FP7 Health - 3rd call

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The Health theme Framework Programme for
Research FP7

Kevin McCarthy Head of Sector Public
Health Directorate Health DG Research European
Commission
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Outline today

• The 7th Framework programme (FP7)
• Rationale and approach
• Basic principles
• Structure
• Pillar 3
• Outcome of first calls
• Present call for proposals
• Some projects

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EU Research Policy -Competitiveness, Quality of
Lifeand Support to EU policies
The key objective of EU Research research policy
(Art. 163 178 of the Treaty) the
strengthening of the scientific and
technological bases of Community industry and
promoting all research activities deemed
necessary for other policies. The core
objectives for Health research in FP7 are
improving the health of the European citizens
and increasing the competitiveness of the
European health related industries and
businesses with emphasis on translational
research.
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FP7 budget (2007-2013) 55 billion
6 of public RD investment in Europe
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Cooperation programmethematic areas (32.4
billion)
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Collaborative research in FP7 The Cooperation
programme

• Thematic Priorities
• Health 6.1
• Food, agriculture, fisheries and
  biotechnology 1.9
• Information and communication technologies 9.1
• Nanosciences, nanotechnologies, materials and
  new production technologies 3.5
• Energy 2.3
• Environment (including climate change) 1.9
• Transport (including aeronautics) 4.2
• Socio-economic sciences and the humanities 0.6
• Security 10. Space 2.8
• Total for collaborative research
  32.4 billion

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Collaborative researchin the Health theme

• Main policy drivers
• Improving health of European citizens
• Increasing competitiveness of European
  health-related industries and businesses
• Addressing global health issues, including
  emerging epidemics

• Budget
• 6.1 billion over 7 years (2007-2013)

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Collaborative research

• across borders and other barriers
• between countries
• multinational consortia, with at least 3 partners
  from 27 EU Member States (MS) Associated
  Countries (AC) eg Albania, Croatia, FYROM,
  Iceland, Israel, Liechtenstein, Montenegro,
  Norway, Serbia, Switzerland, Turkey.
• researchers from any country in the world can
  participate, from industrialised countries and
  from developing countries. eg Argentina,
  Australia, Brazil, Canada, China, India, Japan,
  Korea, New-Zealand, Russia, South-Africa, USA,
  
• between different types of organizationsPublic
  private sector universities, research centres,
  large companies, Small and medium-sized
  enterprises (SMEs), etc.
• between disciplines multidisciplinary,
  translational research

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Scientific excellence at European level

• From policy to funding the best research
  projects
• The policy for Health research is described in
  the FP7 specific programme (available on CORDIS)
• Each year, a work programme is prepared by the
  EC, with the Advisory Group and in consultation
  with the Programme Committee
• Through calls for proposals the EC invites
  researchers from all Europe and beyond to submit
  their proposals
• The very best projects are selected on the basis
  of evaluation by independent experts (peer
  review)
• After negotiation of a grant agreement, a project
  is funded for 2-5 y.

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Submission evaluation
Basic principles

• annual calls single-stage or two-stage
• eligibility check (partners, limits, scope,
  deadline)
• evaluation by panels of independent experts
  overseen by Independent Observers
• 3 criteria Thresholds
• Science Technology excellence 3/5
• Implementation Management 3/5 overall
• Potential Impact 3/5 10/15
• feedback Evaluation Summary Reports (ESRs)

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Evaluation procedure
Proposal submission
Eligibility check
eligible
IER/IAR
1. Individual evaluation
not eligible exclusion
2. Consensus Group meeting
CR ESR
If above threshold
If below threshold
Consensus Report
3. Panel Evaluation
Ethical review (if necessary)
Evaluation Summary Report
Priority list
Commission decision
Report
Reserve list
Rejection
Negotiation
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Funding schemes in the Health theme (3rd call)
Funding schemes upper limits min.
partners Large-scale integrating project
(CP-IP) 12m 3 Network of Excellence (NoE)
12m 3 Small- or medium-scale focussed
research project (CP-FP) 3m or 6m
3 Coordination action (CA) 1.5m
3 Support action (SA) 0.5m 1
for CP-IPs there is also a lower limit to the
requested EC grant 6m. for CAs and SAs there
are some exceptions to the upper limit.
Warning the limits for minimum and maximum
requested EC grant and for the minimum number of
partners are eligibility criteria !
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Collaborative Project (CP) small or medium
scale

