structure of
    each protein
  • 3. Determine the pathological structure of the
    protein that causes the disease.

25
Protein 2
Protein 1
Nanoscience Research Groups
1 2 3 4 5
Healthy Individuals
NIH
1. Determine which protein is responsible for the
disease 2. Determine the normal (healthy)
structure of each protein 3. Determine the
pathological structure of the protein that causes
the disease.
Has Disease
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