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Synthetic%20Biology

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Title: PowerPoint Presentation Author: Davidson College Last modified by: Davidson College Created Date: 7/2/2007 8:28:00 PM Document presentation format – PowerPoint PPT presentation

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Title: Synthetic%20Biology


1
Synthetic Biology
2
6
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(No Transcript)
4
Synthetic Biology
5
What is Synthetic Biology?
6
Discover Magazine Scientists of the Year
7
Undergraduates in Synthetic Bio.
international Genetically Engineered Machines
http//parts.mit.edu/registry/index.php/Main_Page
8
37 Teams in 2006 57 in 2007
http//parts.mit.edu/r/parts/igem/team_list.cgi
9
Registry of Parts - iGEM Resource
http//parts.mit.edu/registry/index.php/Part_Types
10
Lego Assembly for DNA Parts
http//parts.mit.edu/registry/index.php/AssemblyS
tandard_assembly
11
What can you make in SB?
Self-organized Pattern Formation
Arsenic Detector
12
Davidson and MWSU Join Forces
2006 iGEM Teams
http//parts2.mit.edu/wiki/index.php/Davidson_2006
http//parts2.mit.edu/wiki/index.php/Missouri_West
ern_State_University_2006
13
Burnt Pancake Problem 2006
Sorting stacks of burnt pancakes
DNA Pancakes order and orientation
14
Davidson Missouri Western 2006
http//www.bio.davidson.edu/people/kahaynes/FAMU_t
alk/Living_computer.swf
15
Modeling Pancake Flipping
-2 1
-2 -1
A3 1 2 -1 2 -1 -2 1 -2 -2 -1 -2 1 2 1 2 -1
1 2 0 7 0 7 7 0 6 0
-1 2 7 0 7 0 0 7 0 6
-1 -2 0 7 0 7 6 0 7 0
1 -2 7 0 7 0 0 6 0 7
-2 -1 7 0 6 0 0 7 0 7
-2 1 0 7 0 6 7 0 7 0
2 1 6 0 7 0 0 7 0 7
2 -1 0 6 0 7 7 0 7 0
2 1
2 -1
R2 2 Burnt Pancakes 8 vertices, each with degree
3 Each path taken with probability 1/27
16
Pancake Graph Theory
17
Five Prizes in 10 Categories!
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Five Prizes in 10 Categories!
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MO Governor Meets MWSU iGEMmers
20
Hamiltonian Path Problem 2007
21
Davidson Missouri Western 2007
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Split GFP Works!
http//www.bio.davidson.edu/Courses/Immunology/Stu
dents/spring2006/Acker/GFP_halfframe.html
23
Traveling Salesman Problem 2007
24
SB Blends Math and Biology
HHMI Proposals Due Fall, 2007
25
Is SB hard or expensive?
  • Hire rising sophomores
  • Less than 5,000 in lab expenses
  • NSF Undergraduate Biology and Math Program
  • Protocols student-proof and online
  • Creativity and fun encouraged
  • Existing lab equipment and methods
  • Math modeling improves design
  • Fun iGEM competition stimulates students

26
How can SB fit into a curriculum?
  • Seminar course to prepare
  • Research or Independent Study to build
  • Summer research programs
  • Existing Courses Molecular Biology, Genetics,
    Cell Biology, Development, Microbiology,
    Biochemistry, Engineering, Modeling, Lab
    Methods...

27
How can we learn more?
  • Attend iGEM 2007 in Boston
  • Read synthetic biology papers www.bio.davidson.edu
    /Courses/Synthetic/read.html
  • Familiarize yourself with iGEM wiki
  • Form an iGEM team on your campus
  • Put Synthetic Biology in your HHMI proposal

28
Is GCAT participating in iGEM?
  • Encouraging PUIs to join the fun
  • Including iGEM in HHMI request
  • Sharing protocols
  • Making List-serve available
  • Synthetic biology workshops possible
  • Develop curriculum and resources to share

http//parts.mit.edu/igem07/index.php/Davidson_Mis
souri_W
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