• Designed to generate knowledge to improve
  European competitiveness and to meet the needs of
  society or Community policies
• To support research, development demonstration
  activities of a more limited scope than required
  by large scale CPs
• well defined, focused research and technological
  development
• demonstration, where applicable
• project management

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Coordination Action

• Designed to promote support the networking
  coordination of research innovation activities
  at national, regional European level over a
  fixed period
• Establishing in a coherent way coordinated
  actions Programme of work
• - Coordination activities
• - Project management activities
• CA do not conduct ST research!

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Support Action

• Designed to support the implementation of the
  programme
• To complement the other FP6 instruments
• To help to prepare future EU policy activities
• To stimulate, encourage facilitate the
  participation of e.g. SMEs or organisations
  from the ACS
• May combine two types of activities
• - Support activities
• - Consortium management activities
• SA do not conduct ST research!

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The Health themeStructure
pillar 2 Translating research for human health
pillar 3 Optimising the delivery of health
care
pillar 1 Biotechnology, generic tools
technologies for health
cross-cutting issues child health, the health
of ageing population gender-related health
issues
Activity (pillar) 4 Other actions across the
theme
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Collaborative researchin the Health theme

• 1 Biotechnology, generic tools and technologies
• High-throughput research
• Detection, diagnosis and monitoring
• Predicting suitability, safety and efficacy of
  therapies
• Innovative therapeutic approaches and
  interventions

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Collaborative researchin the Health theme

• 2 Translating research for human health
• Integrating biological data and processes
  large-scale data gathering, systems biology
• Research on the brain and related diseases,
  human development and ageing
• Translational research in major infectious
  diseases
• Translational research in other major diseases

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Collaborative researchin the Health Theme

• Pillar 3 Optimising the delivery of health care
  to citizens
• Translating clinical research into clinical
  practice
• Quality, efficiency and solidarity of health care
  systems
• Enhanced health promotion and disease prevention
• including international cooperation in public
  health health systems

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Collaborative researchin the Health Theme

• i) Translating clinical research into clinical
  practice
• Better use of medicines, behavioural and
  organisational interventions, health
  technologies focus on patient safety
• to identify the best clinical practice
• to understand decision making in clinical
  settings in primary and specialised care
• to foster evidence-based medicine and patient
  empowerment

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Collaborative researchin the Health Theme

• ii) Quality, solidarity and sustainability of
  health systems
• Basis for countries to adapt their health
  systems taking into account national contexts and
  population characteristics
• Organizational, financial and regulatory aspects
• Implementation best practice
• Outcomes - effectiveness, efficiency and equity
• Special attention on investment issues and
  human resources

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Collaborative researchin the Health Theme

• iii) Enhanced Health Promotion Disease
  Prevention
• Evidence for best public health measures in
  terms of life style interventions focus on
  the wider determinants of health and how
  they interact at the individual and
  community level
• Diet, stress, tobacco, physical activity,
  nutrition, inequalities
• Mental health to be addressed in life-course
  perspective

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Collaborative researchin the Health Theme

• The Third Pillar
• a completely new activity health policy
  driven
• aims at developing new research methods
• to generate a sound scientific basis
• to underpin informed policy decisions on health
  systems
• to achieve more effective and efficient
  evidence-based strategies of health
  promotion, disease prevention, diagnosis and
  therapy
• in a context set by the overarching values of
  universality, access to good health care,
  equity and solidarity aiming to make
  provision that is patient-centred and responsive
  to individual need
• Users EC, MS, WHO, OECD, clinicians, patients,
  other stakeholders

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• Identifying priority areas for research is
  influenced by a range of factors including

• EU Health Strategy 2nd Programme of Community
  Action in the field of Health (2008-13)
• DG SANCO policy initiatives patient mobility,
  cross-border care, health services, health
  strategy, centres of reference, patient safety,
  mental health, organ transplantation, urban
  health, indicators
• European stakeholders Health Forum,
  EHFG-Gastein, platforms, councils,
• Member States and the High Level Group on Health
  Services and Medical Care and various sub groups

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• influencing factors

• Other operational DGs concerned DG COMP, DG
  EMPL, DG EAC, DG DEV, DG AIDCO, DG REGIO, DG ENV,
  DG TRADE, DG ENTR, EUROSTAT,
• International dimension - WHO (Regional Office
  HQ)
• Wider context of economic reform and growth
  importance of health care as a driver of growth
  and employment locally Not forgetting of course
  -
• FP7 mechanisms (Advisory Group, Programme
  Committee, NCPs )
• Project development, feedback as well as project
  results scientific communities, conferences,
  workshops, consultations

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Scientific excellence at European level

• Topics selection
• FP6 and FP7 actions are taken into consideration
• Workshops and conferences with scientific
  communitiy and others
• Early input from MS AC (strategic priorities)
• Topics are drafted by the Commission services, to
  implement FP7.
• Not all topics / areas can be opened at any one
  timesome areas are closed in some call,
  emphasis placed on others
• Trying to have a structuring effect on European
  research

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Scientific excellence at European level

• Indicative roadmap
• Strategic reflections (- October)
• Hearing with Cabinet (early November)
• Meeting Advisory Group (24 November)
• 1st Draft sent to PC (Programme Committee) (early
  December)
• Meeting with PC to discuss draft (12 January
  2009)
• Updated work programme sent to PC for final
  comments (February)
• Work programme finalised (March)
• Internal consultations (April)
• Interservice consultation (May)
• PC consultation (June)
• Written procedure (July)
• Publication (end-July) or early September
• Deadline December 2009

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Key figures outcome of 1st 2nd calls

• 2007 2008
• (call 2007-A, April 2007) (call
  2007-B, Sept. 2007)
• budget 635 million (2007) 567 million
  (2008)
• proposals received 914 902
• proposals evaluated 893 (ineligible 21) 865
  (37)
• proposals selected 152 (1) 167 (5)
  of proposals evaluated 17 19 (20)
• av. grant per participant 412,000 334,000
• from reserve lists
• 2007-2008 325 projects funded with gt 1.2
  billion

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Health theme in FP71st call 641m, 153 proposals
pillar 2 Translating research for human health
pillar 3 Optimising the delivery of health
care
pillar 1 Biotechnology, generic tools
technologies for health
23 proposals 143m
110 proposals 476m
closed
Activity (pillar) 4 Other actions across the
theme
20 proposals 20m 13.7 of which
plus 2m for ERA-Net on Cancer
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Health theme in FP72nd call 577m 172
proposals
pillar 2 Translating research for human health
pillar 3 Optimising the delivery of health
care
pillar 1 Biotechnology, generic tools
technologies for health
26 proposals 109m
71 proposals 280m
38 proposals 88m
Activity (pillar) 4 Other actions across the
theme
37 proposals 100m, incl. 44m 25m
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Optimizing the delivery of healthcare to
European citizens 2nd call

• Comments across the activity
• Large number of proposals (177) for the 28
  topics of this activity
• Quality of proposals varied considerably
• this new activity was open for the first time
• new funding opportunity in a generally
  underfinanced technical area
• few established Europe-wide research consortia
• Successful proposals
• responded specifically to the topic
• had broad European coverage
• Unsuccessful proposals
• weak description of methodology
• lacked the required multidisciplinarity
• appeared as resubmissions from neighbouring
  programmes (PHP, ICT)

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3.1 Translating the results of clinical research
into practice2nd call

• Topics in second call
• Implementation of research into healthcare
  practice (FP)
• Self-medication and patient safety (FP)
• Patient Safety Research Network (CA)
• Improving clinical decision making (FP)
• Better use of medicines (FP)
• Continuity of clinical care (FP)
• Patient self-management of chronic disease (FP)
• Outcome of evaluation
• 80 proposals evaluated, 21 (26) above threshold
• Two topics not covered.

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3.1 Translating clinical research into practice
3rd call

• Topics proposed topics for 3rd call
• Patient Safety Effective implementation of
  prevention strategies for healthcare associated
  infections Funding scheme CP-FP, max. 3m. (1
  or more projects)
• Improve quality and safety of hospital
  careFunding scheme CP-FP, max. 3m. (1 or more
  projects)
• Complementary and alternative MedicineFunding
  scheme Coordination Action, max. 1.5m. (max.
  1 project)
• Improved treatment of chronic diseases in
  developingcountries Funding scheme CP-FP, max.
  3m. (1 or more projects)

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3.2 Healthcare systems2nd call

• Topics in second call
• Evaluation of disease management programmes
  (FP)
• Health systems and long term care of the elderly
  (FP)
• Mobility of health professionals (FP)
• Health care human resource planning in nursing
  (FP)
• Clinician working time and patient safety (FP)
• Health outcome measures and population ageing
  (FP)
• Trends of population health (FP)
• European system of Diagnosis-related groups
  (FP)
• Outcome of evaluation
• 54 proposals evaluated, 24 (44) above threshold
• Two topics not covered

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3.2 Healthcare systems3rd call

• Topics proposed topics for 3rd call
• Organisation of dementia care Funding scheme
  CP-FP, max. 3m. (1 or more projects)
• Health care outcomes and cost-benefits Funding
  scheme CP-FP, max. 3m. (1 or more projects)
• Primary care quality linkage to costs Funding
  scheme CP-FP, max. 3m. (1 or more projects)
• Impact of cross border collaboration on health
  services Funding scheme CP-FP, max. 6m. (1 or
  more projects)

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3.2 Healthcare systems3rd call

• Topics proposed for 3rd call
• Research access to comparable health care data
  Funding scheme Coordination Action, max.
  1.5m. (max. 1 project)
• Scoping study to address the methodological
  challenges ofquantifying the socio-economic
  burden of brain diseasescompared to other major
  diseases Funding scheme Support Action, max.
  0.5m. (max. 1 project)

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3.3 - Health promotion and disease prevention 2nd
call

• Topics in second call
• Promoting healthy behaviour in children and
  adolescents
• Interventions addressing the gradient of health
  inequalities
• Public health interventions addressing the abuse
  of alcohol
• Evaluation of suicide prevention strategies in
  European countries
• Improve vaccination coverage
• Outcome of evaluation
• 40 proposals evaluated, 17 (42) above threshold
• Two topics not covered

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3.3 - Health promotion anddisease prevention 2nd
call

• Remarks on the outcomes of 2nd call
• substantial interest and broad coverage of topic
  3.3-1 Promoting healthy behaviour in children
  and adolescents
• two topics were not covered
• none of the 2 proposals submitted to 3.3-5
  Improve vaccination coverage were successful.
  Due to the importance of this research topic
  the evaluators suggested to republish this topic
  in a later work programme
• the only proposal submitted to 3.4-7 Mental
  health research conference was not successful

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3.3 Health promotion and disease prevention
3rd call

• Topics proposed for 3rd call
• Child and adolescent mental health Funding
  scheme CP-FP, max. 3m. (1 or more projects)
• Environmental prevention of substance abuse by
  adolescents Funding scheme CP-FP, max. 3m. (1
  or more projects)
• Ageing cohorts Funding scheme CP-IP, max.
  12m. (max. 1 project)
• Birth/Mother-Child Cohorts co-ordination
  Funding scheme Coordination Action, max.
  1.5m. (max. 1 project)
• European child health research platform Funding
  scheme Coordination Action, max. 1.5m. (max. 1
  project)
• Planned IP on a Health Examination Survey
  postponed to WP2010

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Optimising the delivery of healthcareto European
citizens 2nd call

• 3.4 Horizontal CA SA
• Topics in second call successful proposals
• Disease networks of centres of reference Scoping
  study (SA)
• Effectiveness of health investments Scoping
  study (SA)
• Patient mobility and access to information.
  Scoping study (CA/SA)
• Brokering research into policy Scoping study
  (SA)
• A road-map for ageing research (CA/SA)
• Health Services Research conference (SA)
• No succesful proposals
• Mental health research conference (SA)
• Public Health intervention research conference
  (SA)

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Some successful FP7 proposals

• EIS European implementation score for measuring
  implementation of healthcare practice using
  vascular disease as an example, will focus on
  stroke
• COURAGE validated measures of health health
  related outcomes for an ageing population
• TEMPEST investigates how personal
  environmental approaches may complement each
  other in order to develop more effective
  preventive interventions that will encourage
  young people to develop a health lifestyle
• GRADIENT focusing on effective actions to
  reduce the gradient in health inequalities,
  particularly for families children

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Not forgetting on-goingFP6 projects

• EUROVAQ determining the monetary value of
  quality life adjusted year (QALY) across a number
  of European States
• EPIC European prospective investigation into
  cancer, chronic diseses, nutrition lifestyle
• EUROCADET - Impact iof key determinants on the
  current future burden of cancer in Europe
• EURO-PREVOB Tackling the social economic
  determinants of nutrition and physical activity
  for the preventio of obesity in Europe
• HOPE Health promotion through obesity
  prevention across Europe
• MHADIE - Aims to demonstrate the utility and
  feasibility of ICF model in measuring different
  types and prevalence of impairments and
  limitations

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Key factors for success in applying for FP7
funding

• Competition is tough - only the best projects get
  funded
• the proposal must be in scope with the topic
  and the work programme (not wishful thinking)
• the consortium of partners must be excellent
  and appropriate for the task (select the right
  partners)
• the proposal must address all 3 criteria,
• convince the evaluators (dont rely on
  reputation),
• and, of course, respect the basic rules.
  (deadlines, n participants, ceilings, length,
  ethics, )

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The Health Directorate
Director (acting) Dr. Manuel Hallen Medical
and Public Health Research unit (F2) Head of
unit Dr. Manuel Hallen (manuel.hallen_at_ec.europa.e
u) Deputy Head of Unit Dr. Maria Vidal
(maria-jose.vidal-ragout_at_ec.europa.eu) Head of
sector Public Health K. McCarthy
(kevin.mccarthy_at_ec.europa.eu) Infectious
Diseases unit (F3) Head of unit Dr. Alain
Vanvossel (alain.van-vossel_at_ec.europa.eu) Deputy
Head of unit Dr. Anna Lönnroth
(anna.lonnroth_at_ec.europa.eu) Head of IMI sector
Dr. Irene Norstedt (irene.norstedt_at_ec.europa.eu)
Genomics and Systems Biology unit (F4) Head of
unit Patrik Kolar (patrik.kolar_at_ec.europa.eu) Dep
uty Head of unit Dr. B. Mulligan
(bernard.mulligan_at_ec.europa.eu) Health
Biotechnology unit (F5) Head of unit Dr. Arnd
Hoeveler (arnd.hoeveler_at_ec.europa.eu)
Coordination unit (F1) Head of unit Stéphane
Hogan (stephane.hogan_at_ec.europa.eu)
Admin. Finance unit (F6)Head of unit Georgios
Zisimatos(georgios.zisimatos_at_ec.europa.eu)
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Contacts Information
FP7 Health web site http//cordis.europa.eu/fp7/h
ealth NCPs http//cordis.europa.eu/fp7/health/su
pport_en.html Registration as an Expert
https//cordis.europa.eu/emmfp7/ Fact Sheets
http//ftp.cordis.europa.eu.pub/fp7/docs/healthfac
ts_en.pdf FP6 projects database
www.lifecompetence.eu SME participation Dr.
Ludovica Serafini Tel. [phone]
Emailludovica.serafini_at_ec.europa.eu
www.smesgohealth.org International Cooperation
Dr. Indridi BenediktssonTel. 32 2 299 3137
Email indridi.benediktsson_at_ec.europa.eu
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Thank you !

• EU Member States (n 27)
• Candidate/Accession countries
• Croatia
• Turkey
• Countries associated with the FP
• Iceland
• Israel
• Norway
• Switzerland